Nuclear mitochondrial pseudogenes in the cattle genome

2019 ◽  
Vol 51 (1) ◽  
pp. 148-149
Author(s):  
Stefan Hiendleder ◽  
Cynthia D.K. Bottema ◽  
Ronald M. Brunner
Keyword(s):  
BMC Biology ◽  
2019 ◽  
Vol 17 (1) ◽  
Author(s):  
Lingzhao Fang ◽  
Shuli Liu ◽  
Mei Liu ◽  
Xiaolong Kang ◽  
Shudai Lin ◽  
...  

2012 ◽  
Vol 12 (4) ◽  
pp. 609-624 ◽  
Author(s):  
George E. Liu ◽  
Derek M. Bickhart

BMC Genetics ◽  
2009 ◽  
Vol 10 (1) ◽  
Author(s):  
Rafael Villa-Angulo ◽  
Lakshmi K Matukumalli ◽  
Clare A Gill ◽  
Jungwoo Choi ◽  
Curtis P Van Tassell ◽  
...  

2011 ◽  
Vol 134 (1) ◽  
pp. 1-8 ◽  
Author(s):  
D.M. Larkin
Keyword(s):  

2017 ◽  
Vol 7 (1) ◽  
Author(s):  
Milad Khorramian Ghahfarokhi ◽  
Kianoush Dormiani ◽  
Ali Mohammadi ◽  
Farnoosh Jafarpour ◽  
Mohammad Hossein Nasr-Esfahani

2017 ◽  
Author(s):  
Yan Chen ◽  
Yining Liu ◽  
Min Du ◽  
Wengang Zhang ◽  
Xue Gao ◽  
...  

Integrating genomic information into cattle breeding is an important approach to exploring the molecular mechanism for complex traits related to diary and meat production. To assist with genomic-based selection, a reference map of interactome is needed to fully understand genotype-phenotype relationships. To this end we constructed a co-expression analysis of 92 tissues and this represents the first systematic exploration of gene-gene relationship in cattle. By using robust WGCNA (Weighted Gene Correlation Network Analysis), we described the gene co-expression network of 13,405 protein-coding genes from the cattle genome. Using the 5,000 genes with majority variations in expression across 92 tissues, we compiled a network with 72,306 co-associations and that provides functional insights into thousands of poorly characterized proteins. Further module identifications found 55 highly organized functional clusters representing diverse cellular activities. To demonstrate the re-use of our interaction for functional genomics analysis, we extracted a sub-network associated with DNA binding genes in cattle. The subnetwork was enriched within regulation of transcription from RNA polymerase II promoter representing central cellular functions. In addition, we identified 28 novel linker genes associated with more than 100 DNA binding genes. Our WGCNA-based co-expression network reconstruction will be a valuable resource for exploring the molecular mechanisms of incompletely characterized proteins and for elucidating larger-scale patterns of functional modulization in the cattle genome.


2016 ◽  
Vol 94 (suppl_5) ◽  
pp. 147-147
Author(s):  
G. E. Liu ◽  
L. Xu ◽  
R. Haasl ◽  
J. Sun ◽  
Y. Zhou ◽  
...  

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