Childhood atopic dermatitis-Brain-derived neurotrophic factor correlates with serum eosinophil cationic protein and disease severity

Allergy ◽  
2016 ◽  
Vol 71 (7) ◽  
pp. 1062-1065 ◽  
Author(s):  
R. Fölster-Holst ◽  
E. Papakonstantinou ◽  
U. Rüdrich ◽  
M. Buchner ◽  
H. Pite ◽  
...  
Keyword(s):  
Atopic Dermatitis ◽  
Disease Severity ◽  
Neurotrophic Factor ◽  
Eosinophil Cationic Protein ◽  
Brain Derived Neurotrophic Factor ◽  
Cationic Protein

Relationship of serum brain-derived neurotrophic factor level with other markers of disease severity in patients with atopic dermatitis

2007 ◽  
Vol 122 (2) ◽  
pp. 181-186 ◽  
Author(s):  
Kenji Namura ◽  
Goji Hasegawa ◽  
Masato Egawa ◽  
Tadasu Matsumoto ◽  
Rina Kobayashi ◽  
...  
Keyword(s):  
Atopic Dermatitis ◽  
Disease Severity ◽  
Neurotrophic Factor ◽  
Brain Derived Neurotrophic Factor ◽  
Factor Level ◽  
Relationship Of

Serum eosinophil derived neurotoxin may reflect more strongly disease severity in childhood atopic dermatitis than eosinophil cationic protein

2001 ◽  
Vol 26 (1) ◽  
pp. 79-82 ◽  
Author(s):  
Shoichiro Taniuchi ◽  
Junichi Chihara ◽  
Takatsugu Kojima ◽  
Akemi Yamamoto ◽  
Misa Sasai ◽  
...  
Keyword(s):  
Atopic Dermatitis ◽  
Disease Severity ◽  
Eosinophil Cationic Protein ◽  
Cationic Protein

Eosinophil cationic protein in atopic dermatitis: changes of serum levels by the anti-allergic agent ketotifen *

1994 ◽  
Vol 3 (1) ◽  
pp. 59-62 ◽  
Author(s):  
Kouichi Ikai ◽  
Atsuhiko Ogino ◽  
Ikuko Furukawa ◽  
Motoaki Ozaki ◽  
Mayumi Fujita ◽  
...  
Keyword(s):  
Atopic Dermatitis ◽  
Eosinophil Cationic Protein ◽  
Serum Levels ◽  
Cationic Protein

Serum Eosinophil Cationic Protein in Patients with Atopic Dermatitis

1991 ◽  
Vol 96 (2) ◽  
pp. 175-178 ◽  
Author(s):  
R. Paganelli ◽  
E. Fanales-Belasio ◽  
D. Carmini ◽  
E. Scala ◽  
P. Meglio ◽  
...  
Keyword(s):  
Atopic Dermatitis ◽  
Eosinophil Cationic Protein ◽  
Cationic Protein

Serum eosinophil cationic protein in children with atopic dermatitis

2006 ◽  
Vol 45 (10) ◽  
pp. 1156-1160 ◽  
Author(s):  
Murat-Sušić Slobodna ◽  
Lipozenčić Jasna ◽  
Žiǎić Vesna ◽  
Husar Karmela ◽  
Marinović Branka
Keyword(s):  
Atopic Dermatitis ◽  
Eosinophil Cationic Protein ◽  
Cationic Protein

scholarly journals In vitroRelease of Eosinophil Proteins in Allergic and Atopic Dermatitis Patients

1994 ◽  
Vol 3 (3) ◽  
pp. 223-227 ◽  
Author(s):  
L. K. Poulsen ◽  
C. M. Reimert ◽  
C. Bindslev-Jensen
Keyword(s):  
Atopic Dermatitis ◽  
Eosinophil Cationic Protein ◽  
Coagulation Cascade ◽  
Clotting Time ◽  
Cationic Protein ◽  
Protein X ◽  
Inhalant Allergy ◽  
Different Levels ◽  
Increased Susceptibility

To investigate whether eosinophils are stimulatedin vivoor have acquired an increased susceptibility to stimuli from the coagulation cascade, the release of eosinophil proteins was compared for three groups of donors with different levels of serum IgE. (1) with atopic dermatitis (s-IgE > 5000 IU/ml,n= 11); (2) with inhalant allergy (200 < s-IgE < 2 000 IU/ml,n= 10); and (3) non-allergic (s- IgE < 100 IU/ml,n= 10). The levels of eosinophil cationic protein and eosinophil protein X (ECP, EPX) were determined in serum (clotting time = 2.0 h) and plasma. Serum and plasma ECP in normal donors demonstrated large intra-personal variations (C.V. 50–80%), but serum-ECP (mean 8.1 ng/ml) was clearly distinguishable from plasma ECP (mean 1.0 ng/ml) by a factor of 8 (range: 5.6–11.6). The ECP released during clotting was markedly increased in the atopic dermatitis group (serum:plasma ratio 13.5,p<0.003) compared with the other groups (6.7 and 5.6). EPX, having a higher plasma level, demonstrated a less pronounced release (serum: plasma ratios 2.0, 1.7 and 1.4), with no statistical difference between donor groups. Considering all donors together the levels of ECP and EPX in plasma and in serum were correlated to the number of eosinophils (coefficients of correlation 0.54-0.58,p<0.002).

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