Maternal and newborn vitamin D status and its impact on food allergy development in the German LINA cohort study

Allergy ◽  
2012 ◽  
Vol 68 (2) ◽  
pp. 220-228 ◽  
Author(s):  
K. Weisse ◽  
S. Winkler ◽  
F. Hirche ◽  
G. Herberth ◽  
D. Hinz ◽  
...  
Keyword(s):  
Vitamin D ◽  
Cohort Study ◽  
Food Allergy ◽  
Vitamin D Status ◽  
Maternal And Newborn

scholarly journals Low maternal vitamin D status and fetal bone development: Cohort study

2009 ◽  
Vol 25 (1) ◽  
pp. 14-19 ◽  
Author(s):  
Pamela Mahon ◽  
Nicholas Harvey ◽  
Sarah Crozier ◽  
Hazel Inskip ◽  
Sian Robinson ◽  
...  
Keyword(s):  
Vitamin D ◽  
Cohort Study ◽  
Bone Development ◽  
Vitamin D Status ◽  
Maternal Vitamin ◽  
Fetal Bone ◽  
Maternal Vitamin D Status

scholarly journals Vitamin D status in pregnant women and their newborns in a tertiary care hospital

2018 ◽  
Vol 7 (12) ◽  
pp. 5071
Author(s):  
Harleen Kour ◽  
Shashi Gupta ◽  
Swarn K. Gupta ◽  
Bawa Ram Bhagat ◽  
Gagan Singh
Keyword(s):  
Vitamin D ◽  
Pregnant Women ◽  
Vitamin D Deficiency ◽  
Tertiary Care ◽  
North India ◽  
Care Hospital ◽  
Vitamin D Status ◽  
Pregnant Females ◽  
Vitamin D Levels ◽  
Maternal And Newborn

Background: In the recent years there has been an increased understanding of the role that vitamin D plays in regulation of cell growth, calcium absorption and immunity and its impact on the developing fetus and maternal health is of significant concern. This study aims at evaluating the Vitamin D status in pregnant women and their newborns.Methods: A cross sectional study was done on 100 pregnant females according to inclusion and exclusion criteria. At the time of delivery, maternal blood was collected, and newborn samples were taken from newborn side of umbilical cord and sent for analysis.Results: The prevalence of Vitamin D deficiency has been found to be 85% of pregnant females and 91% of the newborns. Only 5% of pregnant females and 1% of the newborns showed Vitamin D sufficiency. Maternal and newborn vitamin D levels show a positive correlation. Mean maternal and newborn Vitamin D levels were found to be 16.78±7.04 ng/mL and 11.29±5.75 ng/ml.Conclusions: Vitamin D deficiency is highly prevalent among pregnant women in north India. Low maternal vitamin D levels lead to vitamin D deficiency in the newborns also.

scholarly journals Global summary of maternal and newborn vitamin D status - a systematic review

2015 ◽  
Vol 12 (4) ◽  
pp. 647-668 ◽  
Author(s):  
Rajneeta Saraf ◽  
Susan M.B. Morton ◽  
Carlos A. Camargo ◽  
Cameron C. Grant
Keyword(s):  
Systematic Review ◽  
Vitamin D ◽  
Vitamin D Status ◽  
Maternal And Newborn

scholarly journals Vitamin D status and the risk of type 2 diabetes: The Melbourne Collaborative Cohort Study

2019 ◽  
Vol 149 ◽  
pp. 179-187 ◽  
Author(s):  
Alicia K. Heath ◽  
Elizabeth J. Williamson ◽  
Allison M. Hodge ◽  
Peter R. Ebeling ◽  
Darryl W. Eyles ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Vitamin D ◽  
Cohort Study ◽  
Vitamin D Status ◽  
Melbourne Collaborative Cohort Study

Questioning the adequacy of standardized vitamin D supplementation protocol in very low birth weight infants: a prospective cohort study

2021 ◽  
Vol 0 (0) ◽  
Author(s):  
Hatice Sarıdemir ◽  
Ozge Surmeli Onay ◽  
Ozge Aydemir ◽  
Ayse Neslihan Tekin
Keyword(s):  
Vitamin D ◽  
Cohort Study ◽  
Birth Weight ◽  
Low Birth Weight ◽  
Prospective Cohort ◽  
Very Low Birth Weight ◽  
Vitamin D Supplementation ◽  
Vitamin D Status ◽  
Vlbw Infants ◽  
Vitamin D Levels

