Bet v 1 and other birch allergens are more resistant to proteolysis and more abundant than other birch pollen proteins

Allergy ◽  
2022 ◽  
Author(s):  
Aurora Cabrera ◽  
Alexander C.Y. Foo ◽  
Michael C. Fitzgerald ◽  
Geoffrey A. Mueller
Keyword(s):  
Birch Pollen ◽  
Bet V 1

scholarly journals Bet v 1 from birch pollen is a hypoallergen with vitamin D3 in the pocket

Allergy ◽  
2021 ◽  
Author(s):  
Karin Hufnagl ◽  
Livia Kromp ◽  
Rodolfo Bianchini ◽  
Sheriene Moussa Afify ◽  
Markus Wiederstein ◽  
...  
Keyword(s):  
Vitamin D3 ◽  
Birch Pollen ◽  
Bet V 1

scholarly journals Caveolar transport through nasal epithelium of birch pollen allergen Bet v 1 in allergic patients

2009 ◽  
Vol 124 (1) ◽  
pp. 135-142.e21 ◽  
Author(s):  
Sakari Joenväärä ◽  
Pirkko Mattila ◽  
Jutta Renkonen ◽  
Antti Mäkitie ◽  
Sanna Toppila-Salmi ◽  
...  
Keyword(s):  
Birch Pollen ◽  
Pollen Allergen ◽  
Nasal Epithelium ◽  
Bet V 1 ◽  
Birch Pollen Allergen

scholarly journals Genetic Variants in CHIA and CHI3L1 Are Associated with the IgE Response to the Ascaris Resistance Marker ABA-1 and the Birch Pollen Allergen Bet v 1

PLoS ONE ◽  
2016 ◽  
Vol 11 (12) ◽  
pp. e0167453 ◽  
Author(s):  
Nathalie Acevedo ◽  
Adriana Bornacelly ◽  
Dilia Mercado ◽  
Per Unneberg ◽  
Irene Mittermann ◽  
...  
Keyword(s):  
Genetic Variants ◽  
Birch Pollen ◽  
Pollen Allergen ◽  
Resistance Marker ◽  
Bet V 1 ◽  
Birch Pollen Allergen ◽  
Ige Response

Bet v 1 and its Homologs: Triggers of Tree-Pollen Allergy and Birch Pollen-Associated Cross-Reactions

2017 ◽  
pp. 21-42 ◽  
Author(s):  
J. Kleine-Tebbe ◽  
B. K. Ballmer-Weber ◽  
H. Breiteneder ◽  
S. Vieths
Keyword(s):  
Birch Pollen ◽  
Pollen Allergy ◽  
Tree Pollen ◽  
Cross Reactions ◽  
Bet V 1

Quality and potency profile of eight recombinant isoallergens, largely mimicking total Bet v 1‐specific IgE binding of birch pollen

2019 ◽  
Vol 49 (5) ◽  
pp. 712-723 ◽  
Author(s):  
Christian Seutter von Loetzen ◽  
Andreas Reuter ◽  
Jelena Spiric ◽  
Thomas Schulenborg ◽  
Iris Bellinghausen ◽  
...  
Keyword(s):  
Birch Pollen ◽  
Specific Ige ◽  
Bet V 1 ◽  
Ige Binding

scholarly journals Agaricus blazei-Based Mushroom Extract Supplementation to Birch Allergic Blood Donors: A Randomized Clinical Trial

Nutrients ◽  
2019 ◽  
Vol 11 (10) ◽  
pp. 2339 ◽  
Author(s):  
Faiza Mahmood ◽  
Geir Hetland ◽  
Ivo Nentwich ◽  
Mohammad Reza Mirlashari ◽  
Reza Ghiasvand ◽  
...  
Keyword(s):  
Placebo Group ◽  
Pollen Season ◽  
Blood Donors ◽  
Birch Pollen ◽  
Specific Ige ◽  
Basophil Activation ◽  
Pollen Extract ◽  
Agaricus Blazei ◽  
Oral Supplementation ◽  
Bet V 1

Since Agaricus blazei Murill (AbM) extract reduced specific IgE and ameliorated a skewed Th1/Th2 balance in a mouse allergy model, it was tested in blood donors with self-reported, IgE-positive, birch pollen allergy and/or asthma. Sixty recruited donors were randomized in a placebo-controlled, double-blinded study with pre-seasonal, 7-week, oral supplementation with the AbM-based extract AndosanTM. Before and after the pollen season, questionnaires were answered for allergic rhino-conjunctivitis, asthma, and medication; serum IgE was measured, and Bet v 1-induced basophil activation was determined by CD63 expression. The reported general allergy and asthma symptoms and medication were significantly reduced in the AbM compared to the placebo group during pollen season. During the season, there was significant reduction in specific IgE anti-Bet v 1 and anti-t3 (birch pollen extract) levels in the AbM compared with the placebo group. While the maximal allergen concentrations needed for eliciting basophil activation before the season, changed significantly in the placebo group to lower concentrations (i.e., enhanced sensitization) after the season, these concentrations remained similar in the AndosanTM AbM extract group. Hence, the prophylactic effect of oral supplementation before the season with the AbM-based AndosanTM extract on aeroallergen-induced allergy was associated with reduced specific IgE levels during the season and basophils becoming less sensitive to allergen activation.

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