scholarly journals SARS‐CoV‐2 infection and venous thromboembolism after surgery: an international prospective cohort study

Anaesthesia ◽  
2021 ◽  
Author(s):  
◽  
Keyword(s):  
Cohort Study ◽  
Venous Thromboembolism ◽  
Prospective Cohort Study ◽  
Prospective Cohort

Inter-observer reliability of a risk assessment model for venous thromboembolism in acutely-ill medical hospitalized patients: Results from a prospective cohort study

2021 ◽  
pp. 026835552110212
Author(s):  
Cassia RL Ferreira ◽  
Marcos de Bastos ◽  
Mirella L Diniz ◽  
Renan A Mancini ◽  
Yan S Raposo ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cohort Study ◽  
Venous Thromboembolism ◽  
Prospective Cohort Study ◽  
Prospective Cohort ◽  
Risk Classification ◽  
Assessment Model ◽  
Kappa Statistics ◽  
Medical Patients ◽  
Observer Reliability

Objectives To analyze the inter-observer reliability of risk for venous thromboembolism (VTE) in a population of adult acutely-ill medical patients. Methods In this prospective cohort study, we collected risk factors and risk classification for VTE using RAM IMPROVE7. Kappa statistics was used to evaluate inter-observer reliability between lead clinicians and trained researchers. We evaluated occurrence of VTE in patients with mismatched classification. Results We included 2,380 patients, median age 70 years (interquartile range [IQR], 58-79), 56.2% female. Adjusted Kappa for VTE risk factors ranged from substantial (0.64, 95% confidence interval [CI], 0.61-0.67) for “immobilization”, to almost perfect (0.98; 95% CI 0.97-0.99) for “thrombophilia”; risk classification was 0.64 (95% CI 0.60-0.67). Divergent risk classification occurred in 434 patients (18.2%) of whom seven (1.6%) developed VTE. Conclusion Despite substantial to almost perfect reliability between observers for risk factors and risk classification, lead clinicians tended to underestimate the risk for VTE.

scholarly journals Duration and magnitude of the postoperative risk of venous thromboembolism in middle aged women: prospective cohort study

BMJ ◽  
2009 ◽  
Vol 339 (dec03 1) ◽  
pp. b4583-b4583 ◽  
Author(s):  
S. Sweetland ◽  
J. Green ◽  
B. Liu ◽  
A. Berrington de Gonzalez ◽  
M. Canonico ◽  
...  
Keyword(s):  
Cohort Study ◽  
Venous Thromboembolism ◽  
Prospective Cohort Study ◽  
Prospective Cohort ◽  
Middle Aged ◽  
Postoperative Risk

scholarly journals Handgrip strength is not associated with risk of venous thromboembolism: a prospective cohort study

2020 ◽  
Vol 54 (4) ◽  
pp. 253-257 ◽  
Author(s):  
Setor K. Kunutsor ◽  
Timo H. Mäkikallio ◽  
Ari Voutilainen ◽  
Jari A. Laukkanen
Keyword(s):  
Cohort Study ◽  
Venous Thromboembolism ◽  
Prospective Cohort Study ◽  
Prospective Cohort ◽  
Handgrip Strength

scholarly journals Sauna bathing reduces the risk of venous thromboembolism: a prospective cohort study

2019 ◽  
Vol 34 (10) ◽  
pp. 983-986 ◽  
Author(s):  
Setor K. Kunutsor ◽  
Timo H. Mäkikallio ◽  
Hassan Khan ◽  
Tanjaniina Laukkanen ◽  
Jussi Kauhanen ◽  
...  
Keyword(s):  
Cohort Study ◽  
Venous Thromboembolism ◽  
Prospective Cohort Study ◽  
Prospective Cohort ◽  
Sauna Bathing

PP80 Risk of venous thromboembolism in women with cancer: a UK-based prospective cohort study

2014 ◽  
Vol 68 (Suppl 1) ◽  
pp. A79.2-A79
Author(s):  
S Sweetland ◽  
A Balkwill ◽  
V Beral ◽  
T Gathani ◽  
J Green ◽  
...  
Keyword(s):  
Cohort Study ◽  
Venous Thromboembolism ◽  
Prospective Cohort Study ◽  
Prospective Cohort

The incidence of venous thromboembolism in thrombophilic children: a prospective cohort study

Blood ◽  
2002 ◽  
Vol 100 (7) ◽  
pp. 2403-2405 ◽  
Author(s):  
Daniela Tormene ◽  
Paolo Simioni ◽  
Paolo Prandoni ◽  
Francesca Franz ◽  
Patrizia Zerbinati ◽  
...  
Keyword(s):  
Cohort Study ◽  
Venous Thromboembolism ◽  
Prospective Cohort Study ◽  
Prospective Cohort ◽  
Factor V Leiden ◽  
Healthy Children ◽  
Factor V Leiden Mutation ◽  
Thrombotic Risk ◽  
Asymptomatic Children ◽  
Risk Period

Antithrombin and protein C and S defects, factor V Leiden mutation, and G20210A prothrombin gene mutation are well-recognized risk factors for venous thromboembolism (VTE) in adults, especially during circumstantial situations such as trauma, immobilization, surgery, or oral contraceptive treatment. The relevance of these defects in predisposing children to VTE is still undefined. In a prospective cohort study we assessed the incidence of spontaneous and risk period–related VTE in asymptomatic children (aged 1-14 years), who were family members of a proband with an objectively diagnosed venous thromboembolic event and a documented single thrombophilic abnormality. We enrolled 143 children from 63 families. Of them, 81 (56.6%) were carriers of an inherited defect, whereas the remaining 62 were free from known genetic or acquired causes of thrombophilia. The mean observation period was 5 years (range, 1-8 years) in each group. Thirty-one risk periods occurred in the carriers group and 20 in noncarriers. Neither spontaneous nor risk period–related VTE occurred in either group during 395 and 296 observation years, respectively. However, circumstances where most of the pediatric thromboses occur (insertion of central venous lines, cancer, and cardiovascular surgery) were not encountered. In conclusion, the thrombotic risk in otherwise healthy children with a single identified thrombophilic defect appears to be very low. Common triggering conditions for VTE in thrombophilic adults do not seem to increase the thrombotic risk in children carrying the same inherited defect. Accordingly, screening for thrombophilia in otherwise healthy children younger than 15 years who belong to families with inherited defects predisposing to thrombosis seems unjustified.

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