Clinical and histopathological characteristics of extra-facial basal cell carcinoma: Analysis of 35 patients at the Chonbuk National University Hospital in Korea

2013 ◽  
Vol 55 (4) ◽  
pp. e65-e68 ◽  
Author(s):  
Si-Gyun Roh ◽  
Jin Park ◽  
Ki-Hun Song ◽  
Kyung-Hwa Nam ◽  
Seok-Kweon Yun ◽  
...  
Keyword(s):  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Basal Cell ◽  
University Hospital ◽  
National University

scholarly journals Differences in age and topographic distribution of the different histological subtypes of basal cell carcinoma, Taubaté (SP), Brazil

2013 ◽  
Vol 88 (5) ◽  
pp. 726-730 ◽  
Author(s):  
Flavia Regina Ferreira ◽  
Bruna da Costa Pevide ◽  
Rafaela Fabri Rodrigues ◽  
Luiz Fernando Costa Nascimento ◽  
Marcia Lanzoni de Alvarenga Lira
Keyword(s):  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Basal Cell ◽  
Skin Color ◽  
Age Of Onset ◽  
The Body ◽  
University Hospital ◽  
Histological Subtype ◽  
Histological Subtypes ◽  
The Mean

BACKGROUND: Basal cell carcinoma is the most common form of cancer in humans. OBJECTIVES: To identify the epidemiology of basal cell carcinoma in Taubaté-SP and verify a possible association between topography and the different histological subtypes of this tumor. METHODS: This was a cross-sectional study conducted at The University Hospital of Taubaté between 01/01/08 and 12/31/09. The study included patients with a confirmed diagnosis of basal cell carcinoma, of both genders, without age restrictions. The variables studied were incidence of basal cell carcinoma, topography, histological subtype, skin color, age and gender. We employed the chi-square test to identify the association between histological subtype and topography, and the student's t test to compare the mean age of onset for the different histological subtypes. RESULTS: The study included 239 individuals. The mean age of the sample was 68.0 years. Male subjects (57.7%) and whites (87.1%) predominated in the study. The predominant histological subtype was nodular (34.7%), followed by the superficial subtype. The most frequent sites of involvement were the head and neck (areas exposed to light), with predominance of the nasal region. The superficial subtype was an exception, as it showed a strong association with unexposed areas like the trunk. The mean age of onset of superficial basal cell carcinoma also differed from that of the other histological subtypes, 63.0 and 69.0 years, respectively. CONCLUSION: The results of this study suggest an association of the superficial histological subtype with younger patients and unexposed areas of the body, linking this type of tumor with a pattern of intermittent sun exposure, more similar to the standard photocarcinogenesis of melanoma.

scholarly journals A Case of Cystic Basal Cell Carcinoma Which Shows a Homogenous Blue/Black Area under Dermatoscopy

2011 ◽  
Vol 2011 ◽  
pp. 1-4 ◽  
Author(s):  
Akihiro Yoneta ◽  
Kohei Horimoto ◽  
Keiko Nakahashi ◽  
Satoru Mori ◽  
Kazuo Maeda ◽  
...  
Keyword(s):  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Basal Cell ◽  
Skin Tumor ◽  
University Hospital ◽  
Common Skin ◽  
Black Area ◽  
Medical University ◽  
Cystic Type

Basal cell carcinoma (BCC) is the most common skin tumor and contains several different histopathological types. Here, we report a case of cystic basal cell carcinoma, which is relatively rare and might be clinically misdiagnosed. A dermatoscopic examination of the case revealed a homogenous blue/black area usually not seen in BCC. We reviewed 102 BCC cases resected and diagnosed at Sapporo Medical University Hospital between April 2005 and March 2010. Among them, only three were the cystic type.

scholarly journals Clinical and genetic profiling of nevoid basal cell carcinoma syndrome in Korean patients by whole-exome sequencing

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Boram Kim ◽  
Man Jin Kim ◽  
Keunyoung Hur ◽  
Seong Jin Jo ◽  
Jung Min Ko ◽  
...  
Keyword(s):  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Exome Sequencing ◽  
Whole Exome Sequencing ◽  
Basal Cell ◽  
University Hospital ◽  
Genetic Profiling ◽  
Korean Patients ◽  
Pathogenic Variants ◽  
Whole Exome

AbstractNevoid basal cell carcinoma syndrome (NBCCS) is mainly characterised by multiple basal cell carcinomas (BCCs) caused by PTCH1, PTCH2, and SUFU. However, clinical and genetic data on Asian NBCCS patients are limited. We aimed to analyse the clinical phenotypes and genetic spectrum of Korean patients with NBCCS. Fifteen patients with NBCCS at Seoul National University Hospital were included, and their clinical data were analysed. Whole-exome sequencing and/or multiplex ligation-dependent probe amplification using peripheral blood were performed to identify genetic causes. Genetic analysis revealed that 73.3% (11/15) of the patients carried 9 pathogenic variants, only in the PTCH1 gene. Variants of uncertain significance (VUS) and likely benign were also detected in 2 (13.3%) and 2 (13.3%) patients, respectively. BCCs were found in the majority of the cases (93.3%) and the number of BCCs increased with age (ρ = 0.595, P = 0.019). This study revealed that PTCH1 pathogenic variants were the main cause of NBCCS in Korean patients. As BCCs are commonly detected, a periodic dermatologic examination is recommended. Finally, our results support the addition of genetic screening to the existing criteria for NBCCS diagnosis.

