Impact of immunotherapy on quality of life in patients with house dust mite allergic rhinitis

Allergy ◽  
2020 ◽  
Vol 75 (7) ◽  
pp. 1783-1785
Author(s):  
Daniel Pedregal‐Mallo ◽  
Esteban Pacheco ◽  
Juan Pablo Rodrigo ◽  
Jose Luis Llorente ◽  
Cesar Alvarez‐Marcos
Keyword(s):  
Quality Of Life ◽  
Allergic Rhinitis ◽  
House Dust ◽  
House Dust Mite ◽  
Dust Mite

Sublingual immunotherapy in patients with house dust mite allergic rhinitis: prospective study of clinical outcomes over a two-year period

2016 ◽  
Vol 130 (3) ◽  
pp. 272-277 ◽  
Author(s):  
J Y Soh ◽  
M Thalayasingam ◽  
S Ong ◽  
E X L Loo ◽  
L P Shek ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Allergic Rhinitis ◽  
House Dust ◽  
House Dust Mite ◽  
Sublingual Immunotherapy ◽  
Nasal Symptom ◽  
Medication Usage ◽  
Dust Mite ◽  
Symptom Scores

AbstractBackground:Sublingual immunotherapy in patients with allergic rhinitis sensitised to house dust mites is safe, but its efficacy is controversial and sublingual immunotherapy withBlomia tropicalishas not yet been studied. This study sought to evaluate the efficacy of sublingual immunotherapy with house dust mite extract in children and adults with house dust mite allergic rhinitis over a period of two years.Methods:A prospective observational study was conducted of children and adults diagnosed with house dust mite allergic rhinitis who were treated with sublingual immunotherapy from 2008 to 2012. Total Nasal Symptom Scores, Mini Rhinoconjunctivitis Quality of Life scores and medication usage scores were assessed prospectively.Results:Thirty-nine patients, comprising 24 children and 15 adults, were studied. Total Nasal Symptom Scores and Mini Rhinoconjunctivitis Quality of Life scores dropped significantly at three months into therapy, and continued to improve. Medication usage scores improved at one year into immunotherapy.Conclusion:Sublingual immunotherapy with house dust mite extracts, includingB tropicalis, is efficacious as a treatment for patients with house dust mite allergic rhinitis.

scholarly journals Clinical effectiveness of house dust mite immunotherapy in mono- versus poly-sensitised patients with allergic rhinitis: a systematic review and meta-analysis

2021 ◽  
Vol 0 (0) ◽  
pp. 0-0
Author(s):  
J.Y. Kim ◽  
D. Hwang ◽  
M. Jang ◽  
C.S. Rhee ◽  
D.H. Han
Keyword(s):  
Quality Of Life ◽  
Systematic Review ◽  
Allergic Rhinitis ◽  
House Dust ◽  
House Dust Mite ◽  
Meta Analysis ◽  
Clinical Effectiveness ◽  
Nasal Symptom ◽  
Dust Mite

Selecting an appropriate allergen-specific immunotherapy (AIT) regimen for polysensitised allergic rhinitis (AR) patients is challenging for clinicians. Although previous studies showed comparable effectiveness of single-allergen AIT with house dust mite (HDM) extract between monosensitised and polysensitised AR patients, there is no systematic review and meta-analysis demonstrating the comparable effectiveness of HDM AIT. In this meta-analysis, we analysed nine studies to compare the clinical effectiveness of HDM AIT. The primary outcome was nasal symptom score and secondary outcomes were medication and quality of life scores. The changes in nasal symptom score after HDM AIT did not significantly differ between monosensitised and polysensitised patients. The clinical effectiveness of HDM AIT regarding medication and quality of life score was not significantly different between monosensitised and polysensitised patients). In conclusion, single-allergen AIT with HDM extract showed comparable clinical effectiveness between polysensitised and monosensitised patients with AR.

scholarly journals Quality of life improvement after a three-year course of sublingual immunotherapy in patients with house dust mite and grass pollen induced allergic rhinitis: results from real-life

