scholarly journals Successful lung transplantation with graft recovered after thoracoabdominal normothermic perfusion from donor after circulatory death

2021 ◽  
Author(s):  
Marian Urban ◽  
Anthony W. Castleberry ◽  
Nicholas W. Markin ◽  
Megan M. Chacon ◽  
Heather M. Strah ◽  
...  
Keyword(s):  
Lung Transplantation ◽  
Normothermic Perfusion ◽  
Circulatory Death

Effect on the donor lungs of using abdominal normothermic regional perfusion in controlled donation after circulatory death

2020 ◽  
Author(s):  
Shin Tanaka ◽  
Jose Luis Campo-Cañaveral de la Cruz ◽  
Silvana Crowley Carrasco ◽  
Alejandra Romero Román ◽  
Lucas Hoyos Mejía ◽  
...  
Keyword(s):  
Lung Transplantation ◽  
Organ Procurement ◽  
Donation After Circulatory Death ◽  
Primary Graft Dysfunction ◽  
Abdominal Organ ◽  
Graft Dysfunction ◽  
Abdominal Organs ◽  
Normothermic Regional Perfusion ◽  
Transplantation Outcomes ◽  
Circulatory Death

Abstract OBJECTIVES Controlled donation after circulatory death (cDCD) donors are becoming a common source of organs for transplantation globally. However, the graft survival rate of cDCD abdominal organs is inferior to that of organs from brain-dead donors. The rapid retrieval (RR) technique is used by most donor organ procurement teams. The abdominal normothermic regional perfusion (A-NRP) technique has been implemented to minimize warm ischaemic damage to the abdominal organs. However, there is limited information on the effect of A-NRP on the quality of the donor lungs. This study aimed to compare lung transplantation outcomes using lungs procured from cDCD donors using the A-NRP and abdominal RR techniques. METHODS A single-centre retrospective analysis of consecutive transplant recipients of cDCD lungs from June 2013 to December 2019 was performed. The recipients were divided into 2 cohorts according to the abdominal procurement technique used. The recipient and donor characteristics (age, sex, cause of brain injury, warm ischaemic time, diagnosis, lung allocation score and other factors), incidence of primary graft dysfunction and early survival were monitored. RESULTS Twenty-eight consecutive lung transplantation recipients were identified (median age 59 years; 61% male); 14 recipients received lungs using the A-NRP and 14 using abdominal RR for abdominal organ retrieval. There were no significant differences in the baseline characteristics, primary graft dysfunction (P = 0.70), hospital mortality (P = 1.0) and 1-year survival rate (P = 1.0) between the 2 groups. CONCLUSIONS No difference was observed in lung transplantation outcomes irrespective of the abdominal organ procurement technique used (A-NRP or abdominal RR).

Donation After Circulatory Death Donors for Lung Transplantation: the US and Worldwide Status

2021 ◽  
Author(s):  
Ahmed Alnajar ◽  
Ahmed Sayed ◽  
Omar Shazly ◽  
Sophia H. Roberts ◽  
Ali Ghodsizad ◽  
...  
Keyword(s):  
Lung Transplantation ◽  
Donation After Circulatory Death ◽  
The Us ◽  
Circulatory Death

International Society for Heart and Lung Transplantation Donation After Circulatory Death Registry Report

2015 ◽  
Vol 34 (10) ◽  
pp. 1278-1282 ◽  
Author(s):  
Marcelo Cypel ◽  
Bronwyn Levvey ◽  
Dirk Van Raemdonck ◽  
Michiel Erasmus ◽  
John Dark ◽  
...  
Keyword(s):  
Lung Transplantation ◽  
International Society ◽  
Donation After Circulatory Death ◽  
Death Registry ◽  
Registry Report ◽  
Circulatory Death

Hearts transplanted after circulatory death in children: Analysis of the International Society for Heart and Lung Transplantation registry

2017 ◽  
Vol 21 (8) ◽  
pp. e13064 ◽  
Author(s):  
Jake A. Kleinmahon ◽  
Sonali S. Patel ◽  
Scott R. Auerbach ◽  
Joseph Rossano ◽  
Melanie D. Everitt
Keyword(s):  
Lung Transplantation ◽  
International Society ◽  
Circulatory Death
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