scholarly journals Advanced basal cell carcinomas of the face: A Moroccan series

2021 ◽  
Vol 12 (2) ◽  
pp. 135-139
Author(s):  
Sara Elloudi ◽  
Aida Oulehri ◽  
Hanane Baybay ◽  
Zakia Douhi ◽  
Fatima Zahra Mernissi
Keyword(s):  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Basal Cell ◽  
Rural Areas ◽  
University Hospital ◽  
Temporal Region ◽  
Dermatology Department ◽  
Skin Malignancy ◽  
The Face ◽  
The University

Background: Basal cell carcinoma (BCC) is the most common cutaneous skin malignancy. 85% of BCCs affect the face, a region particularly rich in noble organs. Although BCC progresses slowly, considerable local destruction and mutilation may be observed. Material and Methods: We performed a retrospective review of the database stored by our institution. All patients with histologically confirmed mutilating basal cell carcinoma of the face hospitalized at the dermatology department of the university hospital in Fez, Morocco, from 2015 through 2020 were evaluated. Results: Nine patients were included, with the tumors located in the lips, temporal region, orbital region, and cheeks, with sizes varying from 5 to 11 cm. Conclusion: In the series, we were able to highlight the high-risk character of the subpopulation living in rural areas and the role of smoking as a major risk factor.

A Case Report of Complicated Multiple Facial Basal Cell Carcinoma Treatment in a Young Woman

2011 ◽  
Vol 11 (1) ◽  
pp. 156-158
Author(s):  
Aleksandrs Derjabo ◽  
Ingrida Cema ◽  
Sergejs Isajevs ◽  
Simona Donina
Keyword(s):  
Case Report ◽  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Young Woman ◽  
Basal Cell ◽  
Disease Free Survival ◽  
University Hospital ◽  
Free Survival ◽  
Basal Cell Carcinomas ◽  
Oncology Centre

A Case Report of Complicated Multiple Facial Basal Cell Carcinoma Treatment in a Young Woman A 36-year-old woman was consulted in Riga Eastern Clinical University Hospital Latvian Oncology centre Outpatient Department with multiple histology-proven basal cell carcinomas. The patient was treated with diode laser 980 nm and immunotherapy and had 5 years disease free survival.

scholarly journals Basal Cell Carcinoma, Odontogenic Cysts, Brain and Skeletal Abnormalities (Gorlin Goltz) Syndrome in a 46-Year-Old Woman

2018 ◽  
Vol 32 (2) ◽  
pp. 38-42
Author(s):  
Diane Clarice D. Magbuhat ◽  
Jeannette Marie S. Matsuo ◽  
Rhodieleen Anne R. De la Cruz
Keyword(s):  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Basal Cell ◽  
Cervical Vertebrae ◽  
University Hospital ◽  
Odontogenic Cysts ◽  
High Tendency ◽  
Orbital Mass ◽  
Skeletal Abnormalities ◽  
Goltz Syndrome

Objective: To present the case of a 46-year-old woman with basal cell carcinoma, odontogenic cysts, brain anomalies and skeletal abnormalities. Method:             Design:           Case Report             Setting:           Tertiary National University Hospital             Patient:           One Results: A 46-year-old woman consulted for a non-healing, necrotic left orbital ulcer that started as a skin-colored, papilla-like lesion on the upper eyelid. There were also hyperpigmented lesions with ill-defined borders over both paranasal areas. Tissue biopsies revealed basal cell carcinoma. Radiologic imaging showed cystic lesions in the mandible, straightening of cervical vertebrae and calcifications of the falx cerebri, tentorium cerebelli, pineal gland and choroid plexus. Based on established major and minor clinical and radiologic criteria, we arrived at a diagnosis of Gorlin Goltz Syndrome or Nevoid Basal Cell Carcinoma Syndrome (NBCCS). She underwent wide excision of the left orbital mass with exenteration, excision of left and right paranasal masses, left total parotidectomy with facial nerve preservation, enucleation of mandibular cyst, and cervicofacial reconstruction with skin grafts of the left orbital area and ala. Conclusion: NBCCS is a rare autosomal dominant disorder with a high tendency for neoplasms and developmental anomalies. Diagnosis can easily be missed if the physician is unaware of its classic but bizarre presentation. Early recognition and prompt specialist referral is very important in order to prevent complications and provide better prognosis. Patients should be reminded of the importance of follow-up as other presentations of the syndrome may manifest later in life, and family genetic screening and counseling should be undertaken. Keywords: Gorlin Goltz Syndrome; Nevoid Basal Cell Carcinoma Syndrome; odontogenic keratocyst

Ultrastructure of Mouse Basal Cell Carcinoma Exhibiting Sebaceous Differentiation

1980 ◽  
Vol 38 ◽  
pp. 738-739
Author(s):  
Victoria L. Wade ◽  
Winslow G. Sheldon ◽  
James W. Townsend ◽  
William Allaben
Keyword(s):  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Topical Application ◽  
Basal Cell ◽  
Sebaceous Gland ◽  
Rats And Mice ◽  
Mixed Tumors

Sebaceous gland tumors and other tumors exhibiting sebaceous differentiation have been described in humans (1,2,3). Tumors of the sebaceous gland can be induced in rats and mice following topical application of carcinogens (4), but spontaneous mixed tumors of basal cell origin rarely occur in mice.

Basal cell carcinoma of the nail bed in a Korean woman

2000 ◽  
Vol 39 (5) ◽  
pp. 397-398 ◽  
Author(s):  
Hyoung-Joo Kim ◽  
Youn-Soo Kim ◽  
Ki-Beom Suhr ◽  
Tae-Young Yoon ◽  
Jeung-Hoon Lee ◽  
...  
Keyword(s):  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Basal Cell ◽  
Korean Woman ◽  
Nail Bed
Sign in / Sign up

Export Citation Format

Share Document