IL‐6 and IL‐1β expression is increased in autologous serum skin test of patients with chronic spontaneous urticaria

Allergy ◽  
2019 ◽  
Vol 74 (12) ◽  
pp. 2522-2524
Author(s):  
Laurence Montjoye ◽  
Mathilde Choteau ◽  
Anne Herman ◽  
Emilie Hendrickx ◽  
Paméla Chéou ◽  
...  
Keyword(s):  
Skin Test ◽  
Chronic Spontaneous Urticaria ◽  
Autologous Serum ◽  
Autologous Serum Skin Test

scholarly journals Quality of Life Based on Autologous Serum Skin Test Result in Chronic Spontaneous Urticaria Patients

2021 ◽  
Vol 4 (1) ◽  
pp. 24-29
Author(s):  
Mahvira Chow Liana Herman Adil ◽  
Nopriyati Nopriyati ◽  
Desi Oktariana ◽  
Yuli Kurniawati ◽  
Gita Dwi Prasasty
Keyword(s):  
Quality Of Life ◽  
Skin Test ◽  
Outpatient Clinic ◽  
Chronic Spontaneous Urticaria ◽  
Autologous Serum ◽  
Bivariate Analysis ◽  
Female Group ◽  
Cross Sectional ◽  
Autologous Serum Skin Test

Several studies regarding the quality of life of chronic spontaneous urticaria patients based on Autologous Serum Skin Test (ASST) results have shown a variety of results. This study aims to determine the correlation between the quality of life and ASST results in chronic spontaneous urticaria patients at Dermatology and Venereology (DV) Outpatient Clinic of Dr. Mohammad Hoesin Hospital Palembang. This analytic observational study with a cross-sectional design used secondary data in the form of medical records. 76 samples met the inclusion criteria from 110 samples of chronic spontaneous urticaria patients at DV outpatient clinic. The distribution of chronic spontaneous urticaria patients was highest in the 17-25 year age group (23.7%) and the female group (64.5%). The majority of chronic spontaneous urticaria patients had negative ASST results (52.6%). The effect of chronic spontaneous urticaria on the decline in quality of life was mostly moderate (35.5%). The bivariate analysis between DLQI score and ASST results with a value of p = 0.307 or p> 0.05 showed no significant correlation between the quality of life and ASST results.

scholarly journals Association between chronic spontaneous urticaria and thyroid autoimmunity: a case control study from a tertiary care centre

2017 ◽  
Vol 3 (1) ◽  
pp. 64 ◽  
Author(s):  
Olasseri K. Reena Mariyath ◽  
Manikoth P. Binitha ◽  
Vadakke P. Anilakumari ◽  
George Biju ◽  
Pappinisseri K. Nikhila ◽  
...  
Keyword(s):  
Skin Test ◽  
Thyroid Function ◽  
Antibody Level ◽  
Thyroid Autoimmunity ◽  
Chronic Spontaneous Urticaria ◽  
Autologous Serum ◽  
Thyroid Peroxidase ◽  
Thyroid Function Tests ◽  
Autologous Serum Skin Test ◽  
Antibody Levels

<p class="abstract"><strong>Background:</strong> The exact etiology of chronic spontaneous urticaria is unknown in the majority of patients. A subset of chronic spontaneous urticaria can be autoimmune and may be associated with thyroid autoimmunity<span lang="EN-IN">.</span></p><p class="abstract"><strong>Methods:</strong> Serum anti thyroid peroxidase (anti-TPO) antibody level and thyroid function tests (TFT) including triiodothyronine (T3), thyroxine (T4) and thyroid stimulating hormone (TSH) levels were estimated in 100patients with chronic spontaneous urticaria and 50 controls. Autologous serum skin test (ASST) was done in 84 chronic urticaria patients and 21 patients with high anti-TPO antibody.<strong></strong></p><p class="abstract"><strong>Results:</strong> High anti-TPO antibodies and abnormal thyroid function were seen in 24 (24%) patients each. High anti-TPO antibody levels were seen in nine (18%) and abnormal TFT in 11 (22%) controls. Abnormal TSH was seen in 22 patients (22%) and 6 (12%) controls. Autologous serum skin test was positive in 53 patients with chronic spontaneous urticaria. It was positive in 16 and negative in five out of 21 patients with high anti-TPO antibody levels<span lang="EN-IN">. </span></p><p class="abstract"><strong>Conclusions:</strong> Though there was a slight increase in abnormal anti-TPO antibody level and thyroid dysfunction in patients with chronic spontaneous urticaria compared to controls, it was not statistically significant<span lang="EN-IN">.</span></p>

scholarly journals Autologous Serum Skin Test versus Autologous Plasma Skin Test in Patients with Chronic Spontaneous Urticaria

2013 ◽  
Vol 2013 ◽  
pp. 1-6 ◽  
Author(s):  
Aysegul Alpay ◽  
Nilgün Solak Tekin ◽  
Ishak Özel Tekin ◽  
H. Cevdet Altinyazar ◽  
Rafet Koca ◽  
...  
Keyword(s):  
Skin Test ◽  
Chronic Spontaneous Urticaria ◽  
Autologous Serum ◽  
Thyroid Autoantibodies ◽  
Thyroid Function Tests ◽  
Control Groups ◽  
Autologous Plasma ◽  
Autologous Serum Skin Test ◽  
Autoimmune Urticaria ◽  
And Control

Previous studies indicate that 25–45% of chronic urticaria patients have an autoimmune etiology. Autologous serum skin test (ASST) and autologous plasma skin test (APST) are simple tests for diagnosing chronic autoimmune urticaria (CAU). However, there are still some questions about the specificity of these tests. This study consisted of 50 patients with chronic spontaneous urticaria (CSU) and 50 sex- and age-matched healthy individuals aged 18 years, and older. A total of 31 (62%) patients and 5 (10%) control patients had positive ASST; 21 (42%) patients and 3 (6%) control patients had positive APST. Statistically significant differences were noted in ASST and APST positivity between the patient and control groups (ASSTP<0.001; APSTP<0.001). Thirteen (26%) patients and 5 (10%) control patients had antithyroglobulin antibodies or antithyroid peroxidase antibody positivity. No statistically significant differences were noted in thyroid autoantibodies between the patient and control groups (anti-TGP=0.317; anti-TPOP=0.269). We consider that the ASST and APST can both be used asin vivotests for the assessment of autoimmunity in the etiology of CSU and that thyroid autoantibodies should be checked even when thyroid function tests reveal normal results in patients with CSU.

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