Hypoxic ventilatory response after rocuronium‐induced partial neuromuscular blockade in men with obstructive sleep apnoea

Anaesthesia ◽  
2020 ◽  
Vol 75 (3) ◽  
pp. 338-347 ◽  
Author(s):  
E. Christensson ◽  
A. Ebberyd ◽  
A. Hårdemark Cedborg ◽  
Å. Lodenius ◽  
Å. Österlund Modalen ◽  
...  
Keyword(s):  
Neuromuscular Blockade ◽  
Obstructive Sleep Apnoea ◽  
Ventilatory Response ◽  
Sleep Apnoea ◽  
Hypoxic Ventilatory Response ◽  
Obstructive Sleep ◽  
Partial Neuromuscular Blockade

Sleep-disordered breathing and ventilatory chemosensitivity in first ischaemic stroke patients: a prospective cohort study

Thorax ◽  
2021 ◽  
pp. thoraxjnl-2021-218003
Author(s):  
Sébastien Baillieul ◽  
Sébastien Bailly ◽  
Olivier Detante ◽  
Sarah Alexandre ◽  
Marie Destors ◽  
...  
Keyword(s):  
Ischaemic Stroke ◽  
Obstructive Sleep Apnoea ◽  
Sleep Disordered Breathing ◽  
Ventilatory Response ◽  
Sleep Apnoea ◽  
Stroke Patients ◽  
Central Sleep Apnoea ◽  
Hypercapnic Ventilatory Response ◽  
Obstructive Sleep ◽  
First Time

RationaleSleep-disordered breathing (SDB) is highly prevalent after stroke. The clinical and ventilatory chemosensitivity characteristics of SDB, namely obstructive, central and coexisting obstructive and central sleep apnoea (coexisting sleep apnoea) following stroke are poorly described.ObjectiveTo determine the respective clinical and ventilatory chemosensitivity characteristics of SDB at least 3 months after a first ischaemic stroke.MethodsCross-sectional analysis of a prospective, monocentric cohort conducted in a university hospital. 380 consecutive stroke or transient ischaemic attack patients were screened between December 2016 and December 2019.Measurements and main resultsFull-night polysomnography, and hypercapnic ventilatory response were performed at a median (Q1; Q3) time from stroke onset of 134.5 (97.0; 227.3) days. 185 first-time stroke patients were included in the analysis. 94 (50.8%) patients presented no or mild SDB (Apnoea-Hypopnoea Index <15 events/hour of sleep) and 91 (49.2%) moderate to severe SDB, of which 52 (57.1%) presented obstructive sleep apnoea and 39 (42.9%) coexisting or central sleep apnoea. Obstructive sleep apnoea patients significantly differed regarding their clinical presentation from patients with no or mild SDB, whereas there was no difference with coexisting and central sleep apnoea patients. The latter presented a higher frequency of cerebellar lesions along with a heightened hypercapnic ventilatory response compared with no or mild SDB patients.ConclusionSDB in first-time stroke patients differ in their presentation by their respective clinical traits and ventilatory chemosensitivity characteristics. The heightened hypercapnic ventilatory response in coexisting and central sleep apnoea stroke patients may orientate them to specific ventilatory support.

Ventilatory response amongst patients with obstructive sleep apnoea

2016 ◽  
Author(s):  
Christopher Earing ◽  
Damian Mckeon ◽  
Jonathan Moore ◽  
Hans-Peter Kubis
Keyword(s):  
Obstructive Sleep Apnoea ◽  
Ventilatory Response ◽  
Sleep Apnoea ◽  
Obstructive Sleep

scholarly journals The influence of gender and upper airway resistance on the ventilatory response to arousal in obstructive sleep apnoea in humans

2004 ◽  
Vol 558 (3) ◽  
pp. 993-1004 ◽  
Author(s):  
Amy S. Jordan ◽  
R. Doug McEvoy ◽  
Jill K. Edwards ◽  
Karen Schory ◽  
Chang-Kook Yang ◽  
...  
Keyword(s):  
Obstructive Sleep Apnoea ◽  
Airway Resistance ◽  
Ventilatory Response ◽  
Upper Airway ◽  
Sleep Apnoea ◽  
Upper Airway Resistance ◽  
Obstructive Sleep

The severity of obstructive sleep apnoea does not influence ambient IGF-I levels

2017 ◽  
Author(s):  
Julie Lynch ◽  
Nikolaos Kyriakakis ◽  
Mark Elliott ◽  
Dipansu Ghosh ◽  
Mitchell Nix ◽  
...  
Keyword(s):  
Obstructive Sleep Apnoea ◽  
Sleep Apnoea ◽  
Obstructive Sleep ◽  
Igf I

Requirement of staged interventions in a complex case of Acromegaly and Obstructive Sleep Apnoea

2020 ◽  
Author(s):  
Mili Dhar ◽  
Jennifer Elias ◽  
Benjamin Field ◽  
Sunil Zachariah ◽  
Julian Emmanuel
Keyword(s):  
Obstructive Sleep Apnoea ◽  
Sleep Apnoea ◽  
Complex Case ◽  
Obstructive Sleep

Obstructive sleep apnoea is highly prevalent in a bariatric surgical population

2020 ◽  
Author(s):  
Rachel Agius ◽  
Claudia Coelho ◽  
James Crane ◽  
Piya Sen Gupta ◽  
Barbara McGowan
Keyword(s):  
Obstructive Sleep Apnoea ◽  
Sleep Apnoea ◽  
Obstructive Sleep
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