Quality of life of children aged 8‐12 years undergoing food allergy oral immunotherapy: Child and parent perspective

Allergy ◽  
2020 ◽  
Vol 75 (10) ◽  
pp. 2623-2632 ◽  
Author(s):  
Na'ama Epstein‐Rigbi ◽  
Michael R. Goldberg ◽  
Michael B. Levy ◽  
Liat Nachshon ◽  
Arnon Elizur
Keyword(s):  
Quality Of Life ◽  
Food Allergy ◽  
Oral Immunotherapy ◽  
Parent Perspective

The Effects of Peanut Oral Immunotherapy on Food Allergy Related Quality of Life

2012 ◽  
Vol 129 (2) ◽  
pp. AB29 ◽  
Author(s):  
J.M. Factor ◽  
M.R. Lester ◽  
L.M. Mendelson ◽  
J.O. Lee ◽  
J. Sproviero ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Food Allergy ◽  
Oral Immunotherapy ◽  
Related Quality

scholarly journals Impact of Oral Immunotherapy on Food Allergy Related Quality of Life in Teenagers

2020 ◽  
Vol 145 (2) ◽  
pp. AB136
Author(s):  
Justin Greiwe ◽  
William Lavery ◽  
Jonathan Bernstein ◽  
Umesh Singh
Keyword(s):  
Quality Of Life ◽  
Food Allergy ◽  
Oral Immunotherapy ◽  
Related Quality

scholarly journals Weighing the benefits and risks of oral immunotherapy in clinical practice

2021 ◽  
Vol 42 (2) ◽  
pp. 118-123
Author(s):  
Aikaterini Anagnostou
Keyword(s):  
Quality Of Life ◽  
Food Allergy ◽  
The United States ◽  
Oral Immunotherapy ◽  
Food Allergies ◽  
Allergic Reactions ◽  
Immune Modulators ◽  
Significant Burden ◽  
Working Together

Food allergies are common and affect 6‐8% of children in the United States; they pose a significant burden on the quality of life of children with allergy and their caregivers due to multiple daily restrictions. Despite the recommended dietary avoidance, reactions tend to occur due to unintentional exposure to the allergenic food trigger. Fear of accidental ingestions with potentially severe reactions, including anaphylaxis and death, creates anxiety in individuals with food allergy. Oral immunotherapy has emerged as a form of active and potentially disease-modifying treatment for common food allergies encountered in childhood. The efficacy of oral immunotherapy is high, with the majority of participants achieving desensitization and, as a result, protection from trace exposures and improved quality of life. The main risk of oral immunotherapy consists of allergic reactions to treatment. In general, rates of allergic reactions and anaphylaxis are reported to be higher in individuals pursuing therapy options, but most subjects who undergo oral immunotherapy will likely experience mild or moderate reactions during treatment. Adverse events tend to reduce in both frequency and number in the maintenance period. The use of immune modulators alongside oral immunotherapy has been suggested, with the aim to improve efficacy and safety, and to facilitate the overall process. It is evident that the landscape of food allergy management is changing and that the future looks brighter, with different options emerging over time. The process of how to choose the appropriate option becomes a discussion between the clinician and the patient, which involves a joint review of the current medical evidence but also the patient's preference for balancing particular attributes of the treatment. By working together, providers and patients will ensure achievement of the best possible outcome for children with food allergies.

scholarly journals Oral Immunotherapy for Food-Allergic Children: A Pro-Con Debate

2021 ◽  
Author(s):  
Francesca Mori ◽  
Mattia Giovannini ◽  
Simona Barni ◽  
Rodrigo Jiménez-Saiz ◽  
Daniel Munblit ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Clinical Trials ◽  
Food Allergy ◽  
Meta Analysis ◽  
Scientific Evidence ◽  
Standard Of Care ◽  
Oral Immunotherapy ◽  
Patient Reported

