scholarly journals Use of expanded‐criteria donors and > 85 KDPI kidneys for pediatric kidney transplantation in the United States

2020 ◽  
Author(s):  
Sarah J. Kizilbash ◽  
Michael D. Evans ◽  
Srinath Chinnakotla ◽  
Blanche M. Chavers
Keyword(s):  
United States ◽  
Kidney Transplantation ◽  
The United States ◽  
Pediatric Kidney Transplantation ◽  
Expanded Criteria ◽  
Expanded Criteria Donors

scholarly journals Effects of COVID19 Pandemic on Pediatric Kidney Transplant in the United States

2020 ◽  
Author(s):  
Olga Charnaya ◽  
Teresa Po-Yu Chiang ◽  
Richard Wang ◽  
Jennifer Motter ◽  
Brian Boyarsky ◽  
...  
Keyword(s):  
United States ◽  
Kidney Transplantation ◽  
Disease Transmission ◽  
National Level ◽  
Rapid Change ◽  
Deceased Donor ◽  
The United States ◽  
Transplant Recipients ◽  
Pediatric Kidney Transplantation ◽  
Sustained Effect

Abstract In March 2020, COVID-19 infections began to rise exponentially in the United States, placing substantial burden on the healthcare system. As a result, there was a rapid change in transplant practices and policies, with cessation of most procedures. Our goal was to understand changes to pediatric kidney transplantation (KT) at the national level during the COVID-19 epidemic. Using SRTR data, we examined changes in pediatric waitlist registration, waitlist removal or inactivation, and deceased donor and living donor (DDKT/LDKT) events during the start of the disease transmission in the United States compared to the same time the previous year. We saw an initial decrease in DDKT and LDKT by 47% and 82% compared to expected events and then a continual increase, with numbers reaching expected pre-pandemic levels by May 2020. In the early phase of the pandemic, waitlist inactivation and removals due to death or deteriorating condition rose above expected values by 152% and 189%, respectively. There was a statistically significant decrease in new waitlist additions (IRR 0.49 0.65 0.85) and LDKT (IRR 0.17 0.38 0.84) in states with high vs low COVID activity. Transplant recipients during the pandemic were more likely to have received a DDKT, but had similar cPRA, waitlist time and cause of ESRD as before the pandemic. The COVID-19 pandemic initially reduced access to kidney transplantation among pediatric patients in the United States, but has not had a sustained effect.

Safety and Efficacy of Induction Treatment with Low Thymoglobulin Doses in Kidney Transplantation from Expanded-Criteria Donors

2015 ◽  
Vol 47 (1) ◽  
pp. 50-53 ◽  
Author(s):  
A. Sancho Calabuig ◽  
E. Gavela Martínez ◽  
J. Kanter Berga ◽  
S. Beltrán Calatán ◽  
A.I. Avila Bernabeu ◽  
...  
Keyword(s):  
Kidney Transplantation ◽  
Induction Treatment ◽  
Safety And Efficacy ◽  
Expanded Criteria ◽  
Expanded Criteria Donors
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