scholarly journals Association of inbreeding and regional equine leucocyte antigen homozygosity with the prevalence of insect bite hypersensitivity in Old Kladruber horse

2021 ◽  
Author(s):  
L. Vostry ◽  
H. Vostra‐Vydrova ◽  
J. Citek ◽  
G. Gorjanc ◽  
I. Curik
Keyword(s):  
Insect Bite Hypersensitivity

Genetic parameters of insect bite hypersensitivity in the Old Grey Kladruber horse

2017 ◽  
Vol 95 (1) ◽  
pp. 53
Author(s):  
J. Citek ◽  
L. Vostry ◽  
H. Vostra-Vydrova ◽  
M. Brzakova ◽  
V. Prantlova
Keyword(s):  
Genetic Parameters ◽  
Insect Bite Hypersensitivity

P6017 A high density genome-wide scan for genetic risk factors of insect bite hypersensitivity (IBH): A Horsegene Project Initiative

2016 ◽  
Vol 94 (suppl_4) ◽  
pp. 156-157
Author(s):  
B. D. Velie ◽  
M. Shrestha ◽  
L. Francois ◽  
A. Schurink ◽  
A. Stinckens ◽  
...  
Keyword(s):  
Risk Factors ◽  
Genetic Risk ◽  
Genetic Risk Factors ◽  
High Density ◽  
Genome Wide ◽  
Insect Bite Hypersensitivity ◽  
Genome Wide Scan

scholarly journals Allergen-Specific Cytokine Polarization Protects Shetland Ponies against Culicoides obsoletus-Induced Insect Bite Hypersensitivity

PLoS ONE ◽  
2015 ◽  
Vol 10 (4) ◽  
pp. e0122090 ◽  
Author(s):  
Chantal Meulenbroeks ◽  
Jaco J. van der Lugt ◽  
Nathalie M. A. van der Meide ◽  
Ton Willemse ◽  
Victor P. M. G. Rutten ◽  
...  
Keyword(s):  
Culicoides Obsoletus ◽  
Insect Bite Hypersensitivity

scholarly journals New Strategies for Prevention and Treatment of Insect Bite Hypersensitivity in Horses

2019 ◽  
Vol 8 (4) ◽  
pp. 303-312 ◽  
Author(s):  
Sigridur Jonsdottir ◽  
Iva Cvitas ◽  
Vilhjalmur Svansson ◽  
Antonia Fettelschloss-Gabriel ◽  
Sigurbjorg Torsteinsdottir ◽  
...  
Keyword(s):  
Neutralizing Antibodies ◽  
Clinical Signs ◽  
Therapeutic Vaccines ◽  
Allergen Specific Immunotherapy ◽  
Virus Like Particle ◽  
Prevention And Treatment ◽  
Prophylactic Vaccination ◽  
Insect Bite Hypersensitivity ◽  
Icelandic Horses ◽  
New Strategies

Abstract Purpose of Review Treatment of equine insect bite hypersensitivity (IBH) needs to be improved. Allergen-specific immunotherapy (ASIT), the only curative treatment of allergy, currently has only a limited efficacy for treatment of IBH. This review highlights the latest findings in prophylactic and therapeutic strategies. Recent Findings Prophylactic vaccination against IBH using recombinant Culicoides allergen has been developed in unexposed Icelandic horses and is ready to be tested. Therapeutic virus-like particle (VLP)–based vaccines targeting equine interleukin- (IL-) 5 or IL-31 improved clinical signs of IBH by induction of anti-cytokine antibodies thus reducing eosinophil counts or allergic pruritus, respectively. Summary First studies for development of ASIT using pure r-Culicoides allergens have yielded promising results and need now to be tested in clinical studies for both prevention and treatment of IBH. Therapeutic vaccines inducing neutralizing antibodies against IL-5 or IL-31 will be valuable future treatments for reduction of clinical signs of IBH.

scholarly journals Interleukin 31 in insect bite hypersensitivity—Alleviating clinical symptoms by active vaccination against itch

Allergy ◽  
2020 ◽  
Vol 75 (4) ◽  
pp. 862-871 ◽  
Author(s):  
Florian Olomski ◽  
Victoria Fettelschoss ◽  
Sigridur Jonsdottir ◽  
Katharina Birkmann ◽  
Franziska Thoms ◽  
...  
Keyword(s):  
Clinical Symptoms ◽  
Active Vaccination ◽  
Insect Bite Hypersensitivity

scholarly journals Erratum to “Genetic parameters of insect bite hypersensitivity in Dutch Friesian broodmares” (J. Anim. Sci. 89:1286–1293)

2011 ◽  
Vol 89 (6) ◽  
pp. 1952-1952
Author(s):  
A. Schurink ◽  
B. J. Ducro ◽  
H. C. M. Heuven ◽  
J. A. M. van Arendonk
Keyword(s):  
Genetic Parameters ◽  
Insect Bite Hypersensitivity
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