Prevalence of striae gravidarum in a multi-ethnic Asian population and the associated risk factors

2017 ◽  
Vol 58 (3) ◽  
pp. e154-e155
Author(s):  
Lydia Tang-Lin ◽  
Hui M Liew ◽  
Mark JA Koh ◽  
John C Allen ◽  
Thiam C Tan
Keyword(s):  
Risk Factors ◽  
Asian Population ◽  
Associated Risk Factors ◽  
Striae Gravidarum

Evaluating serum elastin levels in striae gravidarum

2019 ◽  
Vol 45 (1) ◽  
pp. 76-82
Author(s):  
Beril Gürlek ◽  
Ülkü Mete Ural ◽  
Sibel Tuğcugil ◽  
Medeni Arpa ◽  
Özgür Önal
Keyword(s):  
Risk Factors ◽  
Pregnant Women ◽  
Prospective Observational Study ◽  
Personal Characteristics ◽  
Active Phase ◽  
Controlled Trials ◽  
Blood Samples ◽  
Associated Risk Factors ◽  
Striae Gravidarum ◽  
In Pregnancy

Abstract Objective Striae gravidarum (SG) is the most common dermatological defect in pregnancy leading to cosmetic anxiety with unknown etiopathogenesis. The aim of the study was to analyze the relation between serum elastin levels and striae and identify possible independent associated risk factors. Materials and methods This was a prospective observational study. In total, 138 primipara pregnant women were examined before delivery. Participants were separated into two groups according to the presence of SG. Striae assessment was performed according to Davey score. Before the active phase of labor patients were physically examined and blood samples were collected. Personal characteristics, features of birth, skin findings and serum elastin levels were compared between groups. Results Term pregnant women with SG had significantly higher serum elastin levels than those without SG (99.46 ± 32.92 vs. 88.36 ± 19.12, respectively; p = 0.018). Conclusions Serum elastin levels were increased in women with SG. However, the newly synthesized elastin may not be functional as it is thin and disorganized. Therefore, increased elastin production may not prevent the formation of striae. This finding may provide an impetus to explore the pathomechanisms of striae. Further controlled trials are warranted to determine the clinical significance of serum elastin levels in the formation of SG.

scholarly journals Risk factors of asthma in the Asian population: a systematic review and meta-analysis

2021 ◽  
Vol 40 (1) ◽  
Author(s):  
Yang Yie Sio ◽  
Fook Tim Chew
Keyword(s):  
Risk Factors ◽  
Systematic Review ◽  
Family History ◽  
Meta Analysis ◽  
Random Effect ◽  
Asian Population ◽  
Related Risk ◽  
The Family ◽  
History Of ◽  
Associated Risk Factors

Abstract Background and objective An increasing trend of asthma prevalence was observed in Asia; however, contributions of environmental and host-related risk factors to the development of this disease remain uncertain. This study aimed to perform a systematic review and meta-analysis for asthma-associated risk factors reported in Asia. Methods We systematically searched three public databases (Web of Science, PubMed, and Scopus) in Feb 2021. We only included articles that reported environmental and host-related risk factors associated with asthma in the Asian population. Random-effect meta-analyses were conducted for frequently reported asthma-associated risk factors to provide an overall risk estimate of asthma development. Results Of 4030 records obtained from public databases, 289 articles were selected for review. The most frequently reported asthma-associated risk factor was the family history of allergy-related conditions. The random-effect asthma risk estimates (pooled odds ratio, OR) were 4.66 (95% confidence interval (CI): 3.73–5.82) for the family history of asthma, 3.50 (95% CI: 2.62–4.67) for the family history of atopy, 3.57 (95% CI: 3.03–4.22) for the family history of any allergic diseases, 1.96 (95% CI: 1.47–2.61) for the family history of allergic rhinitis, and 2.75 (95% CI: 1.12–6.76) for the family history of atopic dermatitis. For housing-related factors, including the presence of mold, mold spots, mold odor, cockroach, water damage, and incense burning, the random-effect pooled OR ranged from 1.43 to 1.73. Other risk factors with significant pooled OR for asthma development included male gender (1.30, 95% CI: 1.23–1.38), cigarette smoke exposure (1.44, 95% CI: 1.30–1.60), cigarette smoking (1.66, 95% CI: 1.44–1.90), body mass index (BMI)–related parameters (pooled OR ranged from 1.06 to 2.02), various types of air pollution (NO2, PM10, and O3; pooled OR ranged from 1.03 to 1.22), and pre- and perinatal factors (low birth weight, preterm birth, and cesarean section; pooled OR ranged from 1.14 to 1.32). Conclusions The family history of asthma was the most frequently reported risk factor for asthma development in Asia with the highest risk estimate for asthma development. This suggests a major role of the genetic component in asthma pathogenesis. Further study on asthma genetics is required to improve the current understanding of asthma etiology.

