Posttransplant recurrence of calcium oxalate crystals in patients with primary hyperoxaluria: Incidence, risk factors, and effect on renal allograft function

2021 ◽  
Author(s):  
Lynn D. Cornell ◽  
Hatem Amer ◽  
Jason K. Viehman ◽  
Ramila A. Mehta ◽  
John C. Lieske ◽  
...  
Keyword(s):  
Risk Factors ◽  
Calcium Oxalate ◽  
Renal Allograft ◽  
Primary Hyperoxaluria ◽  
Calcium Oxalate Crystals ◽  
Oxalate Crystals ◽  
Allograft Function ◽  
Incidence Risk

Incidence, risk factors, and the impact of allograft pyelonephritis on renal allograft function

2016 ◽  
Vol 18 (5) ◽  
pp. 647-660 ◽  
Author(s):  
R. Singh ◽  
S.E. Geerlings ◽  
H. Peters-Sengers ◽  
M.M. Idu ◽  
C.J. Hodiamont ◽  
...  
Keyword(s):  
Risk Factors ◽  
Renal Allograft ◽  
Allograft Function ◽  
Incidence Risk ◽  
The Impact

Encapsulating Peritoneal Sclerosis in a Patient with Primary Hyperoxaluria Type 1: A Case Report

2010 ◽  
Vol 30 (1) ◽  
pp. 108-111
Author(s):  
Jill Vanmassenhove ◽  
Raymond Vanholder ◽  
Ramses Forsyth ◽  
Annemieke Dhondt
Keyword(s):  
Renal Failure ◽  
Peritoneal Dialysis ◽  
Calcium Oxalate ◽  
Primary Hyperoxaluria ◽  
Calcium Oxalate Crystals ◽  
Primary Hyperoxaluria Type 1 ◽  
Primary Hyperoxaluria Type ◽  
Oxalate Crystals ◽  
Hyperoxaluria Type

Primary hyperoxaluria type 1 (PH1) is a rare metabolic disorder caused by a defect in glyoxylate metabolism attributable to low or absent activity of the liver-specific peroxisomal enzyme alanine/glyoxylate aminotransferase. This defect leads to enhanced conversion of glyoxylate to poorly soluble oxalate, which is then excreted into the urine. This process may lead to deposition of calcium oxalate crystals in many tissues as well as in the kidneys, resulting in nephrolithiasis, nephrocalcinosis, and/or renal failure.We present a 39-year-old patient with end-stage renal failure due to PH1, who was admitted with symptoms of feeling bloated, vomiting, diarrhea, and abdominal pain related to encapsulating peritoneal sclerosis (EPS). He had been treated with peritoneal dialysis for a total period of 5 years.EPS is a rare condition characterized by fibrosis and adhesions of the peritoneum to loops of the small intestine and has been described secondary to treatment with peritoneal dialysis. It also occurs in a variety of other clinical conditions such as autoimmune diseases and peritoneal and intra-abdominal malignancies.The calcium oxalate crystals found in the peritoneal fascia of this particular patient may suggest a causative relationship between crystal deposits and evolution to fibrosis and sclerosis of the peritoneum. The degree of impact of the peritoneal dialysis treatment itself on the development of EPS, however, is uncertain.

scholarly journals Autopsy Findings in an Infant with Primary Hyperoxaluria (Type-1)

2020 ◽  
Vol 7 (12) ◽  
pp. C178-182
Author(s):  
Aman Kumar ◽  
Prateek Kinra ◽  
A W Kashif
Keyword(s):  
Calcium Oxalate ◽  
Polarized Light ◽  
Primary Hyperoxaluria ◽  
Calcium Oxalate Crystals ◽  
Primary Hyperoxaluria Type 1 ◽  
Crystal Deposition ◽  
Primary Hyperoxaluria Type ◽  
Oxalate Crystals ◽  
Hyperoxaluria Type

Histopathological findings in oxalosis patient are limited in the literature, although it has high mortality. Oxalosis, which is defined as deposition of calcium oxalate crystals in tissues, is the final stage of various hyperoxaluric syndromes. It is often missed and is rare. The diagnosis is often delayed, since it requires special laboratory tests for establishing the diagnosis. Kidneys, blood vessel walls, and bones are the major sites for crystal deposition. We present an infant autopsy case of primary hyperoxaluria, type 1. Diagnosis was established with genetic testing. On autopsy, calcium oxalate crystals which were refringent to polarized light were found in both kidneys.

An SEM study of raphide crystal initials in the leaves of vitis (grape)

1995 ◽  
Vol 53 ◽  
pp. 984-985
Author(s):  
H. J. Arnott ◽  
M. A. Webb ◽  
L. E. Lopez
Keyword(s):  
Calcium Oxalate ◽  
Water Soluble ◽  
Calcium Oxalate Crystals ◽  
Calcium Oxalate Crystal ◽  
Oxalate Crystals ◽  
Large Numbers ◽  
Sem Study ◽  
The Matrix ◽  
Crystal Cells ◽  
Crystal Idioblast

Many papers have been published on the structure of calcium oxalate crystals in plants, however, few deal with the early development of crystals. Large numbers of idioblastic calcium oxalate crystal cells are found in the leaves of Vitis mustangensis, V. labrusca and V. vulpina. A crystal idioblast, or raphide cell, will produce 150-300 needle-like calcium oxalate crystals within a central vacuole. Each raphide crystal is autonomous, having been produced in a separate membrane-defined crystal chamber; the idioblast''s crystal complement is collectively embedded in a water soluble glycoprotein matrix which fills the vacuole. The crystals are twins, each having a pointed and a bidentate end (Fig 1); when mature they are about 0.5-1.2 μn in diameter and 30-70 μm in length. Crystal bundles, i.e., crystals and their matrix, can be isolated from leaves using 100% ETOH. If the bundles are treated with H2O the matrix surrounding the crystals rapidly disperses.

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