Diagnostic accuracy of urine cytokeratin 20 for bladder cancer: A meta‐analysis

2018 ◽  
Vol 15 (2) ◽  
pp. e11-e19 ◽  
Author(s):  
Yan Mi ◽  
Yinlong Zhao ◽  
Fang Shi ◽  
Mengmeng Zhang ◽  
Chunpeng Wang ◽  
...  
Keyword(s):  
Bladder Cancer ◽  
Diagnostic Accuracy ◽  
Meta Analysis ◽  
Cytokeratin 20

Diagnostic accuracy of magnetic resonance imaging for tumour staging of bladder cancer: systematic review and meta-analysis

2018 ◽  
Vol 122 (5) ◽  
pp. 744-753 ◽  
Author(s):  
Niket Gandhi ◽  
Satheesh Krishna ◽  
Christopher M. Booth ◽  
Rodney H. Breau ◽  
Trevor A. Flood ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Systematic Review ◽  
Bladder Cancer ◽  
Magnetic Resonance ◽  
Diagnostic Accuracy ◽  
Meta Analysis ◽  
Tumour Staging ◽  
Resonance Imaging

scholarly journals Diagnostic accuracy of the UBC� Rapid Test for bladder cancer: A meta‑analysis

2018 ◽  
Author(s):  
Pei Lu ◽  
Jianchun Cui ◽  
Keliang Chen ◽  
Qiang Lu ◽  
Jiexiu Zhang ◽  
...  
Keyword(s):  
Bladder Cancer ◽  
Diagnostic Accuracy ◽  
Meta Analysis ◽  
Rapid Test

Diagnostic accuracy of cytokeratin-19 fragment (CYFRA 21–1) for bladder cancer: a systematic review and meta-analysis

Tumor Biology ◽  
2015 ◽  
Vol 36 (5) ◽  
pp. 3137-3145 ◽  
Author(s):  
Yuan-Lan Huang ◽  
Jie Chen ◽  
Wei Yan ◽  
Ding Zang ◽  
Qin Qin ◽  
...  
Keyword(s):  
Systematic Review ◽  
Bladder Cancer ◽  
Diagnostic Accuracy ◽  
Meta Analysis ◽  
Cytokeratin 19 ◽  
Cytokeratin 19 Fragment

scholarly journals The Diagnostic Value of LncRNAs for Bladder Cancer: A Meta-Analysis

2021 ◽  
Author(s):  
Yuan Chen ◽  
Faiza Naz ◽  
Shi Fu ◽  
Mengran Shi ◽  
Haihao Li ◽  
...  
Keyword(s):  
Bladder Cancer ◽  
Diagnostic Accuracy ◽  
Likelihood Ratio ◽  
Sensitivity And Specificity ◽  
Odds Ratio ◽  
Meta Analysis ◽  
Positive Likelihood Ratio ◽  
Diagnostic Odds Ratio ◽  
Diagnostic Value ◽  
Cochrane Library

Abstract Background: In recent years, qualitative and quantitative analysis of LncRNA has been reported as a potential method for early diagnosis of bladder cancer, but the results from each research are insufficient and not completely consistent. This meta-analysis aims to evaluate the diagnostic value of LncRNA for BC.Methods: We conducted a diagnostic meta-analysis and the diagnostic significance of LncRNA in blood, urine and tumor tissues was discussed. We searched the PUBMED, EMABASE, and Cochrane Library until June 2020. The current meta-analysis was performed using Review Manager 5.2, Stata 16.0 and Meta-Disc 1.4 software. Results: A total of 18 researches involving early and/or advanced bladder cancer were finally included. The overall diagnostic accuracy was measured as follows: pooled sensitivity and specificity were 0.72 (95%CI:0.70, 0.73) and 0.76 (95%CI: 0.75, 0.78). Pooled positive likelihood ratio and negative likelihood ratio were 3.09 (95%CI: 2.66, 3.58) and 0.37 (95%CI: 0.33, 0.42). Combined diagnostic odds ratio was 9.43 (95%CI: 7.30, 12.20). A high diagnostic accuracy was demonstrated by the summary receiver operating characteristic curve, with area under the curve of 0.82 (95%CI: 0.78, 0.85). UCA1 and H19 had the best diagnostic effect, their diagnostic sensitivity and specificity were 80%, 79% and 79%, 73% respectively, the combined diagnostic odds ratio was 16.85 and 12.67 respectively.Conclusions: This meta-analysis suggests that LncRNA have great potential in the diagnosis of bladder cancer, UCA1 and H19 had the best diagnostic effect. LncRNA panel is the future development direction in the diagnosis of bladder cancer. However, larger sample researches are needed to further confirm our conclusion.

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