Environmental Pollutant Polybrominated Diphenyl Ether, a Flame Retardant, Induces Primary Amnion Cell Senescence

2015 ◽  
Vol 74 (5) ◽  
pp. 398-406 ◽  
Author(s):  
Faranak Behnia ◽  
Morgan R. Peltier ◽  
George R. Saade ◽  
Ramkumar Menon
Keyword(s):  
Flame Retardant ◽  
Diphenyl Ether ◽  
Polybrominated Diphenyl Ether ◽  
Environmental Pollutant ◽  
Cell Senescence ◽  
Amnion Cell

Wastewater dilution index partially explains observed polybrominated diphenyl ether flame retardant concentrations in osprey eggs from Columbia River Basin, 2008–2009

Ecotoxicology ◽  
2011 ◽  
Vol 20 (4) ◽  
pp. 682-697 ◽  
Author(s):  
Charles J. Henny ◽  
Robert A. Grove ◽  
James L. Kaiser ◽  
Branden L. Johnson ◽  
Chad V. Furl ◽  
...  
Keyword(s):  
Flame Retardant ◽  
River Basin ◽  
Diphenyl Ether ◽  
Columbia River ◽  
Polybrominated Diphenyl Ether ◽  
Columbia River Basin

251: Polybromated diphenyl ether induces primary amnion cell senescence through p38MAPK activation

2015 ◽  
Vol 212 (1) ◽  
pp. S138-S139 ◽  
Author(s):  
Fara Behnia ◽  
George Saade ◽  
Morgan Peltier ◽  
Eryn Dutta ◽  
Talar Kechichian ◽  
...  
Keyword(s):  
Diphenyl Ether ◽  
Cell Senescence ◽  
Amnion Cell

scholarly journals A global database of polybrominated diphenyl ether flame retardant congeners in foods and supplements

2018 ◽  
Vol 69 ◽  
pp. 171-188 ◽  
Author(s):  
Beatrice A. Boucher ◽  
Julie K. Ennis ◽  
Dina Tsirlin ◽  
Shelley A. Harris
Keyword(s):  
Flame Retardant ◽  
Diphenyl Ether ◽  
Polybrominated Diphenyl Ether ◽  
Global Database

scholarly journals Effects of Decabrominated Diphenyl Ether Exposure on Growth, Meat Characteristics and Blood Profiles in Broilers

Animals ◽  
2021 ◽  
Vol 11 (2) ◽  
pp. 565
Author(s):  
Zehui Liu ◽  
Hulong Lei ◽  
Renyong Tang ◽  
Junhua Yang ◽  
Xiulan Guo ◽  
...  
Keyword(s):  
Antioxidant Capacity ◽  
Growth Performance ◽  
Diphenyl Ether ◽  
Oxidant Stress ◽  
White Blood Cells ◽  
Abdominal Fat ◽  
Environmental Pollutant ◽  
Liver And Kidney ◽  
Bde 209 ◽  
Blood Profiles

Decabrominated diphenyl ether (BDE-209) is widely used as a flame retardant and is detected at high levels in the environment. Its toxicities have been reported and have attracted attention. In the present study, broilers were used to determine the response in growth performance, carcass traits, meat quality, blood profiles and antioxidant system to BDE-209 exposure at doses of 0, 0.02, 0.4 and 4 mg/kg. The results showed that BDE-209 exposure at levels of 0.02 or 0.4 mg/kg increased feed intake and decreased feed efficiency. BDE-209 altered the blood profiles, such as reducing the numbers of white blood cells, lymphocytes and neutrophilic granulocytes. As compared with the control, BDE-209 exposure significantly increased abdominal fat percentages of broilers at 64.9–159.5% and adversely affected the selected biochemical indicators, including alkaline phosphatase (ALP), aspartate aminotransferase (AST), alanine aminotransferase (ALT), creatine (CRE), which indicated its toxicity to liver and kidney functions. Moreover, BDE-209 exposure significantly increased plasma malondialdehyde (MDA) concentrations and decreased the activities of glutathione peroxidase (GSH-px) and superoxide dismutase (SOD), which implied aggravating oxidant stress and decline of antioxidant capacity in broilers. In conclusion, our data demonstrated that the environmental pollutant BDE-209 adversely influenced growth performance, increased the deposition of abdominal fat, impaired antioxidant capacity and the immune system and had potential toxicity to the liver and kidney of broilers.

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