scholarly journals Orthostatic hypotension: prevalence and associated risk factors among the ambulatory elderly in an Asian population

2016 ◽  
Vol 57 (8) ◽  
pp. 444-451 ◽  
Author(s):  
QO Zhu ◽  
CS Tan ◽  
HL Tan ◽  
RG Wong ◽  
CS Joshi ◽  
...  
Keyword(s):  
Risk Factors ◽  
Orthostatic Hypotension ◽  
Asian Population ◽  
Associated Risk Factors

Six-year incidence and systemic associations of retinopathy in a multi-ethnic Asian population without diabetes

2021 ◽  
pp. bjophthalmol-2020-318126
Author(s):  
Preeti Gupta ◽  
Ecosse Luc Lamoureux ◽  
Charumathi Sabanayagam ◽  
Yih-Chung Tham ◽  
Gavin Tan ◽  
...  
Keyword(s):  
Risk Factors ◽  
Multivariable Analysis ◽  
Density Lipoprotein ◽  
Asian Population ◽  
Microvascular Dysfunction ◽  
Population Based ◽  
Retinal Artery ◽  
Associated Risk Factors ◽  
Disease Study

PurposeWe described the 6-year incidence and changes of retinopathy, and their associated risk factors in a multi-ethnic Asian population without diabetes.MethodsWe included 4374 participants with non-diabetes from a population-based cohort, the Singapore Epidemiology of Eye Disease Study, with gradable retinal photographs at baseline and 6-year follow-up visit. Retinopathy was assessed according to the modified Airlie House classification system.ResultsOver the 6-year period, the cumulative rates were 2.5% (106/4279) for retinopathy incidence, 1.0% (1/95) for retinopathy progression and 68.4% (65/95) for retinopathy regression. In multivariable analysis, higher diastolic blood pressure (DBP) (risk ratio (RR)=1.02; 95% CI: 1.00 to 1.04; per 10 mm Hg increase in DBP) and wider retinal arteriolar calibre (RR=1.36; 95% CI: 1.13 to 1.63; per SD increase in central retinal artery equivalent) were associated with higher risk of incident retinopathy, while higher level of high-density lipoprotein (HDL) was associated with lower risk of incident retinopathy (RR=0.56; 95% CI: 0.32 to 0.99; per mmol/L increase in HDL). Compared with Chinese, Malays were more likely to have retinopathy regression (RR=1.63; 95% CI: 1.20 to 2.22), while overweight (RR=0.47; 95% CI: 0.26 to 0.84) and higher glycosylated haemoglobin (HbA1c) level (RR=0.58; 95% CI: 0.37 to 0.93; per per cent increase in HbA1c) were associated with lower likelihood of retinopathy regression.ConclusionRisk of developing retinopathy in Asians without diabetes is generally low. However, regression of retinopathy over time is common, suggesting that these retinopathy signs may reflect subclinical reversible microvascular dysfunction. Several metabolic risk factors are associated with incidence or regression of retinopathy, suggesting that good metabolic control may still be important in the management of non-diabetic retinopathy.

Bone mineral density and associated risk factors: in healthy Indian population

2016 ◽  
Author(s):  
Swati Waghdhare ◽  
Neelam Kaushal ◽  
Rajinder K Jalali ◽  
Divya Vohora ◽  
Sujeet Jha
Keyword(s):  
Risk Factors ◽  
Bone Mineral Density ◽  
Bone Mineral ◽  
Indian Population ◽  
Mineral Density ◽  
Associated Risk Factors

Causes and associated risk factors of heart failure patients in Aljouf region of Saudi Arabia

2021 ◽  
pp. 185-189
Author(s):  
Md Sheikh ◽  
Manahel Alotaibi ◽  
Nouf Almutairi ◽  
Eid Aljohani ◽  
Omar Alruwaili ◽  
...  
Keyword(s):  
Risk Factors ◽  
Heart Failure ◽  
Saudi Arabia ◽  
Heart Failure Patients ◽  
Associated Risk Factors
Sign in / Sign up

Export Citation Format

Share Document