Abstract Objectives Preterm infants are at increased risk for vitamin D deficiency (VDD). We aimed to assess the adequacy of standardized vitamin D supplementation protocol in very low birth weight (VLBW) infants. Additionally, vitamin D status of mother/infant couples and the associations between vitamin D status at birth and morbidities of the infants were investigated. Methods In this single-center, prospective cohort study blood samples were collected from 55 mothers just before delivery and from their infants at birth and on the 30th day of life (DOL) for 25 hydroxy vitamin D (25OHD) measurements. Vitamin D was initiated in dose of 160 IU/kg by parenteral nutrition on the first DOL and oral vitamin D supplementation (400 IU/day) was administered when enteral feedings reached 50% of total intake or on the 15th DOL. Results The median 25OHD levels of the infants were 16.12 (9.14–20.50) in cord blood and 36.32 (31.10–44.44) in venous blood on the 30th DOL (p<0.01). In 98% of the VLBW infants 25OHD reached sufficient levels on the 30th DOL. None of the mothers had sufficient vitamin D levels (25OHD >30 ng/mL). Maternal 25OHD levels were correlated with the 25OHD levels of the infants in cord blood (r=0.665, p<0.001). There was a significant difference in mean cord 25OHD levels between winter (13.65 ± 5.69 ng/mL) and summer seasons (19.58 ± 11.67 ng/mL) (p=0.021). No association was found between neonatal morbidity and vitamin D status. Conclusions The results clearly show that by utilizing the current supplementation protocol, the majority of VLBW infants with deficient/insufficient serum 25OHD levels reached sufficient levels on the 30th DOL. Furthermore, vitamin D levels in mother/infant couples were found to be highly correlated.

scholarly journals Late Pregnancy Vitamin D Deficiency is Associated with Doubled Odds of Birth Asphyxia and Emergency Caesarean Section: A Prospective Cohort Study

2020 ◽  
Vol 24 (11) ◽  
pp. 1412-1418
Author(s):  
Hanna Augustin ◽  
Sinead Mulcahy ◽  
Inez Schoenmakers ◽  
Maria Bullarbo ◽  
Anna Glantz ◽  
...  
Keyword(s):  
Vitamin D ◽  
Cohort Study ◽  
Caesarean Section ◽  
Vitamin D Deficiency ◽  
Epidural Anaesthesia ◽  
Birth Asphyxia ◽  
Late Pregnancy ◽  
Population Based ◽  
Emergency Caesarean Section ◽  
Vitamin D Status

Abstract Objectives The aim of this prospective cohort study was to investigate the associations between maternal vitamin D status in late pregnancy and emergency caesarean section (EMCS) and birth asphyxia, in a population based sample of women in Sweden. Methods Pregnant women were recruited at the antenatal care in Sweden and 1832 women were included after exclusion of miscarriages, terminated pregnancies and missing data on vitamin D status. Mode of delivery was retrieved from medical records. EMCS was defined as caesarean section after onset of labour. Birth asphyxia was defined as either 5 min Apgar score < 7 or arterial umbilical cord pH < 7.1. Serum was sampled in the third trimester of pregnancy (T3) and 25-hydroxyvitamin D (25OHD) was analysed by liquid chromatography tandem mass spectrometry. Vitamin D deficiency was defined as 25OHD < 30 nmol/L, and associations were studied using logistic regression analysis and expressed as adjusted odds ratios (AOR). Results In total, 141 (7.7%) women had an EMCS and 58 (3.2%) children were born with birth asphyxia. Vitamin D deficiency was only associated with higher odds of EMCS in women without epidural anaesthesia (AOR = 2.01, p = 0.044). Vitamin D deficiency was also associated with higher odds of birth asphyxia (AOR = 2.22, p = 0.044). Conclusions for Practice In this Swedish prospective population-based cohort study, vitamin D deficiency in late pregnancy was associated with doubled odds of birth asphyxia and with EMCS in deliveries not aided by epidural anaesthesia. Prevention of vitamin D deficiency among pregnant women may reduce the incidence of EMCS and birth asphyxia. The mechanism behind the findings require further investigation.

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