Clinical significance and prognostic value of circulating B10 cells in colorectal cancer

2021 ◽  
Author(s):  
Zhaoyan Qiu ◽  
Qian Li ◽  
Yixun Lu ◽  
Qian Wang
Keyword(s):  
Colorectal Cancer ◽  
Clinical Significance ◽  
Prognostic Value ◽  
B10 Cells

Prognostic Value of Erythrocyte Sedimentation Rate in Patients with Colorectal Cancer

2008 ◽  
Vol 24 (5) ◽  
pp. 351
Author(s):  
Young Ki Kim ◽  
Seong Woo Hong ◽  
Jung Woo Chun ◽  
Yeo Goo Chang ◽  
In Wook Paik ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Erythrocyte Sedimentation Rate ◽  
Sedimentation Rate ◽  
Prognostic Value ◽  
Erythrocyte Sedimentation

scholarly journals Metastatic heterogeneity of the consensus molecular subtypes of colorectal cancer

2021 ◽  
Vol 6 (1) ◽  
Author(s):  
Peter W. Eide ◽  
Seyed H. Moosavi ◽  
Ina A. Eilertsen ◽  
Tuva H. Brunsell ◽  
Jonas Langerud ◽  
...  
Keyword(s):  
Gene Expression ◽  
Colorectal Cancer ◽  
Principal Components ◽  
Prognostic Value ◽  
Tumor Heterogeneity ◽  
Molecular Subtypes ◽  
R Package ◽  
Data Set ◽  
Primary Tumors ◽  
External Data

AbstractGene expression-based subtypes of colorectal cancer have clinical relevance, but the representativeness of primary tumors and the consensus molecular subtypes (CMS) for metastatic cancers is not well known. We investigated the metastatic heterogeneity of CMS. The best approach to subtype translation was delineated by comparisons of transcriptomic profiles from 317 primary tumors and 295 liver metastases, including multi-metastatic samples from 45 patients and 14 primary-metastasis sets. Associations were validated in an external data set (n = 618). Projection of metastases onto principal components of primary tumors showed that metastases were depleted of CMS1-immune/CMS3-metabolic signals, enriched for CMS4-mesenchymal/stromal signals, and heavily influenced by the microenvironment. The tailored CMS classifier (available in an updated version of the R package CMScaller) therefore implemented an approach to regress out the liver tissue background. The majority of classified metastases were either CMS2 or CMS4. Nonetheless, subtype switching and inter-metastatic CMS heterogeneity were frequent and increased with sampling intensity. Poor-prognostic value of CMS1/3 metastases was consistent in the context of intra-patient tumor heterogeneity.

scholarly journals 126P Prognostic value of blood-based fibrosis biomarkers in patients with metastatic colorectal cancer receiving chemotherapy and bevacizumab

2020 ◽  
Vol 31 ◽  
pp. S290
Author(s):  
N.I. Nissen ◽  
S. Kehlet ◽  
M.K. Boisen ◽  
M. Liljefors ◽  
C. Jensen ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Metastatic Colorectal Cancer ◽  
Prognostic Value

scholarly journals The prognostic value of KRAS mutations in patients with colorectal cancer

2012 ◽  
Vol 28 (5) ◽  
pp. 1579-1584 ◽  
Author(s):  
YASUHIRO INOUE ◽  
SUSUMU SAIGUSA ◽  
TAKASHI IWATA ◽  
YOSHINAGA OKUGAWA ◽  
YUJI TOIYAMA ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Prognostic Value ◽  
Kras Mutations
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