scholarly journals Psychological contributors to the frail phenotype: The association between resilience and frailty in patients with cirrhosis

2020 ◽  
Vol 21 (1) ◽  
pp. 241-246 ◽  
Author(s):  
Randi J. Wong ◽  
Yara Mohamad ◽  
Yanin T. Srisengfa ◽  
Dorothea S. Kent ◽  
Srilakshmi Seetharaman ◽  
...  
Keyword(s):  
Frail Phenotype

scholarly journals The frailty syndrome in older adults with type 2 diabetes mellitus and associated factors

2020 ◽  
Vol 23 (1) ◽  
Author(s):  
Bartolomeu Fagundes de Lima Filho ◽  
Antônia Gilvanete Duarte Gama ◽  
Vanessa da Nóbrega Dias ◽  
Eliza Mikaele Tavares da Silva ◽  
Fabricia Azevedo da Costa Cavalcanti ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Older Adults ◽  
Type 2 Diabetes Mellitus ◽  
Logistic Regression ◽  
Logistic Regression Model ◽  
Lower Limbs ◽  
Frailty Syndrome ◽  
Frail Phenotype

Abstract Objective: To compare clinical-functional factors among groups in relation to the frailty syndrome (pre-frail and frail) phenotype profile in older adults with type 2 diabetes mellitus (DM 2). Methods: A descriptive, analytical, cross-sectional study with a quantitative approach was performed. A total of 113 diabetic older adults of both sexes were evaluated in terms of their personal, socio-demographic, clinical-functional, mental, cognitive and fragility phenotype data. The Chi-square test and a logistic regression model were used. Results: The mean age was 68.66±6.62 years, and the sample was mostly female (61.9%), illiterate or with an incomplete primary education (60.2%), pre-frail (52.2%), sedentary (79.6%), and had been diagnosed with DM2 for more than 5 years (58.3%). There was a significant association between “pre-frail and frail” individuals and schooling (p=0.004), social participation (p=0.004), a subjective perception of vision (p=0.004), glycated hemoglobin (p=0.036), limb pain (p=0.012), depressive symptoms (p=0.002) and mobility (p=0.004). The logistic regression model showed an accuracy of 93.6% and the significant variables were education (p=0.039), pain in the lower limbs (p=0.025) and risk of falls (p=0.033). Conclusion: among all the factors related to the “pre-frail” and “frail” phenotype, schooling, pain in the lower limbs and mobility were most related to the worsening of the syndrome and its progress.

scholarly journals Association of Cardiac Abnormalities to the Frail Phenotype in Cirrhotic Patients on the Waitlist

2017 ◽  
pp. 1 ◽  
Author(s):  
Lorena Puchades ◽  
Stephanie Chau ◽  
John A. Dodson ◽  
Yara Mohamad ◽  
Rachel Mustain ◽  
...  
Keyword(s):  
Cardiac Abnormalities ◽  
Cirrhotic Patients ◽  
Frail Phenotype

scholarly journals Frail and pre-frail phenotype is associated with pain in older HIV-infected patients

Medicine ◽  
2018 ◽  
Vol 97 (6) ◽  
pp. e9852 ◽  
Author(s):  
Nathalie Petit ◽  
Patricia Enel ◽  
Isabelle Ravaux ◽  
Albert Darque ◽  
Karine Baumstarck ◽  
...  
Keyword(s):  
Frail Phenotype

scholarly journals The Depressed Frail Phenotype: The Clinical Manifestation of Increased Biological Aging

2016 ◽  
Vol 24 (11) ◽  
pp. 1084-1094 ◽  
Author(s):  
Patrick J. Brown ◽  
Bret R. Rutherford ◽  
Kristine Yaffe ◽  
Jane M. Tandler ◽  
Justina Laurence Ray ◽  
...  
Keyword(s):  
Clinical Manifestation ◽  
Biological Aging ◽  
Frail Phenotype

scholarly journals Role of Cachexia and Fragility in the Patient Candidate for Cardiac Surgery

Nutrients ◽  
2021 ◽  
Vol 13 (2) ◽  
pp. 517
Author(s):  
Calogera Pisano ◽  
Daniele Polisano ◽  
Carmela Rita Balistreri ◽  
Claudia Altieri ◽  
Paolo Nardi ◽  
...  
Keyword(s):  
Cardiac Surgery ◽  
Cardiovascular Diseases ◽  
Physical Inactivity ◽  
Relevant Literature ◽  
Accelerated Aging ◽  
Moderate Intensity ◽  
Physical Frailty ◽  
Biological Substrate ◽  
Frail Phenotype

Frailty is the major expression of accelerated aging and describes a decreased resistance to stressors, and consequently an increased vulnerability to additional diseases in elderly people. The vascular aging related to frail phenotype reflects the high susceptibility for cardiovascular diseases and negative postoperative outcomes after cardiac surgery. Sarcopenia can be considered a biological substrate of physical frailty. Malnutrition and physical inactivity play a key role in the pathogenesis of sarcopenia. We searched on Medline (PubMed) and Scopus for relevant literature published over the last 10 years and analyzed the strong correlation between frailty, sarcopenia and cardiovascular diseases in elderly patient. In our opinion, a right food intake and moderate intensity resistance exercise are mandatory in order to better prepare patients undergoing cardiac operation.

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