Questionnaire as an alternative ofskin prick tests to differentiate allergic from non‐allergic rhinitis in epidemiological studies

Allergy ◽  
2021 ◽  
Author(s):  
Marine Savouré ◽  
Jean Bousquet ◽  
Emilie Burte ◽  
Jocelyne Just ◽  
Isabelle Pin ◽  
...  
Keyword(s):  
Allergic Rhinitis ◽  
Epidemiological Studies ◽  
Non Allergic Rhinitis

scholarly journals Reflection of modern concepts of therapy in the treatment of allergic diseases of the nose and paranasal sinuses

2020 ◽  
pp. 78-84
Author(s):  
S. V. Ryazantsev ◽  
S. S. Pavlova
Keyword(s):  
Allergic Rhinitis ◽  
Fluticasone Propionate ◽  
Paranasal Sinuses ◽  
Financial Burden ◽  
General Structure ◽  
Allergic Diseases ◽  
Epidemiological Studies ◽  
Modern Medicine ◽  
Nose And Paranasal Sinuses ◽  
Non Allergic Rhinitis

The article highlights the urgent problem of modern medicine - allergic diseases. Over the past decades, there has been a significant increase in the prevalence of this pathology, the share of which in the general structure of the incidence of the population remains high to this day. The statistics are staggering. According to various sources, various manifestations of allergies affect from 10% to 40% of the world’s population. According to conservative estimates, more than 500 million people in the world. According to epidemiological studies, the amount of atopy is growing by 5-6% every year. The disease has a huge impact on the quality of life of the patient. Needless to say, an allergic disease can be accompanied by complications, including life-threatening. The big financial burden on the budget of our country is the economic costs of combating allergies and its complications. Therefore, the treatment of this nasology is one of the key issues both in the global and in Russian healthcare.Intranasal (topical) corticosteroids (IKS) are the drug of choice in the treatment of patients diagnosed with allergic rhinitis (AR). However, ICS are widely used in clinical practice and in the treatment of other diseases of the nose and paranasal sinuses. Depending on the nature of the pathological process, the duration of the drug can vary widely: from two weeks to several months or years. The purpose of this work is to systematize relevant publications and analyze possible uses for this group of drugs. The article reflects the issues of epidemiology, etiopathogenesis of allergic rhinitis. Consistently considered modern methods of treatment, in particular the use of (ICS) in therapy regimens. The results of international multicenter randomized controlled clinical trials are presented, the purpose of which was to determine and evaluate the efficacy and tolerability of ICS, in particular fluticasone propionate. It is concluded that fluticasone propionate is a modern and effective agent for the pathogenetic treatment of patients with not only allergic but also non-allergic rhinitis and can be recommended in the modern treatment regimen for both allergic and non-allergic rhinitis.

Effect of a moustache on nasal Staphylococcus aureus colonisation and nasal cytology results in men

2015 ◽  
Vol 129 (2) ◽  
pp. 155-158 ◽  
Author(s):  
E Soylu ◽  
I Orhan ◽  
A Cakir ◽  
A Istanbullu ◽  
G Altin ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Allergic Rhinitis ◽  
Nasal Cavity ◽  
Control Group ◽  
Study Group ◽  
Left Nasal Cavity ◽  
Adult Men ◽  
Nasal Cytology ◽  
Non Allergic Rhinitis

AbstractObjective:This study compared the results of nasal Staphylococcus aureus carriage and nasal cytology in men with and without a moustache.Methods:The study group comprised 118 adult men with a moustache, and the control group consisted of 123 adult men without a moustache. Samples were taken from the participants' right nasal cavity for cytology and from the left nasal cavity for microbiology.Results:The results for S aureus were positive in 19.5 per cent (n = 23) of participants with a moustache and in 20.3 per cent (n = 25) of men without a moustache. This difference was not significant (p > 0.05). However, nasal cytology revealed rich eosinophil clusters in participants with a moustache.Conclusion:The presence or absence of a moustache had no effect on nasal S aureus colonisation. However, further research is needed to understand whether the presence of a moustache increases the risk of allergic or non-allergic rhinitis.

Comparison of efficacy and tolerability of oral desloratadine, rupatadine and ketotifen in seasonal allergic rhinitis

2021 ◽  
Vol 4 (3) ◽  
pp. 106-114
Author(s):  
Syed Khadeer ◽  
B Jagannath
Keyword(s):  
Allergic Rhinitis ◽  
Adverse Events ◽  
Nasal Congestion ◽  
Primary Outcome Measure ◽  
Nasal Symptom ◽  
Secondary Outcome ◽  
Open Label ◽  
Non Allergic Rhinitis ◽  
The Individual ◽  
Change In Mean

