scholarly journals Donor genetic variants as risk factors for thrombosis after liver transplantation: A genome‐wide association study

2021 ◽  
Author(s):  
Yanni Li ◽  
Lianne M. Nieuwenhuis ◽  
Michiel D. Voskuil ◽  
Ranko Gacesa ◽  
Shixian Hu ◽  
...  
Keyword(s):  
Risk Factors ◽  
Liver Transplantation ◽  
Association Study ◽  
Genetic Variants ◽  
Genome Wide Association Study ◽  
Genome Wide Association ◽  
Genome Wide ◽  
A Genome

scholarly journals Genetic risk factors for variant Creutzfeldt–Jakob disease: a genome-wide association study

2009 ◽  
Vol 8 (1) ◽  
pp. 57-66 ◽  
Author(s):  
Simon Mead ◽  
Mark Poulter ◽  
James Uphill ◽  
John Beck ◽  
Jerome Whitfield ◽  
...  
Keyword(s):  
Risk Factors ◽  
Association Study ◽  
Genetic Risk ◽  
Genome Wide Association Study ◽  
Genetic Risk Factors ◽  
Genome Wide Association ◽  
Genome Wide ◽  
A Genome ◽  
Jakob Disease

scholarly journals Identification of genetic variants associated with Huntington's disease progression: a genome-wide association study

2017 ◽  
Vol 16 (9) ◽  
pp. 701-711 ◽  
Author(s):  
Davina J Hensman Moss ◽  
Antonio F Pardiñas ◽  
Douglas Langbehn ◽  
Kitty Lo ◽  
Blair R Leavitt ◽  
...  
Keyword(s):  
Huntington's Disease ◽  
Association Study ◽  
Huntington’S Disease ◽  
Disease Progression ◽  
Genetic Variants ◽  
Genome Wide Association Study ◽  
Genome Wide Association ◽  
Genome Wide ◽  
A Genome

scholarly journals A genome-wide association study of total child psychiatric problems scores

2020 ◽  
Author(s):  
Alexander Neumann ◽  
Ilja M. Nolte ◽  
Irene Pappa ◽  
Tarunveer S. Ahluwalia ◽  
Erik Pettersson ◽  
...  
Keyword(s):  
Association Study ◽  
Psychiatric Disorders ◽  
Genetic Variants ◽  
Genome Wide Association Study ◽  
Genome Wide Association ◽  
Psychiatric Problem ◽  
Problem Score ◽  
Genome Wide ◽  
A Genome ◽  
Psychiatric Problems

ABSTRACTSubstantial genetic correlations have been reported across psychiatric disorders and numerous cross-disorder genetic variants have been detected. To identify the genetic variants underlying general psychopathology in childhood, we performed a genome-wide association study using a total psychiatric problem score. We analyzed 6,844,199 common SNPs in 38,418 school-aged children from 20 population-based cohorts participating in the EArly Genetics and Lifecourse Epidemiology (EAGLE) consortium. The SNP heritability of total psychiatric problems was 5.4% (SE=0.01) and two loci reached genome-wide significance: rs10767094 and rs202005905. We also observed an association of SBF2, a gene associated with neuroticism in previous GWAS, with total psychiatric problems. The genetic effects underlying the total psychiatric problem score were shared with known genetic variants for common psychiatric disorders only (attention-deficit/hyperactivity disorder, anxiety, depression, insomnia) (rG > 0.49), but not with autism or the less common adult disorders (schizophrenia, bipolar disorder, or eating disorders) (rG < 0.01). Importantly, the total psychiatric problem score also showed at least a moderate genetic correlation of with intelligence, educational attainment, wellbeing, smoking, and body fat (rG > 0.29).The results suggest that many common genetic variants are associated with childhood psychiatric symptoms and related phenotypes in general instead of with specific symptoms. Further research is needed to establish causality and pleiotropic mechanisms between psychiatric disorders and related traits.

Detection of genetic variants affecting cattle behaviour and their impact on milk production: a genome-wide association study

2015 ◽  
Vol 47 (1) ◽  
pp. 12-18 ◽  
Author(s):  
Juliane Friedrich ◽  
Bodo Brand ◽  
Siriluck Ponsuksili ◽  
Katharina L. Graunke ◽  
Jan Langbein ◽  
...  
Keyword(s):  
Association Study ◽  
Milk Production ◽  
Genetic Variants ◽  
Genome Wide Association Study ◽  
Genome Wide Association ◽  
Genome Wide ◽  
A Genome
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