The prevalence of food allergy has increased in recent years, especially in children. Food allergen avoidance and symptomatic drugs in case of an allergic reaction remain the standard of care in food allergy. Nevertheless, increasing attention has been given to the possibility to treat food allergy, through immunotherapy, particularly oral immunotherapy (OIT). Several OIT protocols and clinical trials have been published. Most of them focus on children allergic to milk, egg, or peanuts, although recent studies developed protocols for other foods, such as wheat and different nuts. OIT efficacy in randomized controlled trials is usually evaluated as the possibility for patients to achieve desensitization, while the issue of a possible long-term sustained unresponsiveness has not been completely addressed. Here, we evaluated current OIT knowledge, focusing on the results of clinical trials and current guidelines. Specifically, we wanted to highlight what is known in terms of OIT efficacy and effectiveness, safety, and impact on quality of life. For each aspect, we reported the pros and the cons, inferable from published literature. In conclusion, even though many protocols, reviews and meta-analysis have been published on this topic, OIT remains a controversial therapy and no definitive generalized conclusion may be drawn so far. It should be an option provided by specialized teams, when both patients and their families are prone to adhere to the proposed protocol. Efficacy, long-term effectiveness, possible role of adjuvant therapies, risk of severe reactions including anaphylaxis or eosinophilic esophagitis, and impact on the quality of life of both children and caregivers are all aspects that should be discussed before starting OIT. Future studies are needed to provide firm clinical and scientific evidence, which should also consider patient reported outcomes.

scholarly journals Quality of Life in Patients during Oral Immunotherapy for Food Allergy

2016 ◽  
Vol 137 (2) ◽  
pp. AB255
Author(s):  
Na'ama Epstein Rigbi ◽  
Yitzhak Katz ◽  
Michael R. Goldberg ◽  
Michael B. Levy ◽  
Liat Nachshon ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Food Allergy ◽  
Oral Immunotherapy

Changes in patient quality of life during oral immunotherapy for food allergy

Allergy ◽  
2017 ◽  
Vol 72 (12) ◽  
pp. 1883-1890 ◽  
Author(s):  
N. Epstein Rigbi ◽  
M. R. Goldberg ◽  
M. B. Levy ◽  
L. Nachshon ◽  
K. Golobov ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Food Allergy ◽  
Oral Immunotherapy

scholarly journals Oral Immunotherapy for Food-Allergic Children: A Pro-Con Debate

2021 ◽  
Vol 12 ◽  
Author(s):  
Francesca Mori ◽  
Mattia Giovannini ◽  
Simona Barni ◽  
Rodrigo Jiménez-Saiz ◽  
Daniel Munblit ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Clinical Trials ◽  
Food Allergy ◽  
Meta Analysis ◽  
Scientific Evidence ◽  
Standard Of Care ◽  
Oral Immunotherapy ◽  
Patient Reported

The prevalence of food allergy has increased in recent years, especially in children. Allergen avoidance, and drugs in case of an allergic reaction, remains the standard of care in food allergy. Nevertheless, increasing attention has been given to the possibility to treat food allergy, through immunotherapy, particularly oral immunotherapy (OIT). Several OIT protocols and clinical trials have been published. Most of them focus on children allergic to milk, egg, or peanut, although recent studies developed protocols for other foods, such as wheat and different nuts. OIT efficacy in randomized controlled trials is usually evaluated as the possibility for patients to achieve desensitization through the consumption of an increasing amount of a food allergen, while the issue of a possible long-term sustained unresponsiveness has not been completely addressed. Here, we evaluated current pediatric OIT knowledge, focusing on the results of clinical trials and current guidelines. Specifically, we wanted to highlight what is known in terms of OIT efficacy and effectiveness, safety, and impact on quality of life. For each aspect, we reported the pros and the cons, inferable from published literature. In conclusion, even though many protocols, reviews and meta-analysis have been published on this topic, pediatric OIT remains a controversial therapy and no definitive generalized conclusion may be drawn so far. It should be an option provided by specialized teams, when both patients and their families are prone to adhere to the proposed protocol. Efficacy, long-term effectiveness, possible role of adjuvant therapies, risk of severe reactions including anaphylaxis or eosinophilic esophagitis, and impact on the quality of life of both children and caregivers are all aspects that should be discussed before starting OIT. Future studies are needed to provide firm clinical and scientific evidence, which should also consider patient reported outcomes.

Medical clown support is associated with better quality of life of children with food allergy starting oral immunotherapy

2021 ◽  
Author(s):  
Naama Epstein Rigbi ◽  
Naama Schwartz ◽  
Michael R Goldberg ◽  
Michael B Levy ◽  
Liat Nachshon ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Food Allergy ◽  
Oral Immunotherapy ◽  
Medical Clown

Changes in Patient Quality of Life During Oral Immunotherapy for Food Allergy

PEDIATRICS ◽  
2018 ◽  
Vol 142 (Supplement 4) ◽  
pp. S242.2-S243
Author(s):  
Salma Bahreinian ◽  
Elinor Simons
Keyword(s):  
Quality Of Life ◽  
Food Allergy ◽  
Oral Immunotherapy
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