Allergic Skin Diseases

Allergy ◽  
2013 ◽  
Vol 68 ◽  
pp. 35-39
Keyword(s):  
Skin Diseases ◽  
Allergic Skin

scholarly journals The role of vitamin D in the immunopathogenesis of allergic skin diseases

Allergy ◽  
2011 ◽  
Vol 67 (3) ◽  
pp. 296-301 ◽  
Author(s):  
A. A. Benson ◽  
J. A. Toh ◽  
N. Vernon ◽  
S. P. Jariwala
Keyword(s):  
Vitamin D ◽  
Skin Diseases ◽  
Allergic Skin

Early clinical and laboratory diagnostics of allergodermatoses in electroplating shop workers

2021 ◽  
Vol 65 (4) ◽  
pp. 365-371
Author(s):  
Elena N. Kryuchkova ◽  
Irina V. Jatcyna ◽  
Larisa I. Antoshina
Keyword(s):  
Skin Diseases ◽  
Nickel Content ◽  
Allergic Diseases ◽  
Risk Groups ◽  
Machine Building ◽  
Control Group ◽  
Laboratory Diagnostics ◽  
Production Environment ◽  
Nickel Compounds ◽  
Allergic Skin

Introduction. At the present stage, the occupational pathology of the skin remains one of the significant medical and social problems. In this regard, special attention is paid to the early diagnosis of sensitization to industrial chemical allergens to target occupational allergic diseases. The aim of the study was to study the changes in clinical and laboratory parameters in the formation of allergic skin diseases in workers during nickel plating. Material and methods. Three hundred eighty-nine employees of the machine-building enterprise were examined. The leading group consisted of 214 people exposed to harmful chemical factors of production. Group of intact persons 175 people is represented by employees who do not come into contact with harmful factors of the production environment. The condition of the skin of workers was analyzed. Laboratory studies of oxidative metabolism and immune status were performed according to unified methods. The nickel content in the urine was determined by voltammetry. Results. At the studied enterprise, 38,3% of workers were diagnosed with occupational skin diseases (epidermosis, allergic dermatitis, eczema). In the formation of dermatological morbidity, an increase in the activity of alkaline (ALPn) and acid (ACPn) phosphatase of neutrophils by 1,7-2.2 times and inhibition of succinate dehydrogenase (SDH) and neutrophil myeloperoxidase (MPn) by 1.2-1.5 times relative to the control group was found. On the part of the immune system, there was an activation of the suppressor function of T-lymphocytes (CD8+); B-lymphocytes (CD20+), an increase in the content of immunoglobulins IgG, total IgE, circulating immune complexes by 1.5-2.0 times and a decrease in the levels of immunoglobulins IgA, IgM by 3.0-5.0 times compared to the control. The relationship between the nickel content in the urine of workers and changes in the indicators of ACPn (r = 0.76), MPn (r = -0.87), (CD4+) (r = -0.91), (CD8+) (r = 0,86), general IgE (r = 0.92), indicating the priority role of nickel compounds in the formation of allergodermatoses in workers. Conclusion. The proposed complex of biomarkers aims to detect early the initial forms of allergodermatosis and the formation of risk groups for the timely rehabilitation of electroplating workers.

The role of IL-17, IL-23 and IL-31, IL-33 in allergic skin diseases

2020 ◽  
Vol 20 (4) ◽  
pp. 367-373
Author(s):  
Fatih A. Topal ◽  
Torsten Zuberbier ◽  
Michael P. Makris ◽  
Maja Hofmann
Keyword(s):  
Skin Diseases ◽  
Allergic Skin

scholarly journals Renowned scientist, pedagogue, and physician Dedicated to the memory of the 110th anniversary of Bronius Sidaravičius’s birth

Medicina ◽  
2007 ◽  
Vol 43 (9) ◽  
pp. 679
Author(s):  
Gryta Laurynaitytė ◽  
Asta Lignugarienė ◽  
Skaidra Valiukevičienė
Keyword(s):  
Skin Diseases ◽  
Experimental Studies ◽  
Primary Sources ◽  
Venereal Diseases ◽  
Skin Allergy ◽  
Allergic Skin ◽  
Control And Prevention ◽  
History Of ◽  
State Archives ◽  
The University

This year we celebrate the 110th anniversary of Bronius Sidaravičius’s (1897–1969) birth. He was a renowned Lithuanian dermato-venereologist, professor, head of the Department of Skin and Venereal Diseases at Vytautas Magnus University (1935–1946, 1956–1969), the founder and the chair of the Lithuanian Society of Dermato-venereologists, coeditor of the prewar journal “Medicina.” He is an author of more than 100 articles and the very first course book on dermato-venereology in Lithuanian. He completed a part of his medical studies at universities in Germany. In Vienna University (1930), B. Sidaravičius performed clinical and experimental studies on the passive transmission of skin allergy, which had a major impact on the diagnostics of allergic skin diseases and specific desensibilization. He published the results of his study in the foreign literature and in the doctoral dissertation “Skin allergy and its treatment” in 1931. Thanks to the efforts of B. Sidaravičius and his colleagues, a progressive Law on Control and Prevention of Venereal Diseases was enacted in Lithuania. According to this Law, examinations and treatment of venereal diseases became compulsory and free of charge at state- or municipality-financed venereal outpatient units. This article was prepared on the basis of primary sources: protocols of the Council (the Faculty of Medicine, the University of Lithuania; since 1930 – Vytautas Magnus University) kept at the Museum of the History of Lithuania Medicine and Pharmacy as well as documents preserved at the Lithuanian State Archives and also scientific journals and periodicals both in Lithuanian and foreign languages.

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