Genetic variants in IL15 promoter affect transcription activity and intramuscular fat deposition in longissimus dorsi muscle of pigs

2017 ◽  
Vol 49 (1) ◽  
pp. 19-28
Author(s):  
D. He ◽  
Z. Jiang ◽  
Y. Tian ◽  
H. Han ◽  
M. Xia ◽  
...  
Keyword(s):  
Genetic Variants ◽  
Intramuscular Fat ◽  
Fat Deposition ◽  
Longissimus Dorsi ◽  
Transcription Activity ◽  
Longissimus Dorsi Muscle ◽  
Dorsi Muscle

The effect of variants in the promoter of BMPER on the intramuscular fat deposition in longissimus dorsi muscle of pigs

Gene ◽  
2014 ◽  
Vol 542 (2) ◽  
pp. 168-172 ◽  
Author(s):  
Zhi Liu ◽  
Wenxing Sun ◽  
Yongyan Zhao ◽  
Chunying Xu ◽  
Yingying Fu ◽  
...  
Keyword(s):  
Intramuscular Fat ◽  
Fat Deposition ◽  
Longissimus Dorsi ◽  
Longissimus Dorsi Muscle ◽  
Dorsi Muscle

Longissimus dorsi muscle label-free quantitative proteomic reveals biological mechanisms associated with intramuscular fat deposition

2018 ◽  
Vol 179 ◽  
pp. 30-41 ◽  
Author(s):  
Mirele D. Poleti ◽  
Luciana C.A. Regitano ◽  
Gustavo H.M.F. Souza ◽  
Aline S.M. Cesar ◽  
Rosineide C. Simas ◽  
...  
Keyword(s):  
Intramuscular Fat ◽  
Fat Deposition ◽  
Longissimus Dorsi ◽  
Label Free ◽  
Biological Mechanisms ◽  
Longissimus Dorsi Muscle ◽  
Dorsi Muscle

scholarly journals Data from proteomic analysis of bovine Longissimus dorsi muscle associated with intramuscular fat content

Data in Brief ◽  
2018 ◽  
Vol 19 ◽  
pp. 1314-1317 ◽  
Author(s):  
Mirele D. Poleti ◽  
Luciana C.A. Regitano ◽  
Gustavo H.M.F. Souza ◽  
Aline S.M. Cesar ◽  
Rosineide C. Simas ◽  
...  
Keyword(s):  
Proteomic Analysis ◽  
Intramuscular Fat ◽  
Fat Content ◽  
Longissimus Dorsi ◽  
Longissimus Dorsi Muscle ◽  
Dorsi Muscle ◽  
Intramuscular Fat Content

scholarly journals Genome-Wide Identification of RNA Editing Sites Affecting Intramuscular Fat in Pigs

Animals ◽  
2020 ◽  
Vol 10 (9) ◽  
pp. 1616
Author(s):  
Ligang Wang ◽  
Jingna Li ◽  
Xinhua Hou ◽  
Hua Yan ◽  
Longchao Zhang ◽  
...  
Keyword(s):  
Rna Editing ◽  
Human Insulin ◽  
Intramuscular Fat ◽  
Longissimus Dorsi ◽  
Sequencing Data ◽  
Protein Subunit ◽  
Growth Hormone Secretagogue Receptor ◽  
Growth Hormone Secretagogue ◽  
Longissimus Dorsi Muscle ◽  
Dorsi Muscle

Intramuscular fat (IMF) is essential for improving the palatability and flavor of meat, and it is strongly associated with human insulin resistance. RNA editing is a widespread regulating event in different tissues. Here, we investigated the global RNA editing difference of two groups of pig with different IMF contents to find the potential editing sites affecting IMF. In this research, RES-Scanner and REDItools were used to identify RNA editing sites based on the whole genome and transcriptome sequencing data of the high and low groups composed of three full-sib pairs with opposite IMF phenotypes. A total of 295 RNA editing sites were investigated in the longissimus dorsi muscle, and 90.17% of these sites caused A to G conversion. After annotation, most editing sites were located in noncoding regions (including five sites located on the 3′ UTR regions). Five editing sites (including two sites that could lead to nonsynonymous amino acid changes) were located in the exons of genes. A total of 36 intergroup (high and low IMF) differential RNA editing sites were found in 33 genes. Some candidate editing sites, such as sites in acyl-coenzymeA: cholesterol acyltransferase 1 (ACAT1), coatomer protein, subunit alpha (COPA), and nuclear receptor coactivator 3 (NCOA3), were selected as candidate RNA editing sites associated with IMF. One site located on the 3′ UTR region of growth hormone secretagogue receptor (GHSR) may regulate GHSR expression by affecting the interaction of miRNA and mRNA. In conclusion, we identified a total of 36 nonredundant RNA editing sites in the longissimus dorsi muscle, which may reveal the potential importance of RNA editing in IMF. Four were selected as candidate sites associated with IMF. Our findings provide some new insights of RNA editing function in pig longissimus dorsi muscle which useful for pig IMF breeding or human insulin resistances research.

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