Systematic review and meta‐analysis of surgical site infection following Mohs surgery without prophylactic antibiotics

2019 ◽  
Vol 60 (4) ◽  
pp. 340-342 ◽  
Author(s):  
Harvey Smith ◽  
Kate Borchard ◽  
Paul Cherian ◽  
Carl Vinciullo
Keyword(s):  
Systematic Review ◽  
Surgical Site Infection ◽  
Meta Analysis ◽  
Prophylactic Antibiotics ◽  
Site Infection ◽  
Mohs Surgery

scholarly journals Antibiotic Prophylaxis against Surgical Site Infection after Open Hernia Surgery: A Systematic Review and Meta-Analysis

2021 ◽  
pp. 1-13
Author(s):  
Lolwah Al Riyees ◽  
Wedad Al Madani ◽  
Nistren Firwana ◽  
Hanan H. Balkhy ◽  
Mazen Ferwana ◽  
...  
Keyword(s):  
Systematic Review ◽  
Hernia Repair ◽  
Surgical Site Infection ◽  
Antibiotic Prophylaxis ◽  
Meta Analysis ◽  
Prophylactic Antibiotics ◽  
Site Infection ◽  
Hernia Surgery ◽  
Significant Difference

<b><i>Objective:</i></b> The role of antibiotic prophylaxis (AP) in the prevention of surgical site infection (SSI) after hernia repair is debated. We conducted this systematic review and meta-analysis to assess the evidence on the value of prophylactic antibiotics in reducing the risks of SSI after open hernia surgery. <b><i>Methods:</i></b> We ran an online and manual search to identify relevant randomized controlled trials that compared prophylactic antibiotics to nonantibiotic controls in patients undergoing open surgical hernia repair. Data on SSI risk were extracted and pooled as risk ratios (RRs) with 95% confidence intervals (95% CIs), using RevMan software. We further used the Cochrane risk of bias tool and GRADE assessment to evaluate the quality of generated evidence. <b><i>Results:</i></b> Twenty-nine studies (<i>N</i> = 8,616 patients) were included in the current analysis. Antibiotic prophylaxis reduced the risk of SSI in open hernia repair patients (RR = 0.65, 95% CI = 0.53, 0.79). Subgroup analysis showed a significant benefit for antibiotics in mesh repair patients (RR = 0.60, 95% CI = 0.48, 0.76) yet no significant difference in SSI risk after herniorrhaphy (RR = 0.86, 95% CI = 0.54, 1.36). In addition, AP was associated with a significant reduction in superficial SSI risk (RR = 0.56, 95% CI = 0.43, 0.72) but not deep SSI (RR = 0.70, 95% CI = 0.30, 1.62). Further analysis showed a significant reduction in SSI risk with amoxicillin/clavulanic acid and cefazolin but not with cefuroxime. <b><i>Conclusion:</i></b> The present meta-analysis suggests that AP is beneficial prior to open mesh hernia repair. However, the quality of evidence was low, and further well-designed trials are needed.

scholarly journals Surgical site infection in mesh repair for ventral hernia in contaminated field: A systematic review and meta-analysis

2021 ◽  
Vol 63 ◽  
pp. 102173
Author(s):  
Mohamed Maatouk ◽  
Yacine Ben Safta ◽  
Aymen Mabrouk ◽  
Ghassen Hamdi Kbir ◽  
Anis Ben Dhaou ◽  
...  
Keyword(s):  
Systematic Review ◽  
Surgical Site Infection ◽  
Ventral Hernia ◽  
Mesh Repair ◽  
Meta Analysis ◽  
Site Infection ◽  
Contaminated Field

scholarly journals Surgical site infection and its associated factors in Ethiopia: a systematic review and meta-analysis

BMC Surgery ◽  
2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Wondimeneh Shibabaw Shiferaw ◽  
Yared Asmare Aynalem ◽  
Tadesse Yirga Akalu ◽  
Pammla Margaret Petrucka
Keyword(s):  
Systematic Review ◽  
Surgical Site Infection ◽  
Associated Factors ◽  
Meta Analysis ◽  
Site Infection
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