scholarly journals RNA interference therapeutics in organ transplantation: The dawn of a new era

2019 ◽  
Vol 20 (4) ◽  
pp. 931-941 ◽  
Author(s):  
Isabel M. A. Brüggenwirth ◽  
Paulo N. Martins
The Lancet ◽  
2014 ◽  
Vol 384 (9945) ◽  
pp. 741 ◽  
Author(s):  
Xian Wei ◽  
Hua Jiang ◽  
Qingfeng Li

2016 ◽  
Vol 129 (16) ◽  
pp. 1891-1893 ◽  
Author(s):  
Jie-Fu Huang ◽  
Hai-Bo Wang ◽  
Shu-Sen Zheng ◽  
Yong-Feng Liu ◽  
Bing-Yi Shi ◽  
...  

The Lancet ◽  
2014 ◽  
Vol 384 (9945) ◽  
pp. 741-742 ◽  
Author(s):  
Qiquan Sun ◽  
Xinpu Gao ◽  
Dicken Shiu-Chung Ko ◽  
Xian Chang Li

Author(s):  
Ximo García-Domínguez ◽  
Cesar D. Vera-Donoso ◽  
Luís García-Valero ◽  
Jose S. Vicente ◽  
Francisco Marco-Jimenez

The Lancet ◽  
2014 ◽  
Vol 384 (9945) ◽  
pp. 741 ◽  
Author(s):  
Francis L Delmonico ◽  
Alexander M Capron ◽  
Gabriel M Danovitch ◽  
Adeera Levin ◽  
Philip J O’Connell

2021 ◽  
Vol 72 (1) ◽  
pp. 107-118
Author(s):  
Puja H. Nambiar ◽  
Brianna Doby ◽  
Aaron A.R. Tobian ◽  
Dorry L. Segev ◽  
Christine M. Durand

Implementation of the HIV Organ Policy Equity (HOPE) Act marks a new era in transplantation, allowing organ transplantation from HIV+ donors to HIV+ recipients (HIV D+/R+ transplantation). In this review, we discuss major milestones in HIV and transplantation which paved the way for this landmark policy change, including excellent outcomes in HIV D–/R+ recipient transplantation and success in the South African experience of HIV D+/R+ deceased donor kidney transplantation. Under the HOPE Act, from March 2016 to December 2018, there were 56 deceased donors, and 102 organs were transplanted (71 kidneys and 31 livers). In 2019, the first HIV D+/R+ living donor kidney transplants occurred. Reaching the full estimated potential of HIV+ donors will require overcoming challenges at the community, organ procurement organization, and transplant center levels. Multiple clinical trials are ongoing, which will provide clinical and scientific data to further extend the frontiers of knowledge in this field.


The Lancet ◽  
2014 ◽  
Vol 383 (9933) ◽  
pp. 1971-1972 ◽  
Author(s):  
Qiquan Sun ◽  
Xinpu Gao ◽  
Haibo Wang ◽  
Dicken Shiu-Chung Ko ◽  
Xian Chang Li

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