scholarly journals The Lethal and Enduring Inequity of Deceased Donor Liver Allocation Policy for Hepatocellular Carcinoma in the United States

2013 ◽  
Vol 13 (11) ◽  
pp. 2794-2796 ◽  
Author(s):  
M. Charlton
Keyword(s):  
United States ◽  
Hepatocellular Carcinoma ◽  
Deceased Donor ◽  
The United States ◽  
Donor Liver ◽  
Allocation Policy ◽  
Liver Allocation

scholarly journals Evolution of Liver Transplant Selection Criteria and U.S. Allocation Policy for Patients with Hepatocellular Carcinoma

2020 ◽  
Vol 40 (04) ◽  
pp. 358-364
Author(s):  
Julie K. Heimbach
Keyword(s):  
Hepatocellular Carcinoma ◽  
Selection Criteria ◽  
Early Stage ◽  
Treatment Strategies ◽  
Deceased Donor ◽  
The United States ◽  
Underlying Liver Disease ◽  
Recurrent Cancer ◽  
Allocation Policy ◽  
Liver Allocation

AbstractLiver transplantation (LT) is an optimal treatment option for early-stage unresectable hepatocellular carcinoma (HCC) in patients with cirrhosis as it provides a treatment for underlying liver disease as well as a decreased incidence of recurrent cancer compared with alternative treatment strategies. A primary barrier to LT for HCC is the critical shortage of available liver allografts. The system of prioritization and access to deceased donor transplantation for patient with HCC in the United States has continued to evolve, while variable approaches including no additional priority, are in use around the world. While the Milan criteria remain the most well-established pretransplantation selection criteria, multiple other algorithms which expand beyond Milan have been proposed. The current review focuses on liver allocation for HCC as well as the principles and varied models available for pretransplant patient selection.

A Critique of UNOS Liver Allocation Policy

1999 ◽  
Vol 8 (3) ◽  
pp. 311-320 ◽  
Author(s):  
KENNETH EINAR HIMMA
Keyword(s):  
United States ◽  
Liver Disease ◽  
Liver Failure ◽  
Chronic Liver Disease ◽  
The United States ◽  
Acute Illness ◽  
Waiting List ◽  
Allocation Policy ◽  
Liver Allocation ◽  
United Network

The United Network for Organ Sharing (UNOS) recently changed the policy by which donor livers are allocated to liver failure patients in the United States. Formerly, all liver failure patients were characterized as status 1 and placed at the top of the transplant list. Under the new policy, only patients with liver failure due to acute illness (“ALF patients”) are eligible for status 1; patients with liver failure due to chronic liver disease (“CLF patients”) are characterized as status 2. Since donor organs are allocated first to status 1 patients and then to status 2 patients, the new policy moves all CLF patients down on the waiting list relative to all ALF patients. This means that some livers that would have gone to CLF patients under the old policy will now go to ALF patients. Accordingly, while the new policy will likely increase the number of ALF patients saved, it will also increase the number of deaths among CLF patients waiting for a transplant.

scholarly journals New National Allocation Policy for Deceased Donor Kidneys in the United States and Possible Effect on Patient Outcomes

2014 ◽  
Vol 25 (8) ◽  
pp. 1842-1848 ◽  
Author(s):  
Ajay K. Israni ◽  
Nicholas Salkowski ◽  
Sally Gustafson ◽  
Jon J. Snyder ◽  
John J. Friedewald ◽  
...  
Keyword(s):  
United States ◽  
Patient Outcomes ◽  
Deceased Donor ◽  
The United States ◽  
Allocation Policy

scholarly journals Factors that affect deceased donor liver transplantation rates in the United States in addition to the model for end‐stage liver disease score

2012 ◽  
Vol 18 (12) ◽  
pp. 1456-1463 ◽  
Author(s):  
Pratima Sharma ◽  
Douglas E. Schaubel ◽  
Emily E. Messersmith ◽  
Mary K. Guidinger ◽  
Robert M. Merion
Keyword(s):  
United States ◽  
Liver Transplantation ◽  
Liver Disease ◽  
Deceased Donor ◽  
The United States ◽  
Disease Score ◽  
Donor Liver ◽  
Donor Liver Transplantation ◽  
End Stage Liver Disease ◽  
End Stage

ABO-incompatible deceased donor liver transplantation in the United States: A national registry analysis

2009 ◽  
Vol 15 (8) ◽  
pp. 883-893 ◽  
Author(s):  
Zoe A. Stewart ◽  
Jayme E. Locke ◽  
Robert A. Montgomery ◽  
Andrew L. Singer ◽  
Andrew M. Cameron ◽  
...  
Keyword(s):  
United States ◽  
Liver Transplantation ◽  
Deceased Donor ◽  
The United States ◽  
National Registry ◽  
Donor Liver ◽  
Donor Liver Transplantation ◽  
Deceased Donor Liver Transplantation ◽  
Registry Analysis

scholarly journals Report of a national conference on liver allocation in patients with hepatocellular carcinoma in the United States

2009 ◽  
Vol 16 (3) ◽  
pp. 262-278 ◽  
Author(s):  
Elizabeth A. Pomfret ◽  
Kenneth Washburn ◽  
Christoph Wald ◽  
Michael A. Nalesnik ◽  
David Douglas ◽  
...  
Keyword(s):  
United States ◽  
Hepatocellular Carcinoma ◽  
The United States ◽  
National Conference ◽  
Liver Allocation
Sign in / Sign up

Export Citation Format

Share Document