Anabolic androgenic steroid‐induced hypogonadism, a reversible condition in male individuals? A systematic review

Andrologia ◽  
2021 ◽  
Author(s):  
José de Oliveira Vilar Neto ◽  
Carlos Alberto Silva ◽  
Carlos Antônio Bruno da Silva ◽  
Daniel V. Pinto ◽  
Juan de Sá Roriz Caminha ◽  
...  
Keyword(s):  
Systematic Review ◽  
Anabolic Androgenic Steroid ◽  
Androgenic Steroid ◽  
Reversible Condition

scholarly journals Anabolic-androgenic Steroid use and Psychopathology in Athletes. A Systematic Review

2015 ◽  
Vol 13 (1) ◽  
pp. 101-121 ◽  
Author(s):  
Daria Piacentino ◽  
Georgios Kotzalidis ◽  
Antonio Casale ◽  
Maria Aromatario ◽  
Cristoforo Pomara ◽  
...  
Keyword(s):  
Systematic Review ◽  
Anabolic Androgenic Steroid ◽  
Steroid Use ◽  
Androgenic Steroid

scholarly journals The Prevalence of Anabolic-Androgenic Steroid Misuse in Iranian Athletes: A Systematic Review and Meta-Analysis

2021 ◽  
Author(s):  
Maryam Selk-Ghaffari ◽  
Sakineh Shab-Bidar ◽  
Farzin Halabchi
Keyword(s):  
Systematic Review ◽  
Prevalence Rate ◽  
Meta Analysis ◽  
National Level ◽  
Anabolic Androgenic Steroids ◽  
Significant Heterogeneity ◽  
Anabolic Androgenic Steroid ◽  
Androgenic Steroid ◽  
Global Statistics ◽  
Androgenic Steroids

Background: Due to widespread abuse of anabolic-androgenic steroids among professional athletes and amateur sportsmen and their health-related problems, determining the prevalence and the pattern of anabolicandrogenic steroid misuse at the national level seems to be vital for designing efficient preventive and educational measures. Methods: This systematic review and meta-analysis was conducted via comprehensive searches of the electronic databases including PubMed, MedLine, Scopus, Google Scholar and National Persian Databases including SID, Magiran, IranDoc (between 1980 and Dec 2019 in English and Persian languages) and also from citations in the selected papers. Overall, 39 articles met the criteria and were included in qualitative and quantitative synthesis. Results: The overall prevalence rate of anabolic-androgenic steroid misuse in the Iranian athletic population was 36.2% (95% confidence interval (CI), 29-43) with significant heterogeneity between studies (I2=99.0%, P<0.001). Prevalence rate of anabolic-androgenic steroid misuse among elite, male and younger athletes was higher (P<0.05). Moreover, prevalence rate of anabolic-androgenic steroid misuse among body-building athletes (36.3%) was higher compared to other athletes (30.9%), (P<0.001). Conclusion: Due to the higher prevalence of anabolic-androgenic steroids misuse in Iran compared to global statistics and the potential for serious adverse effects, preventive strategies and policies should be regarded as a real concern for public health.

scholarly journals Anabolic-androgenic steroid administration increases self-reported aggression in healthy males: a systematic review and meta-analysis of experimental studies

2021 ◽  
Author(s):  
Razieh Chegeni ◽  
Ståle Pallesen ◽  
Jim McVeigh ◽  
Dominic Sagoe
Keyword(s):  
Systematic Review ◽  
Meta Analysis ◽  
Experimental Studies ◽  
Fixed Effect Model ◽  
Cochrane Library ◽  
Anabolic Androgenic Steroid ◽  
Androgenic Steroid ◽  
Psychiatric Side Effects ◽  
The Cochrane Library ◽  
Healthy Males

Abstract Rationale Aggression and irritability are notable psychiatric side effects of anabolic-androgenic steroid (AAS) use. However, no previous study has systematically reviewed and quantitatively synthesized effects reported by experimental studies on this topic. Objective We conducted a systematic review and meta-analysis of randomized controlled trials (RCTs) investigating the effect of AAS administration on self-reported and observer-reported aggression. Methods Twelve RCTs comprising a total of 562 healthy males were identified through systematic searches of MEDLINE, PsycInfo, ISI Web of Science, ProQuest, Google Scholar, and the Cochrane Library. Results After excluding one outlier, AAS administration was associated with an increase in self-reported aggression under a random-effects model, albeit small (Hedges’ g = 0.171, 95% CI: 0.029–0.312, k = 11, p = .018), and when restricting the analysis to the effect of acute AAS administration on self-reported aggression under a fixed-effect model (g = 0.291, 95% CI: 0.014–0.524, p = .014). However, the above effects were neither replicated in the analysis of observer-reported aggression nor after restricting the analysis to the effects of the administration of higher (over 500 mg) and long-term (3 days to 14 weeks) doses. Conclusions The present meta-analysis provides evidence of an increase, although small, in self-reported aggression in healthy males following AAS administration in RCTs. Ecologically rational RCTs are warranted to better explore the effect of AAS administration on aggression in humans.

