Two galactose-α-1,3-galactose carrying peptidases from pork kidney mediate anaphylactogenic responses in delayed meat allergy

Allergy ◽  
2016 ◽  
Vol 71 (5) ◽  
pp. 711-719 ◽  
Author(s):  
C. Hilger ◽  
J. Fischer ◽  
K. Swiontek ◽  
F. Hentges ◽  
C. Lehners ◽  
...  
Keyword(s):  
Meat Allergy ◽  
Pork Kidney

Characterization of Major Allergens of Local Mud Crab (Scylla serrata)

2015 ◽  
Vol 12 (1) ◽  
pp. 1 ◽  
Author(s):  
Rosmilah Misnan ◽  
Nurul Izzah Abdul Rahman ◽  
Zailatul Hani Mohd Yadzir ◽  
Noormalin Abdullah ◽  
Mohd Faizal Bakhtiar ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Arginine Kinase ◽  
Mass Spectrometry Analysis ◽  
Scylla Serrata ◽  
Mud Crab ◽  
Meat Allergy ◽  
Proteomic Approach ◽  
The World ◽  
Major Allergens ◽  
Crab Meat

Crab meat is widely consumed in several countries around the world. However, when consumed, crab meats are frequent cause of allergic reactions throughout the world. Scylla serrata is among the most common mud crab in Malaysia. In a previous study two major allergens of mud crab at 36 and 41 kDa was identified. Thus, the aim of this study is to further identify these major allergens by a proteomic approach. Protein extract was prepared and resolved by 2-dimensional electrophoresis (2-DE). Immunoblotting was then performed using reactive sera from patients with crab allergy. Major allergenic spots were then excised from the 2-DE gel and analysed by mass spectrometry. The 2-DE profile of the extract revealed approximately >100 protein spots between pH of 4.00 to 8.00. Mass spectrometry analysis has identified the 36 and 41 kDa proteins as tropomyosin and arginine kinase, respectively. Our findings indicated that tropomyosin and arginine kinase play a major role in allergic reaction to mud crab meat among local patients with crab meat allergy, and should be included in diagnostics and therapeutic strategies of this allergy.

scholarly journals Could chiggers be contributing to the prevalence of galactose-alpha-1,3-galactose sensitization and mammalian meat allergy?

2019 ◽  
Vol 7 (2) ◽  
pp. 664-666 ◽  
Author(s):  
Lindsey P. Stoltz ◽  
Leslie M. Cristiano ◽  
Ashley P.G. Dowling ◽  
Jeffrey M. Wilson ◽  
Thomas A.E. Platts-Mills ◽  
...  
Keyword(s):  
Meat Allergy ◽  
Mammalian Meat

Delayed reaction in alpha‐gal allergy is reflected in serum levels after ingestion of pork kidney, and absorption is dependent on food processing

2021 ◽  
Author(s):  
Esben Eller ◽  
Per Stahl Skov ◽  
Katrine Baumann ◽  
Christiane Hilger ◽  
Markus Ollert ◽  
...  
Keyword(s):  
Food Processing ◽  
Serum Levels ◽  
Delayed Reaction ◽  
Pork Kidney

Identification of galactose-α-1,3-galactose in the gastrointestinal tract of the tickIxodes ricinus; possible relationship with red meat allergy

Allergy ◽  
2013 ◽  
Vol 68 (4) ◽  
pp. 549-552 ◽  
Author(s):  
C. Hamsten ◽  
M. Starkhammar ◽  
T. A. T. Tran ◽  
M. Johansson ◽  
U. Bengtsson ◽  
...  
Keyword(s):  
Gastrointestinal Tract ◽  
Red Meat ◽  
Meat Allergy ◽  
Red Meat Allergy
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