2017 ◽  
Vol 15 (1) ◽  
Author(s):  
Silviya Mihaylova Novakova ◽  
Maria Toncheva Staevska ◽  
Plamena Ivanova Novakova ◽  
Manuela Dimitrova Yoncheva ◽  
Maria Stoykova Bratoycheva ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Allergic Rhinitis ◽  
House Dust ◽  
House Dust Mite ◽  
Grass Pollen ◽  
Sublingual Immunotherapy ◽  
Real Life ◽  
Dust Mite ◽  
Life Improvement

scholarly journals Effect of House Dust Mite SLIT-tablet Treatment on Quality of Sleep in Allergic Rhinitis Patients

2019 ◽  
Vol 143 (2) ◽  
pp. AB286 ◽  
Author(s):  
Henrik Jacobi ◽  
Dorte Rehm ◽  
Hendrik Nolte ◽  
Kristian F. Andersen ◽  
Pascal M. Demoly
Keyword(s):  
Allergic Rhinitis ◽  
House Dust ◽  
House Dust Mite ◽  
Quality Of Sleep ◽  
Dust Mite

The effect of encasings on quality of life in adult house dust mite allergic patients with rhinitis, asthma and/or atopic dermatitis

Allergy ◽  
2005 ◽  
Vol 60 (7) ◽  
pp. 888-893 ◽  
Author(s):  
I. Terreehorst ◽  
H. J. Duivenvoorden ◽  
Z. Tempels-Pavlica ◽  
A. J. Oosting ◽  
J. G. R. Monchy ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Atopic Dermatitis ◽  
House Dust ◽  
House Dust Mite ◽  
Dust Mite

scholarly journals Comparison of a generic and a rhinitis-specific quality-of-life (QOL) instrument in patients with house dust mite allergy: relationship between the SF-36 and Rhinitis QOL Questionnaire

2004 ◽  
Vol 34 (11) ◽  
pp. 1673-1677 ◽  
Author(s):  
I. Terreehorst ◽  
H. J. Duivenvoorden ◽  
Z. Tempels-Pavlica ◽  
A. J. Oosting ◽  
J. G. R. de Monchy ◽  
...  
Keyword(s):  
Quality Of Life ◽  
House Dust ◽  
House Dust Mite ◽  
House Dust Mite Allergy ◽  
Mite Allergy ◽  
Sf 36 ◽  
Dust Mite

scholarly journals Role of IL-22 in Persistent Allergic Airway Diseases Caused by House Dust Mite: A Pilot Study

2020 ◽  
Author(s):  
Laura Tamasauskiene ◽  
Vilte Marija Gintauskiene ◽  
Daina Bastyte ◽  
Brigita Sitkauskiene
Keyword(s):  
Quality Of Life ◽  
House Dust ◽  
House Dust Mite ◽  
Nasal Lavage ◽  
Control Group ◽  
Airway Diseases ◽  
Persistent Allergic Rhinitis ◽  
Dust Mite ◽  
Anti Inflammatory

Abstract Background. Persistent allergic airway diseases cause a great burden worldwide. Their pathogenesis is not clear enough. There is evidence that one of the recently described cytokine interleukin (IL) 22 may be involved in the pathogenesis of these diseases. Scientists argue if this cytokine acts as proinflammatory or anti-inflammatory agent. The aim of this study was to investigate IL-22 level in patients with persistent allergic airway diseases caused by house dust mite (HDM) in comparison with healthy individuals and to evaluate its relationship with IL-13 and IL-10 level, symptoms score and quality of life.Methods. Patients with persistent allergic rhinitis caused by HDM and having symptoms for at least 2 years with or without allergic asthma were involved into the study. Measurements of IL-22, IL-13 and IL-10 and in serum and nasal lavage was performed by ELISA. Questionnaires assessing symptoms severity and quality of life were used.Results. A tendency was observed that IL-22 in serum and nasal lavage was higher in patients with allergic airway diseases compared to control group (14.86 pg/ml vs. 7.04 pg/ml and 2.67 pg/ml vs. 1.28 pg/ml, respectively). Positive statistically significant correlation was estimated between serum IL-22 and serum IL-10 (rs=0.57, p<0.01) and IL-13 (rs=0.44, p<0.05) level. Moreover, positive significant correlation was found between IL-22 in nasal lavage and IL-10 in nasal lavage (rs=0.37, p<0.05). There was a negative statistically significant correlation between serum IL-22 and RQLQ (rs=-0.42, p<0.05).Conclusion. Our study showed a possible anti-inflammatory effect of IL-22 in patients with persistent allergic airway diseases caused by HDM.

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