Anatomical variations in the circle of Willis in canines

2018 ◽  
Vol 47 (6) ◽  
pp. 609-612
Author(s):  
Toshiyuki Tanaka ◽  
Hideo Akiyoshi ◽  
Keiichiro Mie
VASA ◽  
2011 ◽  
Vol 40 (5) ◽  
pp. 404-407
Author(s):  
Maras ◽  
Tzormpatzoglou ◽  
Papas ◽  
Papanas ◽  
Kotsikoris ◽  
...  

Foetal-type posterior circle of Willis is a common anatomical variation with a variable degree of vessel asymmetry. In patients with this abnormality, carotid endarterectomy (CEA) may create cerebral hypo-perfusion intraoperatively, and this may be underestimated under general anaesthesia. There is currently no evidence that anatomical variations in the circle of Willis represent an independent risk factor for stroke. Moreover, there is a paucity of data on treating patients with such anatomical variations and co-existing ICA stenosis. We present a case of CEA under local anaesthesia (LA) in a 52-year-old female patient with symptomatic stenosis of the right ICA and coexistent foetal-type posterior circle of Willis. There were no post-operative complications and she was discharged free from symptoms. She was seen again 3 months later and was free from complications. This case higlights that LA should be strongly considered to enable better intra-operative neurological monitoring in the event of foetal-type posterior circle of Willis.


2018 ◽  
Vol 08 (04) ◽  
pp. 270-273
Author(s):  
Aisha Hassan Brohi ◽  
Kevin Joseph Jerome Borges ◽  
Gulraiz Hikmat Yar ◽  
Syed Nudrat Nawaid Shah ◽  
Nuzhat Hassan

In occlusive vascular brain diseases, the structure of the circle of Willis is of immense importance. A high percentage of variations have been reported in the arteries forming circle of Willis. These have profound clinical implications. With advances in interventional radiological procedures, the interventional radiologists and neurosurgeons need to have thorough knowledge of these variations. This article will help readers understand the significance of anatomical variations and their clinical effects.


2013 ◽  
Vol 24 (4) ◽  
pp. 325-330 ◽  
Author(s):  
Alex Förster ◽  
Ingo Nölte ◽  
Holger Wenz ◽  
Mansour Al-Zghloul ◽  
Hans U. Kerl ◽  
...  

2007 ◽  
Vol 40 (8) ◽  
pp. 1794-1805 ◽  
Author(s):  
J. Alastruey ◽  
K.H. Parker ◽  
J. Peiró ◽  
S.M. Byrd ◽  
S.J. Sherwin

2019 ◽  
Vol 78 (2) ◽  
pp. 259-266 ◽  
Author(s):  
J. Shatri ◽  
S. Cerkezi ◽  
V. Ademi ◽  
V. Reci ◽  
S. Bexheti

2021 ◽  
Author(s):  
James R. Ayre ◽  
Peter J. Bazira ◽  
Mohammed Abumattar ◽  
Haran N. Makwana ◽  
Katherine A. Sanders

2017 ◽  
Vol 4 (4) ◽  
pp. 1249 ◽  
Author(s):  
Ramanuj Singh ◽  
Ajay Babu Kannabathula ◽  
Himadri Sunam ◽  
Debajani Deka

Background: The circle of Willis (CW) is a vascular network formed at the base of skull in the interpeduncular fossa. Its anterior part is formed by the anterior cerebral artery, from either side. Anterior communicating artery connects the right and left anterior cerebral arteries. Posteriorly, the basilar artery divides into right and left posterior cerebral arteries and each join to ipsilateral internal carotid artery through a posterior communicating artery. Anterior communicating artery and posterior communicating arteries are important component of circle of Willis, acts as collateral channel to stabilize blood flow. In the present study, anatomical variations in the circle of Willis were noted.Methods: 75 apparently normal formalin fixed brain specimens were collected from human cadavers. 55 Normal anatomical pattern and 20 variations of circle of Willis were studied. The Circles of Willis arteries were then colored, photographed, numbered and the abnormalities, if any, were noted.Results: Twenty variations were noted. The most common variation observed is in the anterior communicating artery followed by some other variations like the Posterior communicating arteries, Anterior cerebral artery and posterior cerebral artery (PCA) was found in 20 specimens.Conclusions: Knowledge on of variations in the formation of Circle of Willis, all surgical interventions should be preceded by angiography. Awareness of these anatomical variations is important in the neurovascular procedures.


2021 ◽  
Vol 13 ◽  
Author(s):  
Futoshi Eto ◽  
Takeshi Yoshimoto ◽  
Shuhei Okazaki ◽  
Kunihiro Nishimura ◽  
Shiori Ogura ◽  
...  

IntroductionDysregulation of the RING finger protein 213 (RNF213) gene impairs vascular formation in experimental animal models. In addition, vascular abnormalities in the circle of Willis are associated with cerebrovascular disease. Here, we evaluated the relationship between the East Asian founder variant RNF213 p.R4810K and consequent anatomical variations in the circle of Willis in cerebrovascular disease.Patients and MethodsThe present study is an observational cross-sectional study. It included patients with acute anterior circulation non-cardioembolic stroke admitted to our institution within 7 days of symptom onset or last-known-well from 2011 to 2019, and those who participated in the National Cerebral and Cardiovascular Center Biobank. We compared anatomical variations of the vessels constituting the circle of Willis between RNF213 p.R4810K (c.14429G > A) variant carriers and non-carriers using magnetic resonance angiography and assessed the association between the variants and the presence of the vessels constituting the circle of Willis. Patients with moyamoya disease were excluded.ResultsFour hundred eighty-one patients [146 women (30%); median age 70 years; median baseline National Institutes of Health Stroke Scale score 5] were analyzed. The RNF213 p.R4810K variant carriers (n = 25) were more likely to have both posterior communicating arteries (PComAs) than the variant non-carriers (n = 456) (56% vs. 13%, P < 0.01). Furthermore, variant carriers were less likely to have an anterior communicating artery (AComA) than non-carriers (68% vs. 84%, P = 0.04). In a multivariate logistic regression analysis, the association of RNF213 p.R4810K variant carriers with the presence of both PComAs and the absence of AComA remained significant.ConclusionOur findings suggest that the RNF213 p.R4810K variant is an important factor in determining anatomical variations in the circle of Willis.


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