scholarly journals Development and validation of an optimized integrative model using urinary chemokines for noninvasive diagnosis of acute allograft rejection

2020 ◽  
Vol 20 (12) ◽  
pp. 3462-3476 ◽  
Author(s):  
Claire Tinel ◽  
Arnaud Devresse ◽  
Agathe Vermorel ◽  
Virginia Sauvaget ◽  
David Marx ◽  
...  
2014 ◽  
Vol 2014 ◽  
pp. 1-7 ◽  
Author(s):  
Helga Pawelski ◽  
Uta Schnöckel ◽  
Dominik Kentrup ◽  
Alexander Grabner ◽  
Michael Schäfers ◽  
...  

Molecular imaging techniques such as single photon emission computed tomography (SPECT) or positron emission tomography are promising tools for noninvasive diagnosis of acute allograft rejection (AR). Given the importance of renal transplantation and the limitation of available donors, detailed analysis of factors that affect transplant survival is important. Episodes of acute allograft rejection are a negative prognostic factor for long-term graft survival. Invasive core needle biopsies are still the “goldstandard” in rejection diagnostics. Nevertheless, they are cumbersome to the patient and carry the risk of significant graft injury. Notably, they cannot be performed on patients taking anticoagulant drugs. Therefore, a noninvasive tool assessing the whole organ for specific and fast detection of acute allograft rejection is desirable. We herein review SPECT- and PET-based approaches for noninvasive molecular imaging-based diagnostics of acute transplant rejection.


1998 ◽  
Vol 4 (3) ◽  
pp. 197-203 ◽  
Author(s):  
Ashokkumar Jain ◽  
Anthony J. Demetris ◽  
Rafael Manez ◽  
Athanassisos C. Tsamanadas ◽  
David Van Thiel ◽  
...  

2014 ◽  
Vol 37 (11) ◽  
pp. 803-808 ◽  
Author(s):  
Fabrizio Fabrizi ◽  
Roberta D'Ambrosio ◽  
Francesco Pallotti ◽  
Luisa Berardinelli ◽  
Piergiorgio Messa ◽  
...  

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