Nicotinamide and skin cancer chemoprevention: The jury is still out

2017 ◽  
Vol 59 (1) ◽  
pp. 6-9 ◽  
Author(s):  
Stephen J Gilmore
Keyword(s):  
Skin Cancer ◽  
Cancer Chemoprevention

Oral nicotinamide: The role in skin cancer chemoprevention

2021 ◽  
Author(s):  
Serena Giacalone ◽  
Cristina B. Spigariolo ◽  
Paolo Bortoluzzi ◽  
Gianluca Nazzaro
Keyword(s):  
Skin Cancer ◽  
Cancer Chemoprevention

Combination of UVB Absorbing Titanium Dioxide and Quercetin Nanogel for Skin Cancer Chemoprevention

2019 ◽  
Vol 20 (6) ◽  
Author(s):  
Arvind Bagde ◽  
Ketan Patel ◽  
Arindam Mondal ◽  
Shallu Kutlehria ◽  
Nusrat Chowdhury ◽  
...  
Keyword(s):  
Titanium Dioxide ◽  
Skin Cancer ◽  
Cancer Chemoprevention

scholarly journals New Enlightenment of Skin Cancer Chemoprevention through Phytochemicals:In VitroandIn VivoStudies and the Underlying Mechanisms

2014 ◽  
Vol 2014 ◽  
pp. 1-18 ◽  
Author(s):  
Madhulika Singh ◽  
Shankar Suman ◽  
Yogeshwer Shukla
Keyword(s):  
Skin Cancer ◽  
Cell Cycle Progression ◽  
Molecular Mechanisms ◽  
Cancer Chemoprevention ◽  
Chemopreventive Agents ◽  
Novel Approach ◽  
Comprehensive Knowledge ◽  
Underlying Mechanisms

Skin cancer is still a major cause of morbidity and mortality worldwide. Skin overexposure to ultraviolet irradiations, chemicals, and several viruses has a capability to cause severe skin-related disorders including immunosuppression and skin cancer. These factors act in sequence at various steps of skin carcinogenesis via initiation, promotion, and/or progression. These days cancer chemoprevention is recognized as the most hopeful and novel approach to prevent, inhibit, or reverse the processes of carcinogenesis by intervention with natural products. Phytochemicals have antioxidant, antimutagenic, anticarcinogenic, and carcinogen detoxification capabilities thereby considered as efficient chemopreventive agents. Considerable efforts have been done to identify the phytochemicals which may possibly act on one or several molecular targets that modulate cellular processes such as inflammation, immunity, cell cycle progression, and apoptosis. Till date several phytochemicals in the light of chemoprevention have been studied by using suitable skin carcinogenicin vitroandin vivomodels and proven as beneficial for prevention of skin cancer. This revision presents a comprehensive knowledge and the main molecular mechanisms of actions of various phytochemicals in the chemoprevention of skin cancer.

A Phase 3 Randomized Trial of Nicotinamide for Skin-Cancer Chemoprevention

2015 ◽  
Vol 373 (17) ◽  
pp. 1618-1626 ◽  
Author(s):  
Andrew C. Chen ◽  
Andrew J. Martin ◽  
Bonita Choy ◽  
Pablo Fernández-Peñas ◽  
Robyn A. Dalziell ◽  
...  
Keyword(s):  
Skin Cancer ◽  
Randomized Trial ◽  
Cancer Chemoprevention ◽  
Phase 3

scholarly journals Nicotinamide for skin cancer chemoprevention: effects of nicotinamide on melanoma in vitro and in vivo

2020 ◽  
Vol 19 (2) ◽  
pp. 171-179 ◽  
Author(s):  
Rashi Malesu ◽  
Andrew J. Martin ◽  
J. Guy Lyons ◽  
Richard A. Scolyer ◽  
Andrew C. Chen ◽  
...  
Keyword(s):  
Skin Cancer ◽  
Cancer Chemoprevention ◽  
Tumour Infiltrating Lymphocytes ◽  
Infiltrating Lymphocytes

Nicotinamide is chemopreventive against keratinocyte cancers but its effects on melanoma are unknown. Clinically-achievable nicotinamide doses do not enhance melanoma viability, proliferation or invasion and enhance tumour-infiltrating lymphocytes.

Skin Cancer Chemoprevention: Current Status and Future Potential

2011 ◽  
pp. 259-294
Author(s):  
Imtiaz A. Siddiqui ◽  
Vaqar M. Adhami ◽  
Hasan Mukhtar
Keyword(s):  
Skin Cancer ◽  
Cancer Chemoprevention ◽  
Current Status ◽  
Future Potential
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