Novel class II alpha MHC variability in a small peripheral Atlantic salmon population

2017 ◽  
Vol 48 (3) ◽  
pp. 370-372
Author(s):  
Kate L. Ciborowski ◽  
William C. Jordan ◽  
Carlos García de Leániz ◽  
Sofia Consuegra
Keyword(s):  
Atlantic Salmon ◽  
Class Ii ◽  
Salmon Population ◽  
Class Ii Alpha

scholarly journals Natural selection acts on Atlantic salmon major histocompatibility (MH) variability in the wild

2007 ◽  
Vol 274 (1611) ◽  
pp. 861-869 ◽  
Author(s):  
Elvira de Eyto ◽  
Philip McGinnity ◽  
Sofia Consuegra ◽  
Jamie Coughlan ◽  
Jarle Tufto ◽  
...  
Keyword(s):  
Natural Selection ◽  
Atlantic Salmon ◽  
Balancing Selection ◽  
Natural Populations ◽  
Class Ii ◽  
Major Histocompatibility ◽  
Genotype Frequencies ◽  
Fitness Consequences ◽  
In The Wild ◽  
Class Ii Alpha

Pathogen-driven balancing selection is thought to maintain polymorphism in major histocompatibility (MH) genes. However, there have been few empirical demonstrations of selection acting on MH loci in natural populations. To determine whether natural selection on MH genes has fitness consequences for wild Atlantic salmon in natural conditions, we compared observed genotype frequencies of Atlantic salmon ( Salmo salar ) surviving in a river six months after their introduction as eggs with frequencies expected from parental crosses. We found significant differences between expected and observed genotype frequencies at the MH class II alpha locus, but not at a MH class I-linked microsatellite or at seven non-MH-linked microsatellite loci. We therefore conclude that selection at the MH class II alpha locus was a result of disease-mediated natural selection, rather than any demographic event. We also show that survival was associated with additive allelic effects at the MH class II alpha locus. Our results have implications for both the conservation of wild salmon stocks and the management of disease in hatchery fish. We conclude that natural or hatchery populations have the best chance of dealing with episodic and variable disease challenges if MH genetic variation is preserved both within and among populations.

Size selection from fishways and potential evolutionary responses in a threatened Atlantic salmon population

2017 ◽  
Vol 33 (7) ◽  
pp. 1004-1015 ◽  
Author(s):  
G. A. Maynard ◽  
M. T. Kinnison ◽  
J. D. Zydlewski
Keyword(s):  
Atlantic Salmon ◽  
Size Selection ◽  
Salmon Population

scholarly journals Defective major histocompatibility complex class II assembly, transport, peptide acquisition, and CD4+ T cell selection in mice lacking invariant chain expression.

1993 ◽  
Vol 177 (6) ◽  
pp. 1699-1712 ◽  
Author(s):  
E K Bikoff ◽  
L Y Huang ◽  
V Episkopou ◽  
J van Meerwijk ◽  
R N Germain ◽  
...  
Keyword(s):  
Major Histocompatibility Complex ◽  
Mhc Class Ii ◽  
Critical Role ◽  
Class Ii ◽  
Intact Protein ◽  
Invariant Chain ◽  
Major Histocompatibility ◽  
Protein Antigens ◽  
Histocompatibility Complex ◽  
Class Ii Alpha

We used gene targeting techniques to produce mice lacking the invariant chain associated with major histocompatibility complex (MHC) class II molecules. Cells from these mice show a dramatic reduction in surface class II, resulting from both defective association of class II alpha and beta chains and markedly decreased post-Golgi transport. The few class II alpha/beta heterodimers reaching the cell surface behave as if empty or occupied by an easily displaced peptide, and display a distinct structure. Mutant spleen cells are defective in their ability to present intact protein antigens, but stimulate enhanced responses in the presence of peptides. These mutant mice have greatly reduced numbers of thymic and peripheral CD4+ T cells. Overall, this striking phenotype establishes that the invariant chain plays a critical role in regulating MHC class II expression and function in the intact animal.

Advances in Fish Tagging and Marking Technology

2012 ◽  
Keyword(s):  
Atlantic Salmon ◽  
Salmo Salar ◽  
Release Time ◽  
Tag Identification ◽  
Penobscot River ◽  
Salmon Population ◽  
Declining Populations ◽  
Simple Change ◽  
Using Data ◽  
Made In

<i>Abstract</i>.—Atlantic salmon <i>Salmo salar </i>smolts are stocked in the Penobscot River, Maine to supplement declining populations. Since 2000, approximately 550,000 hatchery smolts are annually released into the river, of which 32% of these (175,000) were marked with visual implant elastomer (VIE) tags indicating release time and location. Our study found that tag colors of adult returns were often misread due to confusion between green and yellow marks and between red and pink marks. Using data collected on mark readings in a controlled hatchery environment, we corrected for tag identification errors made in the field, thereby allowing adjustments to be made in the marked returns to accurately assess the number of returns from multiple stocking groups. When adult returns from multiple stocking groups were compared, significant differences were detected between stocking groups, including a three-fold difference between two of the stocking groups. Hence, a simple change in smolt stocking locations and times may be of value in the recovery of the Penobscot River salmon population.

scholarly journals Stable isotopes suggest the location of marine feeding grounds of South European Atlantic salmon in Greenland

2020 ◽  
Vol 77 (2) ◽  
pp. 593-603 ◽  
Author(s):  
Ana Almodóvar ◽  
Graciela G Nicola ◽  
Daniel Ayllón ◽  
Clive N Trueman ◽  
Ian Davidson ◽  
...  
Keyword(s):  
Atlantic Salmon ◽  
Population Decline ◽  
Migration Route ◽  
North Atlantic Current ◽  
Migration Routes ◽  
Δ13c And Δ15n ◽  
Δ13c Values ◽  
The North ◽  
Salmon Population ◽  
And Migration

Abstract Historical data on the oceanic distribution and migration routes of southernmost Atlantic salmon Salmo salar populations from Europe are almost non-existent, as no rigorous tagging initiatives have been conducted. Here, we used stable isotope data (δ13C and δ15N) of historic scale collections to identify the potential marine feeding areas of the largest salmon population in the Iberian Peninsula. Data were compared with published datasets from Northern Ireland, Wales, south England, and northeast UK coast, which correspond to series between 15- and 33-year long within the time period from 1958 to 2009. Temporal covariation in sea surface temperature, primary productivity, and δ13C values suggests that feeding areas of Iberian salmon are located around Greenland, both in the Labrador and the Irminger seas. Furthermore, δ13C values of Atlantic salmon from Canadian rivers reported in the literature are similar to those found in individuals from Spanish rivers. Our results suggest that Iberian salmon follow a westerly migration route towards Greenland instead of following the easterly branch of the North Atlantic current into the Norwegian Sea. Characterization of feeding patterns and migration routes might help to understand the causes of ongoing population decline and establish targeted conservation programmes for threatened Iberian salmon.

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