scholarly journals Incorporating Hardy-Weinberg Equilibrium Law to Enhance the Association Strength for Ordinal Trait Genetic Study

2015 ◽  
Vol 80 (2) ◽  
pp. 102-112 ◽  
Author(s):  
Wei Zhang ◽  
 Qizhai Li
Keyword(s):  
Genetic Study ◽  
Association Strength ◽  
Weinberg Equilibrium ◽  
Hardy Weinberg Equilibrium

Significance of Hardy-Weinberg Equilibrium in Case Control

2004 ◽  
Vol 73 (1) ◽  
pp. 95-95
Author(s):  
Hemant Kumar Bid ◽  
Rama D. Mittal
Keyword(s):  
Case Control ◽  
Weinberg Equilibrium ◽  
Hardy Weinberg Equilibrium

scholarly journals Underuse of Hardy-Weinberg equilibrium

2004 ◽  
Vol 66 (4) ◽  
pp. 1711 ◽  
Author(s):  
Gere Sunder-Plassmann ◽  
Manuela Födinger
Keyword(s):  
Weinberg Equilibrium ◽  
Hardy Weinberg Equilibrium

Teaching the Hardy-Weinberg Equilibrium: A 5E Lesson Plan

2017 ◽  
Vol 79 (4) ◽  
pp. 288-293
Author(s):  
Mike U. Smith
Keyword(s):  
Young People ◽  
Lesson Plan ◽  
Original Data ◽  
Good Teaching ◽  
Weinberg Equilibrium ◽  
Hardy Weinberg Equilibrium ◽  
Basic Concepts ◽  
The Cost

In an earlier paper (Smith & Baldwin, 2015), we explained the basic concepts of the Hardy-Weinberg equilibrium (HWeq) principle needed for meaningful understanding and for good teaching, emphasizing distinctions that are sometimes ignored at the cost of coherent understanding, and identifying nine shortcomings of most available Hardy-Weinberg activities and problem sets. In the present paper, we provide a 5E lesson plan based on that analysis and designed to avoid the shortcomings identified, including providing original data and focusing on understanding and topics that are interesting and meaningful to young people.

scholarly journals Allele Frequencies of 15 AmpFISTR Identifiler loci in the Nepalese population

2012 ◽  
Vol 10 (10) ◽  
pp. 20-23 ◽  
Author(s):  
Dinesh Kumar Jha ◽  
Luis Javier Martinez Gonzalez ◽  
Jiwan Prasad Rijal ◽  
Bhinu Shova Tuladhar ◽  
Nirajan Thapa Chhetri
Keyword(s):  
Allele Frequencies ◽  
Statistical Parameters ◽  
Weinberg Equilibrium ◽  
Allelic Frequencies ◽  
Str Loci ◽  
Scientific World ◽  
Hardy Weinberg Equilibrium

Allele frequencies for the 15 STR loci in the AmpFlSTR® Identifiler® and statistical parameters were estimated from a sample of 233 unrelated individuals from different area of Nepal. A total of 161 alleles were found, with corresponding allelic frequencies ranging from 0.0021 to 0.4077. The MP, PD, PIC, PE, TPI, Ho and He ranged from 0.0282 to 0.1511, 0.8489 to 0.9717, 0.6478 to 0.8700, 0.4546 to 0.7631, 1.7651 to 4.3148, 0.7167 to 0.8841 and 0.7009 to 0.8833 respectively. Deviations from the Hardy–Weinberg Equilibrium were observed for D16S539, D18S51, D21S11 and TPOX Markers. One new allele has been detected in the process. Scientific World, Vol. 10, No. 10, July 2012 p20-23 DOI: http://dx.doi.org/10.3126/sw.v10i10.6856

scholarly journals Novel intron 2 polymorphism in the melanophilin gene is in Hardy-Weinberg equilibrium and is not associated with coat color in goats

2013 ◽  
Vol 03 (03) ◽  
pp. 195-200 ◽  
Author(s):  
Mufliat A. Adefenwa ◽  
Brilliant O. Agaviezor ◽  
Sunday O. Peters ◽  
Matthew Wheto ◽  
Oludotun J. Ekundayo ◽  
...  
Keyword(s):  
Coat Color ◽  
Weinberg Equilibrium ◽  
Hardy Weinberg Equilibrium ◽  
Intron 2

scholarly journals Effects of genetic variation in the 20th intron of Sansui duck ATP2A2 gene on eggshell quality

2021 ◽  
Vol 3 (2) ◽  
Author(s):  
Junhan Mei ◽  
Yiyu Zhang ◽  
Minfang You ◽  
Chaomei Liao ◽  
Guanghui Tan ◽  
...  
Keyword(s):  
Direct Sequencing ◽  
Strong Linkage Disequilibrium ◽  
Strong Linkage ◽  
Weinberg Equilibrium ◽  
Atp2a2 Gene ◽  
Eggshell Quality ◽  
Hardy Weinberg Equilibrium ◽  
Intron Region ◽  
The Relationship

In order to explore the influence of the polymorphism in the 20 intron region of the Sansui duck ATP2A2 gene on the eggshell quality, this study used Primer Premier 5 software to design and synthesize a pair of primers in the 20 intron region, two-way direct sequencing and sequence alignment to mine SNPs Sites, SPSS 18.0 software was used to analyze the relationship between SNP sites and eggshell quality of Sansui duck. Results Three SNP sites were found in the 20 intron region of the ATP2A2 gene: g.40874 T>C, g.40920 G>A and g.40990 T=C, all of which were moderately polymorphic, at the site g.40874 T ＞C and g.40920 G＞A both deviated significantly from Hardy-Weinberg equilibrium (P>0.05), position g.40990 T=C accords with Hardy-Weinberg equilibrium (P<0.05), and position g.40874 T＞C There is a strong linkage disequilibrium between g.40990 T=C; a total of 4 haplotypes and 9 double types were detected at 3 SNP loci; the results of association analysis show that g.40874 T＞C mutation has an effect on eggshell strength The eggshell strength of CC genotype was significantly higher than that of TC and TT genotypes (P<0.05), and the eggshell weight of CC genotype was significantly higher than that of TC genotype (P<0.05), g. The 40990 T=C mutation has a significant effect on the eggshell strength, and the eggshell strength of the TC genotype is significantly higher than that of the TT genotype (P<0.05). In summary, the g.40874 T>C and g.40990 T=C found in the 20th intron region of the Sansui duck ATP2A2 gene may be the marker sites that affect the quality of the eggshell.

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