scholarly journals ABO blood group and the risk of cancer among middle‐aged people in T aiwan

2014 ◽  
Vol 11 (4) ◽  
Author(s):  
Ling‐Tzu Hsiao ◽  
Nai‐Jung Liu ◽  
San‐Lin You ◽  
Lee‐Ching Hwang
Keyword(s):  
Blood Group ◽  
Abo Blood Group ◽  
Middle Aged ◽  
Aged People ◽  
Risk Of Cancer

Prothrombotic State Induced by Middle-Distance Endurance Exercise in Middle-Aged Athletes

2018 ◽  
Vol 44 (08) ◽  
pp. 747-755 ◽  
Author(s):  
Gian Salvagno ◽  
Cantor Tarperi ◽  
Matteo Gelati ◽  
Martina Montagnana ◽  
Elisa Danese ◽  
...  
Keyword(s):  
Blood Coagulation ◽  
Blood Group ◽  
Thrombin Generation ◽  
Area Under The Curve ◽  
Abo Blood Group ◽  
Middle Aged ◽  
Endurance Running ◽  
Von Willebrand ◽  
The Impact ◽  
D Dimer

AbstractSince the impact of possible prothrombotic factors on blood coagulation resulting from exercise remains elusive, this study investigated the acute effects of middle-distance endurance running on blood coagulation parameters in middle-aged athletes. The study population consisted of 33 male endurance runners who were engaged in a 21.1 km run under competitive conditions. Blood samples were collected before the run, immediately after the run, and 3 hours after run completion. Samples were assessed for activated partial thromboplastin time (APTT), prothrombin time (PT), fibrinogen, D-dimer, factor VIII (FVIII), von Willebrand factor antigen (VWF:Ag), endogenous thrombin potential (area under the curve of thrombin generation [TGA-AUC]), and peak thrombin generation (TGA-PK). Post-run variations were expressed as delta (Δ). At baseline, APTT was found to be significantly associated with ABO blood group, VWF:Ag, and FVIII; fibrinogen with age; VWF:Ag with BMI, training regimen, and ABO blood group; APTT with FVIII; FVIII with VWF:Ag and ABO blood group; APTT with VWF:Ag; and TGA-PK with ABO blood group, PT, and TGA-AUC. Immediately after the run, statistically significant increases were observed for PT, D-dimer, VWF:Ag, and FVIII, while statistically significant reductions could be observed for APTT, TGA-AUC, and TGA-PK. Fibrinogen values remained unchanged. Significant correlations were observed between Δ VWF:Ag and Δ FVIII, Δ APTT and Δ VWF:Ag, Δ APTT and Δ FVIII, Δ TGA-AUC and Δ TGA-PK, and between Δ D-dimer and Δ TGA-AUC and Δ TGA-PK. No Δ variation was associated with running time. The results of this study seemingly suggest that middle-distance competitive running may evoke several prothrombotic changes in blood coagulation.

ABO blood group and risk of cancer: A register-based cohort study of 1.6 million blood donors

2016 ◽  
Vol 44 ◽  
pp. 40-43 ◽  
Author(s):  
Senthil K. Vasan ◽  
Jinseub Hwang ◽  
Klaus Rostgaard ◽  
Olof Nyrén ◽  
Henrik Ullum ◽  
...  
Keyword(s):  
Cohort Study ◽  
Blood Group ◽  
Blood Donors ◽  
Abo Blood Group ◽  
Risk Of Cancer

scholarly journals Determining the Association of Benign and Malignant Salivary Gland Tumours with ABO-Rh Blood Groups

2019 ◽  
Vol 27 (2) ◽  
pp. 154-160
Author(s):  
Mahbobeh Oroei
Keyword(s):  
Salivary Gland ◽  
Blood Group ◽  
Salivary Gland Tumor ◽  
Blood Groups ◽  
Abo Blood Group ◽  
Gland Tumor ◽  
Tumor Risk ◽  
Increased Risk ◽  
Risk Of Malignancy ◽  
Risk Of Cancer

Introduction Various studies have proposed that some ABO blood groups may be associated with increased risk of cancer. Hence, we decided to conduct this study to investigate the relationship between ABO-Rh blood group and risk of salivary gland tumor. Materials and Methods In this study, 190 patients with salivary gland tumor and 400 healthy persons were investigated. Demographical information including ABO blood group of both groups were collected and analyzed using the SPSS 18 version. Binary logistic regression (univariate and multivariate model) were applied with 95% confidence interval. Results The most common blood group in patients with salivary gland tumor was blood group O. There was no significant relationship between the ABO blood group and salivary gland tumor risk (All; p>0.05). The blood group O and A were the most abundant blood groups in patients with the malignant and benign salivary gland tumor respectively (46.6%, 35.7%).The risk of malignancy of tumor in the patients with blood group O was marginal (1.84; 95%CI: 0.96-3.53, p: 0.06).  Conclusion This study shows no relationship between ABO-Rh blood groups and salivary gland tumor risk. However, to reach a definitive conclusion about the risk of malignancy in blood group O, stronger studies are needed in the future.

