Immobilising effect ofRuta graveolens L. on human spermatozoa: coumarin compounds are involved

Andrologia ◽  
2015 ◽  
Vol 47 (10) ◽  
pp. 1183-1189 ◽  
Author(s):  
Z. Naghibi Harat ◽  
N. Lakpour ◽  
H. R. Sadeghipoor ◽  
M. Kamalinejad ◽  
M. R. Eshraghian ◽  
...  
Author(s):  
P. Hernández-Jáuregui ◽  
A. Sosa ◽  
A. González Angulo

Glycocalyx is the name given by Bennett to the extracellular glycoprotein coat present in some cell surfaces. It appears to play an important role in cell properties such as antigenicity, cell adhesivity, specific permeability, and ATP ase activity. In the sperm this coat can be directly related to such important phenomena as capacitation and fertilization. The presence of glycocalyx in invertebrate spermatozoa has already been demonstrated. Recently Yanagimachi et al. has determined the negative charges on sperm surfaces of mammalian spermatozoa including man, using colloidal iron hydroxide. No mention was made however of the outer surface coat as composed of substances other than those confering a negative charge. The purpose of this work was therefore to determine the presence of a glycocalyx in human spermatozoa using alcian blue and lanthanum staining.


Author(s):  
A. Sosa ◽  
L. Calzada

The dependence of nuclear metabolism on the function of the nuclear membrane is not well understood. Whether or not the function of the nuclear membrane is partial or totally responsible of the repressed template activity of human sperm nucleus has not at present been elucidated. One of the membrane-bound enzymatic activities which is concerned with the mechanisms whereby substances are thought to cross cell membranes is adenosintriphosphatase (ATPase). This prompted its characterization and distribution by high resolution photogrammetry on isolated human sperm nuclei. Isolated human spermatozoa nuclei were obtained as previously described. ATPase activity was demonstrated by the method of Wachstein and Meisel modified by Marchesi and Palade. ATPase activity was identified as dense and irregularly distributed granules confined to the internal leaflet of the nuclear membrane. Within the nucleus the appearance of the reaction product occurs as homogenous and dense precipitates in the interchromatin space.


2001 ◽  
Vol 24 (6) ◽  
pp. 327-334 ◽  
Author(s):  
A. Force ◽  
G. Grizard ◽  
M. N. Giraud ◽  
C. Motta ◽  
B. Sion ◽  
...  

2019 ◽  
Author(s):  
Chem Int

Coumarin and its derivatives are widely spread in nature. Coumarin goes to agroup as benzopyrones, which consists of a benzene ring connected to a pyronemoiety. Coumarins displayed a broad range of pharmacologically useful profile.Coumarins are considered as a promising group of bioactive compounds thatexhibited a wide range of biological activities like anti-microbial, anti-viral,antiparasitic, anti-helmintic, analgesic, anti-inflammatory, anti-diabetic, anticancer,anti-oxidant, anti-proliferative, anti-convulsant, and antihypertensiveactivities etc. The coumarin compounds have immense interest due to theirdiverse pharmacological properties. In particular, these biological activities makecoumarin compounds more attractive and testing as novel therapeuticcompounds.


2020 ◽  
Vol 5 (7) ◽  
Author(s):  
Cara V. Neal ◽  
Atticus L. Hall-McNair ◽  
Jackson Kirkman-Brown ◽  
David J. Smith ◽  
Meurig T. Gallagher
Keyword(s):  

Andrology ◽  
2021 ◽  
Author(s):  
Chuan Huang ◽  
Run‐Xin Gan ◽  
Jian‐Lin Hu ◽  
Feng Liu ◽  
Yan Hong ◽  
...  

Urology ◽  
2002 ◽  
Vol 59 (4) ◽  
pp. 575-578 ◽  
Author(s):  
Murali K Ankem ◽  
Eric Mayer ◽  
W.Steven Ward ◽  
Kenneth B Cummings ◽  
Joseph G Barone

Sign in / Sign up

Export Citation Format

Share Document