Skin metastasis from papillary thyroid carcinoma: A rare case with an unusual clinical presentation

2020 ◽  
Vol 61 (3) ◽  
Author(s):  
Sarah Hsin Cheng ◽  
Stephen Chu‐Sung Hu
2021 ◽  
pp. 103032
Author(s):  
Nurul Anis Mohd Fauzi ◽  
Noor Idayu Ibrahim ◽  
Wan Faiziah Wan Abdul Rahman ◽  
Sharifah Emilia Tuan Sharif ◽  
Muhammad Nasri Abu Bakar ◽  
...  

2012 ◽  
Vol 2012 ◽  
pp. 1-4 ◽  
Author(s):  
Vijayraj S. Patil ◽  
Abhishek Vijayakumar ◽  
Neelamma Natikar

Papillary thyroid carcinoma is the most common thyroid malignancy, accounting for 80% of all thyroid cancers. The most common presentation of thyroid cancer is an asymptomatic thyroid mass or a nodule. Usually as thyroid enlarges, it extends in to mediastinum. Papillary thyroid carcinoma presentation as multiple true cystic swelling extending from neck to anterior chest wall in subcutaneous plane is not present in the literature. We present a rare case of cystic papillary thyroid carcinoma which is presented as subcutaneous swelling with sinus formation.


2017 ◽  
Vol 26 (5) ◽  
pp. 459-463 ◽  
Author(s):  
Haihui Liao ◽  
Ashraf Khan ◽  
Patricia M. Miron ◽  
Kristine M. Cornejo

Mammary analogue secretory carcinoma (MASC) harboring ETV6 gene rearrangements was first described in the salivary gland with a relatively favorable prognosis and a possible molecular therapeutic target with pan-Trk inhibitors. Recently, primary MASC of the thyroid gland has been reported. We report a case of a 4.0 cm MASC arising from the left thyroid of a 58-year-old female with extrathyroidal extension. Initially, it was diagnosed by fine needle aspiration as suspicious for papillary thyroid carcinoma (PTC) and subsequently called a poorly differentiated carcinoma on resection. A final diagnosis of primary MASC of the thyroid was confirmed after an expanded immunohistochemical panel and identification of an ETV6 gene rearrangement by fluorescence in situ hybridization. Morphologically, the tumor was composed of solid, microcystic and focally papillary growth with dense fibrotic stroma and necrosis. Overlapping cytological features with PTC were identified, including foci of enlarged cells with irregular nuclear membranes/grooves. However, most of the cells contained prominent nucleoli with intraluminal and intracytoplasmic eosinophilic secretions. Immunohistochemically, the tumor cells were strongly positive for pancytokeratin, cytokeratin 7, PAX8, mammaglobin, and GCDFP-15, with rare staining for GATA3 and S100 and negative for TTF-1 and thyroglobulin. We report a rare case of a primary thyroid MASC, initially misdiagnosed as PTC. Pathologists should be aware of this entity and, given the similarities to PTC, have a high index of suspicion, prompting the addition of immunohistochemical and molecular studies. Furthermore, an accurate diagnosis is important because of the possible prognostic and treatment implications.


Author(s):  
Savita Saharan ◽  
Ranjana Solanki ◽  
Deepak Saharan

<p>Medullary thyroid carcinoma and papillary thyroid carcinoma are two distinct types of thyroid carcinoma having different cellular origin. The simultaneous occurrence of two distinct neoplasms termed “collision tumour” and it is a rare entity. Sometimes the medullary component does not show calcitonin positivity and hence this becomes a very rare entity. Herein we describe a very rare case of simultaneous occurrence of calcitonin negative medullary thyroid carcinoma and papillary thyroid carcinoma.</p>


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