Relationship between the G protein–coupled oestrogen receptor and spermatogenesis, and its correlation with male infertility

Andrologia ◽  
2020 ◽  
Vol 52 (10) ◽  
Author(s):  
Osman Barut ◽  
Muhammed Seyithanoglu ◽  
Faruk Kucukdurmaz ◽  
Bekir Turkay Demir ◽  
Caner Olmez ◽  
...  
2020 ◽  
Vol 277 (4) ◽  
pp. 1121-1127
Author(s):  
Saime Sagiroglu ◽  
Metin Kılınc ◽  
Adem Doganer ◽  
Nagihan Bilal ◽  
Israfil Orhan ◽  
...  

2013 ◽  
Vol 591 (17) ◽  
pp. 4223-4235 ◽  
Author(s):  
G. Cristina Brailoiu ◽  
Khalid Benamar ◽  
Jeffrey B. Arterburn ◽  
Erhe Gao ◽  
Joseph E. Rabinowitz ◽  
...  

2017 ◽  
Vol 137 (10) ◽  
pp. S293
Author(s):  
M. Fábián ◽  
P. Balogh ◽  
F. Rencz ◽  
V. Brodszky ◽  
J. Hársing ◽  
...  

2017 ◽  
Vol 46 (2) ◽  
pp. 723-731 ◽  
Author(s):  
Cai-xia Zhu ◽  
Wei Xiong ◽  
Ma-lie Wang ◽  
Juan Yang ◽  
Hui-juan Shi ◽  
...  

Objective To demonstrate the correlation between nuclear and cytoplasmic G protein-coupled oestrogen receptor (GPR30) expression and clinicopathological features and outcome in patients with ovarian cancer. Methods Nuclear and cytoplasmic GPR30 expressions were determined using immunohistochemistry to identify the intracellular location in tissues from patients with ovarian cancer. Data were correlated with clinicopathological characteristics and outcomes. Results Tissue samples were obtained from 110 patients with epithelial ovarian cancer between 2005 and 2010. Nuclear GPR30 was significantly more frequent in the group of patients with recurrence. The presence of nuclear GPR30 predicted lower overall survival) and 5-year progression-free survival in all patients with ovarian cancer and overall survival in patients with high grade ovarian cancer. Cytoplasmic GPR30 was observed significantly more often in advanced ovarian cancer and did not predict survival. Conclusion This study showed that nuclear GPR30 is an independent negative prognostic indicator in patients with ovarian cancer, especially in those with a high grade malignancy.


2021 ◽  
Vol 25 (3) ◽  
pp. 204-212
Author(s):  
Jan-Hendrik Maiwald ◽  
Susanne Sprung ◽  
Piotr Czapiewski ◽  
Wiebke Lessel ◽  
Anna Scherping ◽  
...  

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