Rhinitis is inflammation of nasal mucosa which characteristically presents as running nose, blocked nose, itching on nose or sneezing. Allergic rhinitis is more common than non-allergic rhinitis. Anti-histamines are the mainstay of SAR treatment. Desloratadine, rupatadine and ketotifen are the commonly prescribed anti histamines in our region. In this study, we have compared efficacy and tolerability of desloratadine, rupatadine and ketotifen in SAR. This was a prospective, randomized, three arm, open label comparative study of desloratadine, rupatadine and ketotifen in SAR, conducted at Department of ENT, Kempegowda Institute of Medical Sciences, Bangalore; between January 2014 and December 2014. Patients’ severity of SAR symptoms were assessed by TNSS, QoL was measured using Medical Outcomes Study questionnaire (SF-12). SF-12 was administered at the start of study and then at the end of study. Adverse effects were monitored during clinical examination at each visit. Study subjects were systemically randomized into three groups – desloratadine (DES), rupatadine (RUP) and ketotifen (KET). Based on the assigned group; desloratadine was given orally in dose of 10mg OD, rupatadine orally 10 mg OD and ketotifen orally 1mg BD. All medications were given for 4 weeks. Follow up was done for all patients every week during treatment period of 4 weeks. The primary outcome measure was change in mean TNSS from baseline; secondary outcome measures were changes in the individual nasal symptom scores, change in the quality of life and tolerability to the study medications. Total 150 patients were recruited for this study, divided into 3 groups. DES and RUP were equally effective but significantly better than KET in improving rhinorrhea, nasal congestion, TNSS and AEC. (p=0.05). All the drugs were equally effective with no statistically significant intergroup difference in improving sneezing, nasal itching and QoL. RUP appeared to have better tolerability as the total number of adverse events were marginally less. DES and RUP are comparatively more effective and faster acting than KET. All the study medications were well tolerated with few mild, self-limiting, transient adverse events requiring no intervention.

scholarly journals Can nasal nitric oxide be a biomarker to differentiate allergic and non-allergic rhinitis?

2021 ◽  
Vol 37 (1) ◽  
Author(s):  
A. F. Kalpaklioglu ◽  
A. Baccioglu ◽  
S. A. Yalim
Keyword(s):  
Nitric Oxide ◽  
Allergic Rhinitis ◽  
Severe Disease ◽  
Female Gender ◽  
Non Invasive ◽  
Nasal Nitric Oxide ◽  
Nasal Symptoms ◽  
Asthma Patients ◽  
Duration Of Disease ◽  
Non Allergic Rhinitis

Abstract Background Nasal nitric oxide (nNO), a noninvasive indicator for eosinophilic airway inflammation, has not been adequately studied in different types of rhinitis. The aim of this study was to compare nNO levels between allergic (AR) and non-allergic rhinitis (NAR). Patients were included based on their chronic nasal symptoms. Total nasal symptoms score (TNSS) were evaluated. nNO was measured transnasally with a flow of 5 ml/s from the nostril with an NO analyzer (NIOX MINO; Aerocrine, Sweden). Results were evaluated as parts per billion (ppb). Results Four hundred forty-three patients (277 F/166 M)—337 with AR (76%) and 106 with NAR (24%)—were assessed. Patients with AR had significantly higher TNSS, more severe disease, and longer duration of disease compared to NAR group. Allergic rhinitis had significantly higher nNO levels than NAR (370 ppb vs 290 ppb) (p = 0.001). Likewise, significant differences were observed in female gender, in patients with BMI ≥ 25 kg/m2 and those without sinusitis between the two groups. When nNO were further evaluated in comorbid asthma, patients with AR w/o asthma had the highest TNSS and had significantly higher nNO level (p < 0.001). NAR+A group, with the longest duration of rhinitis, was significantly older and had the lowest nNO level (p < 0.001). Conclusions This study showed that nNO levels were significantly higher in AR patients than NAR. Although there is no recommended standard threshold for nNO, this study confirmed the utility of nNO in differentiating AR and NAR in addition to its known fast and non-invasive advantages.

scholarly journals Non-Allergic Rhinitis with Eosinophils and Mast Cells Constitutes a New Severe Nasal Disorder

2008 ◽  
Vol 21 (2) ◽  
pp. 325-331 ◽  
Author(s):  
M. Gelardi ◽  
A. Maselli Del Giudice ◽  
M.L. Fiorella ◽  
R. Fiorella ◽  
C. Russo ◽  
...  
Keyword(s):  
Allergic Rhinitis ◽  
Mast Cells ◽  
Non Allergic Rhinitis

Clinical Evaluation Of Patients With Non-Allergic Rhinitis

2008 ◽  
Vol 121 (2) ◽  
pp. S129-S129
Author(s):  
P CAMPO ◽  
C RONDON ◽  
M TORRES ◽  
J ROMERO ◽  
D RUIZ ◽  
...  
Keyword(s):  
Allergic Rhinitis ◽  
Clinical Evaluation ◽  
Non Allergic Rhinitis

Intranasal corticosteroids for non-allergic rhinitis

2013 ◽  
Author(s):  
Artur Gevorgyan ◽  
Christine Segboer ◽  
Supinda Chusakul ◽  
Jesada Kanjanaumporn ◽  
Songklot Aeumjaturapat ◽  
...  
Keyword(s):  
Allergic Rhinitis ◽  
Intranasal Corticosteroids ◽  
Non Allergic Rhinitis

Non-infectious, non-allergic rhinitis

2018 ◽  
Author(s):  
Luke Reid
Keyword(s):  
Allergic Rhinitis ◽  
Outcome Measures ◽  
Non Allergic Rhinitis

This chapter discusses Sanico and Togias’s paper on non-infectious, non-allergic rhinitis including the design of the study (outcome measures, results, conclusions, and a critique).

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