Reflectance confocal microscopy as a new diagnostic tool in transformed mycosis fungoides

2020 ◽  
Vol 61 (3) ◽  
Author(s):  
Bruna Melhoranse Gouveia ◽  
Jillian Wells ◽  
Jennifer Kim ◽  
Marco Ardigó ◽  
Germana Consuegra ◽  
...  
Keyword(s):  
Confocal Microscopy ◽  
Mycosis Fungoides ◽  
Diagnostic Tool ◽  
Reflectance Confocal Microscopy

scholarly journals Reflectance Confocal Microscopy as New Diagnostic Tool in Folliculotropic Mycosis Fungoides

2017 ◽  
Vol 4 (2) ◽  
pp. 118-121 ◽  
Author(s):  
Gabriella Fabbrocini ◽  
Caterina Mazzella ◽  
Mariateresa Cantelli ◽  
Antonello Baldo ◽  
Daniela Russo ◽  
...  
Keyword(s):  
Confocal Microscopy ◽  
Mycosis Fungoides ◽  
Diagnostic Tool ◽  
Reflectance Confocal Microscopy

scholarly journals The Differential Diagnosis of Hypopigmented Mycosis Fungoides and Vitiligo With Reflectance Confocal Microscopy: A Preliminary Study

2021 ◽  
Vol 7 ◽  
Author(s):  
Huaxu Liu ◽  
Leilei Wang ◽  
Yan Lin ◽  
Xiaofeng Shan ◽  
Min Gao
Keyword(s):  
Differential Diagnosis ◽  
Confocal Microscopy ◽  
Mycosis Fungoides ◽  
Early Stage ◽  
Reflectance Confocal Microscopy ◽  
Inflammatory Conditions ◽  
Dark Space ◽  
Superficial Dermis ◽  
Melanin Contents

Objective: To investigate the role of reflectance confocal microscopy (RCM) in the differential diagnosis of hypopigmented mycosis fungoides (HMF) and vitiligo.Methods: Cases with persistent hypopigmented patches, suspicious of early stage vitiligo, or HMF were imaged with RCM. The melanin contents and inflammatory conditions of the epidermis and superficial dermis of the lesions were compared with the same layers of the adjacent skin, and then, the imaged lesions were biopsied and analyzed by histology.Results: 15 cases were enrolled in this study, and based on the RCM findings, there was just slight or moderate reduction of melanin but no melanin absence in the basal cell layer of HMF lesions. The finding of monomorphous weakly refractile, oval to round cells on the basis of vesicle-like dark space was clearly elucidated in the epidermis of the lesions by RCM, which indicates the Pautrier's microabscesses on histopathology. Among those 15 cases, 13 cases were identified as HMF, and the other two cases were vitiligo, based on RCM findings, which were confirmed by histology analysis.Conclusions: The RCM findings correlated well with histology results in the screening of HMF, which indicates the RCM is an important tool in the early detection and differential diagnosis of HMF.

scholarly journals Reflectance confocal microscopy as a diagnostic tool for mastocytoma in children

2020 ◽  
Vol 83 (6) ◽  
pp. 1781-1784
Author(s):  
Xiangjie An ◽  
Maher Al-Muriesh ◽  
Bilal Abdul-Fattah ◽  
Yaoying Gao ◽  
Juan Tao ◽  
...  
Keyword(s):  
Confocal Microscopy ◽  
Diagnostic Tool ◽  
Reflectance Confocal Microscopy

scholarly journals Mycosis fungoides: reflectance confocal microscopy and its role in the diagnosis

2018 ◽  
Vol 38 (1) ◽  
Author(s):  
Ana Carolina Porto ◽  
Tatiana Pinto Blumetti ◽  
Adriana Silveira Pessoa Mendes ◽  
João Pedreira Duprat Neto ◽  
Gisele Gargantini Rezze ◽  
...  
Keyword(s):  
Confocal Microscopy ◽  
Mycosis Fungoides ◽  
Reflectance Confocal Microscopy

scholarly journals Lichenoid Keratosis: A Clinical Trap without Secrets for Reflectance Confocal Microscopy

2020 ◽  
Vol 12 (1) ◽  
pp. 47-51
Author(s):  
Sara Mazzilli ◽  
Terenzio Cosio ◽  
Elena Campione ◽  
Salvador Gonzalez ◽  
Caterina Lanna ◽  
...  
Keyword(s):  
Confocal Microscopy ◽  
Histological Examination ◽  
Lichen Planus ◽  
Diagnostic Tool ◽  
Accurate Diagnosis ◽  
Reflectance Confocal Microscopy

Lichenoid keratosis, also defined as benign lichenoid keratosis, was reclassified as lichen planus-like keratosis by Shapiro and Ackerman. Clinical and dermoscopic features of lichen planus-like keratosis can vary, often not providing useful and necessary information to perform an accurate diagnosis without performing a biopsy or histological examination. We describe 2 difficult to detect lichen planus-like keratosis cases in which we performed reflectance confocal microscopy. We underline the usefulness of this noninvasive diagnostic tool in the unclear cases of lichen planus-like keratosis.

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