scholarly journals Noninvasive prenatal testing in routine clinical practice - An audit of NIPT and combined first-trimester screening in an unselected Australian population

2016 ◽  
Vol 56 (1) ◽  
pp. 22-28 ◽  
Author(s):  
Andrew McLennan ◽  
Ricardo Palma-Dias ◽  
Fabricio da Silva Costa ◽  
Simon Meagher ◽  
Debbie L. Nisbet ◽  
...  
Keyword(s):  
Clinical Practice ◽  
Prenatal Testing ◽  
First Trimester ◽  
Routine Clinical Practice ◽  
First Trimester Screening ◽  
Australian Population ◽  
Noninvasive Prenatal Testing ◽  
Trimester Screening

scholarly journals Multi-centre first-trimester screening for Down syndrome in the Netherlands in routine clinical practice

2006 ◽  
Vol 26 (8) ◽  
pp. 711-718 ◽  
Author(s):  
P. C. J. I. Schielen ◽  
M. van Leeuwen-Spruijt ◽  
I. Belmouden ◽  
L. H. Elvers ◽  
M. Jonker ◽  
...  
Keyword(s):  
Down Syndrome ◽  
Clinical Practice ◽  
The Netherlands ◽  
First Trimester ◽  
Routine Clinical Practice ◽  
First Trimester Screening ◽  
Trimester Screening

Noninvasive Prenatal Testing Decreased Diagnostic Testing but Not First-Trimester Screening

2014 ◽  
Vol 123 ◽  
pp. 88S
Author(s):  
Sebastian Larion ◽  
Malgorzata Mlynarczyk ◽  
Letty Romary ◽  
Alfred Z. Abuhamad ◽  
Steven L. Warsof
Keyword(s):  
Diagnostic Testing ◽  
Prenatal Testing ◽  
First Trimester ◽  
First Trimester Screening ◽  
Noninvasive Prenatal Testing ◽  
Trimester Screening

P03.01: First trimester screening in routine clinical practice in 5189 pregnancies

2005 ◽  
Vol 26 (4) ◽  
pp. 387-388
Author(s):  
A. Kossakiewicz ◽  
M. Kossakiewicz ◽  
S. v. d. Haar ◽  
M. Schälike ◽  
S. Neubauer
Keyword(s):  
Clinical Practice ◽  
First Trimester ◽  
Routine Clinical Practice ◽  
First Trimester Screening ◽  
Trimester Screening

Use of endocervical trophoblasts in noninvasive prenatal testing for common aneuploidies

2020 ◽  
Vol 19 (4) ◽  
pp. 75-80
Author(s):  
E.V. Musatova ◽  
◽  
M.V. Kapustina ◽  
M.E. Minzhenkova ◽  
Zh.G. Markova ◽  
...  
Keyword(s):  
Pregnant Women ◽  
Prenatal Testing ◽  
First Trimester ◽  
Dna Probes ◽  
Fish Analysis ◽  
Trophoblast Cells ◽  
Noninvasive Prenatal Testing ◽  
Chorionic Villi ◽  
Trimester Screening ◽  
Reliable Methods

The article presents an experience of isolation of trophoblast cells from cervical samples of pregnant women and demonstrates a possibility of determining aneuploid cells in cervical samples using FISH analysis. Objective. To study methods of effective isolation and reliable detection of trophoblasts for genetic pathology analysis. Patients and methods. The participants of the study were three pregnant women, who according to the findings of the combined first trimester screening test were referred to the group with a high risk for fetal aneuploidy. The terms of gestation varied from 12 to 14 wks. Immunocytochemical detection of trophoblast cells was performed with FITC-labelled HLA-G antibodies. FISH was performed with the use of locus-specific DNA probes on chromosomes 13/21 and a DNA probe on chromosome 18 centromere. The chromosome set of a fetus was verified by the results of standard cytogenetic analysis of semi-direct chromosome preparations from cytotrophoblast cells obtained by chorionic villi biopsy. Results. HLA-G-positive cells were found in all examined cytological specimens. FISH analysis with the use of DNA probes on chronomomes, whose trisomies are compatible with live birth, detected aneuploid cells in all three cases. Conclusion. The use of cervical trophoblasts for noninvasive collection of information about the genetic status of the developing fetus at present needs further study of effective and reliable methods of their isolation, detection and analysis. Key words: aneuploidy, throphoblast cells, NIPT, prenatal diagnosis, HLA-G

The impact of non-invasive prenatal testing on anxiety in women considered at high or low risk for aneuploidy after combined first trimester screening

2017 ◽  
Vol 37 (10) ◽  
pp. 975-982 ◽  
Author(s):  
Zara Richmond ◽  
Ron Fleischer ◽  
Maya Chopra ◽  
Jason Pinner ◽  
Mario D'Souza ◽  
...  
Keyword(s):  
Prenatal Testing ◽  
First Trimester ◽  
Low Risk ◽  
First Trimester Screening ◽  
Non Invasive ◽  
Trimester Screening ◽  
The Impact
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