scholarly journals Allele Frequency of ABO Blood Group Antigen and the Risk of Esophageal Cancer

2014 ◽  
Vol 2014 ◽  
pp. 1-6 ◽  
Author(s):  
Narender Kumar ◽  
Akhil Kapoor ◽  
Ashok Kalwar ◽  
Satya Narayan ◽  
Mukesh Kumar Singhal ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Blood Group ◽  
Squamous Cell ◽  
Gene Frequency ◽  
Abo Blood Group ◽  
Carcinoma Of The Esophagus ◽  
Significant Difference ◽  
Carcinoma Of Esophagus ◽  
Risk Of Cancer

Background. ABO blood group and risk of squamous cell carcinoma of esophagus have been reported by many studies, but there is no discipline that had provided association with the genotype and gene frequency by population statics.Methods. We conducted a case-control study on 480 patients with squamous cell carcinoma of the esophagus and 480 noncancer patients. ABO blood group was determined by presence of antigen with the help of monoclonal antibody. Chi-square test and odds ratio (OR) with 95% confidence intervals (CIs) were calculated by statistical methods, and gene frequencies were calculated by Hardy-Weinberg model.Results. We observed significant associations between ABO genotype and squamous cell carcinoma of esophagus. OR (95% CIs) was 1.69 (1.31–2.19) for presence of B antigen allele relative to its absence (P<0.0001); in female subgroup OR (95% CIs) observed at 1.84 (1.27–2.65) was statistically significant (P=0.001). SCC of esophagus shows significant difference in comparison to general population; blood group B is found to be higher in incidence (P=0.0001). Increased risk of cancer was observed with absence of Rh antigen (P=0.0001). Relatively increased gene frequency ofq[B] allele is observed more significantly in female cancer patients (P=0.003).Conclusion. Statistically significant association between squamous cell carcinoma of the esophagus and ABO and Rh genotype is identified by this study. Sex and anatomical site of cancer also present with statistically significant relative association. However, larger randomised trials are required to establish the hypothesis.

The Correlation Between ABO Blood Group and Neonatal Disease Severity

PEDIATRICS ◽  
2016 ◽  
Vol 137 (Supplement 3) ◽  
pp. 461A-461A
Author(s):  
Kacie E. McMahon ◽  
Jonathan K. Muraskas
Keyword(s):  
Disease Severity ◽  
Blood Group ◽  
Abo Blood Group ◽  
Neonatal Disease

Complex treatment of periodontitis: patient’s reaction to the therapy

2020 ◽  
Vol 25 (2) ◽  
pp. 97-100
Author(s):  
A. K. Iordanishvili ◽  
V. A. Guk ◽  
A. A. Golovko
Keyword(s):  
Elderly People ◽  
Periodontal Diseases ◽  
Personal Characteristics ◽  
The Elderly ◽  
Comprehensive Treatment ◽  
Complex Treatment ◽  
Middle Aged ◽  
Aged People ◽  
Dental Rehabilitation ◽  
Success Of Treatment

Relevance. The success of treatment of periodontal diseases directly depends on the patient’s response to the therapy, therefore, the characteristics of the person’s personal characteristics can affect both the effectiveness of treatment and the prevention of relapse of the disease.Purpose. To study the features of the internal picture of the disease in the process of complex treatment of adult patients suffering from chronic generalized periodontitis.Materials and methods. The generally accepted comprehensive treatment of chronic generalized periodontitis in 69 middle-aged and elderly men was carried out taking into account the personal response of patients Solovyov «Psychosensory-anatomical-functional maladaptation syndrome».Results. When patients were discharged from the hospital, there was a difference in the phenomena of maladaptation among the elderly and middle-aged: in middle-aged people, sufficient adaptation to the conditions of existence was determined; in elderly people, due to the existing comorbid pathology, a state of maladaptation was diagnosed, which was caused by the presence of complaints of defects in the dentition.Conclusion. In elderly people, as soon as possible after completion of treatment in a hospital, dental rehabilitation cannot be considered completed, which requires the adoption of organizational measures for their timely provision of dentures.

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