Indications of psychological dependence among anabolic-androgenic steroid abusers.

1990 ◽  
Author(s):  
C. E. Yesalis ◽  
J. R. Vicary ◽  
W. E. Buckley ◽  
A. L. Streit
Keyword(s):  
Anabolic Androgenic Steroid ◽  
Androgenic Steroid

scholarly journals Doping practices in international weightlifting: analysis of sanctioned athletes/support personnel from 2008 to 2019 and retesting of samples from the 2008 and 2012 Olympic Games

2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Alexander Kolliari-Turner ◽  
Brian Oliver ◽  
Giscard Lima ◽  
John P. Mills ◽  
Guan Wang ◽  
...  
Keyword(s):  
Sensitivity And Specificity ◽  
Regional Differences ◽  
Olympic Games ◽  
Anabolic Androgenic Steroid ◽  
Sample Storage ◽  
Support Personnel ◽  
Androgenic Steroid ◽  
In Doping ◽  
Targeted Testing

Abstract Background The pervasiveness of doping and findings of anti-doping corruption threaten weightlifting’s position at the 2024 Olympic Games. Analysing the practices of doping in weightlifters could identify patterns in doping that assist in future detection. Methods We analysed publicly available data on sanctioned athletes/support personnel from the International Weightlifting Federation between 2008 and 2019 and announced retrospective Anti-Doping Rule Violations (ADRVs) from the 2008 and 2012 Olympic Games. Results There were 565 sanctions between 2008 and 2019 of which 82% related to the detection of exogenous Anabolic Androgenic Steroid (AAS) metabolites and markers indicating endogenous AAS usage. The detection of exogenous AAS metabolites, markers of endogenous AAS usage and other substance metabolites varied by IWF Continental Federation (p ≤ 0.05) with Europe (74%, 11%, 15%) and Asia (70%, 15%, 15%) showing a higher detection of exogenous AAS compared to Pan America (37%, 30%, 33%) and Africa (50%, 17%, 33%). When looking at the 10 most detected substances, the nations with the highest number of sanctions (range 17–35) all had at least one overrepresented substance that accounted for 38–60% of all detected substances. The targeted re-analysis of samples from the 2008 and 2012 Olympic Games due to the discovery of long-term metabolites for exogenous AAS resulted in 61 weightlifters producing retrospective ADRVs. This includes 34 original medallists (9 gold, 10 silver and 15 bronze), the highest of any sport identified by Olympic Games sample re-testing. The exogenous AAS dehydrochloromethyltestosterone and stanozolol accounted for 83% of detected substances and were present in 95% of these samples. Conclusion Based on these findings of regional differences in doping practices, weightlifting would benefit from the targeted testing of certain regions and continuing investment in long-term sample storage as the sensitivity and specificity of detection continues to improve.

scholarly journals Intrasexual competition as a potential influence on anabolic-androgenic steroid use initiation

2017 ◽  
Vol 24 (9) ◽  
pp. 1210-1220 ◽  
Author(s):  
Marc Harris ◽  
Michael Dunn ◽  
Tina Alwyn
Keyword(s):  
United Kingdom ◽  
Intrasexual Competition ◽  
Anabolic Androgenic Steroids ◽  
Anabolic Androgenic Steroid ◽  
Potential Influence ◽  
Steroid Use ◽  
Novice Group ◽  
Androgenic Steroid ◽  
The United Kingdom ◽  
Androgenic Steroids

An estimated 293,000 people living in the United Kingdom have used anabolic-androgenic steroids. However, there is currently no intervention to reduce usage available in practice or academic circulation throughout the United Kingdom. This study aimed to test a novel hypothesis that increased levels of intrasexual competition may play an important influential role in the use of anabolic-androgenic steroids. Significantly higher levels of intrasexual competition were evident in users compared to non-users but only in the novice group (0–2 years of experience). The research provides evidence for intrasexual competition potentially influencing anabolic-androgenic steroid use but only during the initial stages of usage.

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