scholarly journals Blood pressure control according to clinical practice guidelines is associated with decreased mortality and cardiovascular events among liver transplant recipients

2019 ◽  
Vol 20 (3) ◽  
pp. 797-807 ◽  
Author(s):  
Lisa B. VanWagner ◽  
Jane L. Holl ◽  
Samantha Montag ◽  
Dyanna Gregory ◽  
Sean Connolly ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Clinical Practice ◽  
Liver Transplant ◽  
Blood Pressure Control ◽  
Clinical Practice Guidelines ◽  
Practice Guidelines ◽  
Cardiovascular Events ◽  
Pressure Control ◽  
Transplant Recipients ◽  
Liver Transplant Recipients

scholarly journals Evening anti-hypertensive dosing improves blood pressure control and reduce cardiovascular events in hypertensive: a meta-analysis of 40 trials in 44,167 patients

2020 ◽  
Vol 41 (Supplement_2) ◽  
Author(s):  
A.P Sunjaya ◽  
A.F Sunjaya
Keyword(s):  
Blood Pressure ◽  
Randomized Controlled Trials ◽  
Diastolic Blood Pressure ◽  
Blood Pressure Control ◽  
Cardiovascular Events ◽  
Meta Analysis ◽  
Pressure Control ◽  
Controlled Trials ◽  
Night Time ◽  
Randomized Controlled

Abstract Introduction Nocturnal blood pressure (BP) and early morning BP surge have consistently been found to be a better prognostic marker of cardiovascular outcome than daytime BP. Most anti-hypertensive show greater blood pressure-lowering effect in the first 12 hours compared to the next 12 hours. Several prospective studies have shown better BP regulation and improved cardiovascular risk when anti-hypertensive are ingested at bedtime versus at awakening. Purpose In patients with hypertension does evening dosing of anti-hypertensive compared to morning dosing led to better reduction in pressure, blood pressure control and reduced cardiovascular morbidity. Methods A meta-analysis was performed based on randomized controlled trials obtained from Cochrane Central Register of Controlled Trials (CENTRAL), EMBASE, Medline and Medline ahead of print published between 2000 and 2020. Main outcome measures include mean 24 hour systolic and diastolic blood pressure, cardiovascular events as well as prevalence of blood pressure in control. Data synthesis and analysis was done using RevMan 5.3 using a random effects model. Results A total of 40 randomized controlled trials, representing 44,167 patients were included in this meta-analysis. Most studies evaluate the administration of mixed anti-hypertensive with ≥1 medication ingested at bedtime, calcium channel blockers (CCBs) or angiotensin receptor blockers (ARBs) with sample sizes ranging from 30 to 19,084 patients. Evening administration of anti-hypertensive was found to significantly lower 24-hour systolic blood pressure (Mean difference = −1.05, 95% CI: −2.01 to −0.10, p=0.03) and 24-hour diastolic blood pressure (Mean difference = −1.09, 95% CI: −1.68 to −0.50, p=0.0003). Prevalence of controlled blood pressure was found to significantly increase with evening dosing (RR=1.15, 95% CI: 1.03 to 1.28, p=0.01). Significant reduction in cardiovascular events were found in the evening dosing group (RR=0.48, 95% CI: 0.03 to 0.68, p=<0.00001). Discussion Reduction in night-time blood pressure especially among non-dippers as reported in previous studies and higher prevalence of controlled blood pressure may explain the greater than 50% reduction in cardiovascular events in the evening dosing group. This marked benefit from a simple and inexpensive strategy certainly has great potential to benefit patients in practice. Even so, few studies have reported the prevalence of blood pressure in control (9 studies) and cardiovascular events (6 studies). Few has also studied this in geriatric populations where night-time hypotension and hypoperfusion may bring the most impact. Conclusion For patients with hypertension, evening dosing significantly improves blood pressure control and reduces the risk for cardiovascular events. Careful selection of anti-hypertensive administration time in patients is recommended given the possible benefits. Anti Hypertensive Dosing Forest Plot Funding Acknowledgement Type of funding source: None

Blood pressure control and risk of stroke in untreated and treated hypertensive patients screened from clinical practice: results of the ForLife study

2005 ◽  
Vol 23 (8) ◽  
pp. 1575-1581 ◽  
Author(s):  
Giuseppe Mancia ◽  
Ettore Ambrosioni ◽  
Enrico Agabiti Rosei ◽  
Gastone Leonetti ◽  
Bruno Trimarco ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Clinical Practice ◽  
Blood Pressure Control ◽  
Pressure Control ◽  
Hypertensive Patients

scholarly journals Metabolic syndrome in liver transplant recipients: Prevalence, risk factors, and association with cardiovascular events

2011 ◽  
Vol 17 (1) ◽  
pp. 15-22 ◽  
Author(s):  
Ido Laish ◽  
Marius Braun ◽  
Eytan Mor ◽  
Jaqueline Sulkes ◽  
Yael Harif ◽  
...  
Keyword(s):  
Risk Factors ◽  
Metabolic Syndrome ◽  
Liver Transplant ◽  
Cardiovascular Events ◽  
Transplant Recipients ◽  
Liver Transplant Recipients

scholarly journals Renal function improvement in liver transplant recipients after early everolimus conversion: A clinical practice cohort study in Spain

2015 ◽  
Vol 21 (8) ◽  
pp. 1056-1065 ◽  
Author(s):  
Itxarone Bilbao ◽  
Magdalena Salcedo ◽  
Miguel Angel Gómez ◽  
Carlos Jimenez ◽  
Javier Castroagudín ◽  
...  
Keyword(s):  
Renal Function ◽  
Cohort Study ◽  
Clinical Practice ◽  
Liver Transplant ◽  
Transplant Recipients ◽  
Liver Transplant Recipients
Sign in / Sign up

Export Citation Format

Share Document