scholarly journals EAACI position paper on the clinical use of the bronchial allergen challenge: unmet needs and research priorities

Allergy ◽  
2022 ◽  
Author(s):  
Ioana Agache ◽  
Dario Antolin‐Amerigo ◽  
Frederic de Blay ◽  
Cristina Boccabella ◽  
Cristiano Caruso ◽  
...  
Keyword(s):  
Unmet Needs ◽  
Allergen Challenge ◽  
Research Priorities ◽  
Position Paper ◽  
Clinical Use ◽  
Bronchial Allergen Challenge

Changes in Exhaled Nitric Oxide Levels After Bronchial Allergen Challenge

Lung ◽  
2012 ◽  
Vol 190 (2) ◽  
pp. 209-214 ◽  
Author(s):  
María Pedrosa ◽  
Pilar Barranco ◽  
Valentín López-Carrasco ◽  
Santiago Quirce
Keyword(s):  
Nitric Oxide ◽  
Allergen Challenge ◽  
Exhaled Nitric Oxide ◽  
Bronchial Allergen Challenge

scholarly journals The needs of patients with psoriatic arthritis and psoriasis in the Pan-American region

2021 ◽  
Author(s):  
Adriana Denisse García Coello
Keyword(s):  
Psoriatic Arthritis ◽  
Unmet Needs ◽  
Position Paper ◽  
Psoriatic Disease ◽  
Pan American ◽  
Pan American Region ◽  
American Region

PANLAR collected feedback and recommendations from patients and expert rheumatologists on the unmet needs of those diagnosed with psoriatic disease and set them down in a position paper

scholarly journals Clinical use of Convalescent Plasma in the COVID‐19 pandemic: a transfusion‐focussed gap analysis with recommendations for future research priorities

Vox Sanguinis ◽  
2020 ◽  
Author(s):  
Arwa Z. Al‐Riyami ◽  
Richard Schäfer ◽  
Karin Berg ◽  
Evan M. Bloch ◽  
Lise J. Estcourt ◽  
...  
Keyword(s):  
Gap Analysis ◽  
Research Priorities ◽  
Future Research ◽  
Clinical Use

Analysis of T-cell activation after bronchial allergen challenge in patients with atopic asthma☆☆☆★★★

1998 ◽  
Vol 101 (5) ◽  
pp. 699-708 ◽  
Author(s):  
Maria L. Lara-Marquez ◽  
Aaron Deykin ◽  
Stephen Krinzman ◽  
James Listman ◽  
Elliot Israel ◽  
...  
Keyword(s):  
T Cell ◽  
T Cell Activation ◽  
Cell Activation ◽  
Allergen Challenge ◽  
Atopic Asthma ◽  
Bronchial Allergen Challenge

Regulation of CCR4 expression after segmental bronchial allergen challenge in atopic asthmatics

2002 ◽  
Vol 109 (1) ◽  
pp. S41-S41 ◽  
Author(s):  
Stephen Durham ◽  
Kayhan T Nouri-Aria ◽  
Duncan R Wilson ◽  
Mikila R Jacobson ◽  
Eva M Varga ◽  
...  
Keyword(s):  
Allergen Challenge ◽  
Bronchial Allergen Challenge

Frequencies of circulating CD4+CD25+CD127low cells in atopics are altered by bronchial allergen challenge

2008 ◽  
Vol 38 (3) ◽  
pp. 201-204 ◽  
Author(s):  
M. Moniuszko ◽  
K. Kowal ◽  
S. Zukowski ◽  
M. Dabrowska ◽  
A. Bodzenta-Lukaszyk
Keyword(s):  
Allergen Challenge ◽  
Bronchial Allergen Challenge

scholarly journals Knowledge gaps and research priorities in tuberculous meningitis

2019 ◽  
Vol 4 ◽  
pp. 188
Author(s):  
James A Seddon ◽  
Robert Wilkinson ◽  
Reinout van Crevel ◽  
Anthony Figaji ◽  
Guy E Thwaites ◽  
...  
Keyword(s):  
Tuberculous Meningitis ◽  
Unmet Needs ◽  
Research Priorities ◽  
Future Research ◽  
Knowledge Gaps ◽  
Fatal Disease ◽  
Writing Group ◽  
Recent Meeting ◽  
Immunodeficiency Virus ◽  
Research Consortium

Tuberculous meningitis (TBM) is the most severe and disabling form of tuberculosis (TB), accounting for around 1-5% of the global TB caseload, with mortality of approximately 20% in children and up to 60% in persons co-infected with human immunodeficiency virus even in those treated. Relatively few centres of excellence in TBM research exist and the field would therefore benefit from greater co-ordination, advocacy, collaboration and early data sharing. To this end, in 2009, 2015 and 2019 we convened the TBM International Research Consortium, bringing together approximately 50 researchers from five continents. The most recent meeting took place on 1st and 2nd March 2019 in Lucknow, India. During the meeting, researchers and clinicians presented updates in their areas of expertise, and additionally presented on the knowledge gaps and research priorities in that field. Discussion during the meeting was followed by the development, by a core writing group, of a synthesis of knowledge gaps and research priorities within seven domains, namely epidemiology, pathogenesis, diagnosis, antimicrobial therapy, host-directed therapy, critical care and implementation science. These were circulated to the whole consortium for written input and feedback. Further cycles of discussion between the writing group took place to arrive at a consensus series of priorities. This article summarises the consensus reached by the consortium concerning the unmet needs and priorities for future research for this neglected and often fatal disease.

scholarly journals Precision Medicine in House Dust Mite-Driven Allergic Asthma

2020 ◽  
Vol 9 (12) ◽  
pp. 3827
Author(s):  
Ibon Eguiluz-Gracia ◽  
Francisca Palomares ◽  
Maria Salas ◽  
Almudena Testera-Montes ◽  
Adriana Ariza ◽  
...  
Keyword(s):  
Allergic Asthma ◽  
House Dust ◽  
Inhaled Corticosteroids ◽  
Current Knowledge ◽  
Allergen Challenge ◽  
Pharmaceutical Products ◽  
House Dust Mites ◽  
Dust Mites ◽  
Bronchial Allergen Challenge

House dust mites (HDMs) are the allergenic sources most frequently involved in airway allergy. Nevertheless, not every sensitized patient develops respiratory symptoms upon exposure to HDM, and there is a clinical need to differentiate allergic asthmatics (AAs) from atopic non-allergic asthmatics with HDM sensitization. This differentiation sometimes requires in vivo provocations like the bronchial allergen challenge (BAC). Interestingly, recent data demonstrate that non-atopic patients with asthma can also develop positive BAC results. This novel phenotype has been termed local allergic asthma (LAA). The interest in identifying the allergic triggers of asthma resides in the possibility of administering allergen immunotherapy (AIT). AIT is a disease-modifying intervention, the clinical benefit of which persists after therapy discontinuation. Recently, new modalities of sublingual tablets of HDM immunotherapy registered as pharmaceutical products (HDM-SLIT tablets) have become commercially available. HDM-SLIT tablets have demonstrated a robust effect over critical asthma parameters (dose of inhaled corticosteroids, exacerbations, and safety), thus being recommended by international guidelines for patients with HDM-driven AA. In this review, we will summarize the current knowledge on the phenotype and endotype of HDM-driven AA, and LAA, address the difficulties for BAC implementation in the clinic, and discuss the effects of AIT in AA and LAA.

Sign in / Sign up

Export Citation Format

Share Document