Effect of glycolic acid and EDTA on dentin mechanical properties

2021 ◽  
Author(s):  
Fernanda Andrade Marafiga ◽  
Ana Flávia Almeida Barbosa ◽  
Emmanuel João Nogueira Leal Silva ◽  
Matheus Albino Souza ◽  
Ana Paula Farina ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Glycolic Acid

scholarly journals Mechanical Properties and Bioactivity of Poly(Lactic Acid) Composites Containing Poly(Glycolic Acid) Fiber and Hydroxyapatite Particles

Nanomaterials ◽  
2021 ◽  
Vol 11 (1) ◽  
pp. 249
Author(s):  
Han-Seung Ko ◽  
Sangwoon Lee ◽  
Doyoung Lee ◽  
Jae Young Jho
Keyword(s):  
Mechanical Properties ◽  
Lactic Acid ◽  
Flexural Strength ◽  
Interfacial Adhesion ◽  
Glycolic Acid ◽  
Compact Bone ◽  
Poly Lactic Acid ◽  
Coupling Reactions ◽  
The Poor ◽  
Human Compact Bone

To enhance the mechanical strength and bioactivity of poly(lactic acid) (PLA) to the level that can be used as a material for spinal implants, poly(glycolic acid) (PGA) fibers and hydroxyapatite (HA) were introduced as fillers to PLA composites. To improve the poor interface between HA and PLA, HA was grafted by PLA to form HA-g-PLA through coupling reactions, and mixed with PLA. The size of the HA particles in the PLA matrix was observed to be reduced from several micrometers to sub-micrometer by grafting PLA onto HA. The tensile and flexural strength of PLA/HA-g-PLA composites were increased compared with those of PLA/HA, apparently due to the better dispersion of HA and stronger interfacial adhesion between the HA and PLA matrix. We also examined the effects of the length and frequency of grafted PLA chains on the tensile strength of the composites. By the addition of unidirectionally aligned PGA fibers, the flexural strength of the composites was greatly improved to a level comparable with human compact bone. In the bioactivity tests, the growth of apatite on the surface was fastest and most uniform in the PLA/PGA fiber/HA-g-PLA composite.

scholarly journals Effect of a new irrigant solution containing glycolic acid on smear layer removal and chemical/mechanical properties of dentin

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Débora Pereira Diniz Correia Barcellos ◽  
Ana Paula Farina ◽  
Ramiro Barcellos ◽  
Matheus Albino Souza ◽  
Márcia Borba ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Glycolic Acid ◽  
Smear Layer ◽  
Layer Removal

The effect of poly (lactic-co-glycolic) acid composition on the mechanical properties of electrospun fibrous mats

2017 ◽  
Vol 529 (1-2) ◽  
pp. 371-380 ◽  
Author(s):  
X. Liu ◽  
J. Aho ◽  
S. Baldursdottir ◽  
A. Bohr ◽  
H. Qu ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Acid Composition ◽  
Glycolic Acid

MECHANICAL PROPERTIES OF BIOABSORBABLE POLY (GLYCOLIC ACID) NERVE GUIDE TUBES AND DEGRADATION BEHAVFAOR

ASAIO Journal ◽  
2002 ◽  
Vol 48 (2) ◽  
pp. 198
Author(s):  
Satoshi Tanaka ◽  
Tatsuo Nakamura ◽  
Yasuhiko Shimizu ◽  
Toshikazu Takigawa ◽  
Shugo Nomura
Keyword(s):  
Mechanical Properties ◽  
Glycolic Acid

scholarly journals Insights into the structural dynamics of poly lactic-co-glycolic acid at terahertz frequencies

2019 ◽  
Vol 10 (3) ◽  
pp. 351-361 ◽  
Author(s):  
Talia A. Shmool ◽  
J. Axel Zeitler
Keyword(s):  
Mechanical Properties ◽  
Structural Dynamics ◽  
Glycolic Acid ◽  
Molecular Level ◽  
Dynamic Processes ◽  
Terahertz Frequencies

The mechanical properties of an amorphous copolymer are directly related to the dynamic processes occurring at the molecular level.

Electrostatic Spinning Preparation and Mechanical Properties of PLGA Fibers and Fiber Membrane

2013 ◽  
Vol 834-836 ◽  
pp. 847-854
Author(s):  
Le Lun Jiang ◽  
Yong Huang ◽  
Jin Tian Ling ◽  
Zhang Qi Feng ◽  
Xi Feng Qiao ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Tensile Strength ◽  
Glycolic Acid ◽  
Tensile Modulus ◽  
Fiber Membrane ◽  
Elongation At Break ◽  
Electrostatic Spinning ◽  
Fiber Membranes ◽  
Loading System ◽  
Main Factor

PLGA (polylactic-co-glycolic acid) is an ideal material for biodegradable medical suture. PLGA fibers and fiber membrane was prepared by using electrostatic spinning, the surface morphology of PLGA fibers and fiber membranes was observed by SEM, and mechanical properties of PLGA fibers and fiber membranes were tested by self-developed micro-force loading system. Experimental results were found that the arrangement of PLGA fibers due to surface tension and friction between fibers was the main factor on mechanical properties of PLGA fibers. The tensile strength of two fibers in winding arrangement was 1.81 times of fibers arranged in parallel at a given number. The tensile strength of three fibers in winding arrangement was 1.25 times of fibers arranged in parallel at a given number. For 80.6 % porosity and 1.028-5.764 mm width PLGA fiber membranes, tensile strength was 1.06-1.47 MPa, tensile modulus was 9.14-13.6 MPa, and elongation at break was 10.8 % to 11.6 %. The tension of fiber membranes increased with its width.

Evaluation of the in vitro biodegradation and biological behavior of poly(lactic-co-glycolic acid)/nano-fluorhydroxyapatite composite microsphere-sintered scaffold for bone tissue engineering

2017 ◽  
Vol 33 (2) ◽  
pp. 146-159 ◽  
Author(s):  
Mohammadreza Tahriri ◽  
Fathollah Moztarzadeh ◽  
Arash Tahriri ◽  
Hossein Eslami ◽  
Kimia Khoshroo ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Tissue Engineering ◽  
Weight Loss ◽  
Simulated Body Fluid ◽  
Bone Tissue Engineering ◽  
Bone Tissue ◽  
Body Fluid ◽  
Bone Repair ◽  
Glycolic Acid ◽  
Composite Scaffold

The objective of this research was to study the degradation and biological characteristics of the three-dimensional porous composite scaffold made of poly(lactic- co-glycolic acid)/nano-fluorhydroxyapatite microsphere using sintering method for potential bone tissue engineering. Our previous experimental results demonstrated that poly(lactic- co-glycolic acid)/nano-fluorhydroxyapatite composite scaffold with a ratio of 4:1 sintered at 90ºC for 2 h has the greatest mechanical properties and a proper pore structure for bone repair applications. The weight loss percentage of both poly(lactic- co-glycolic acid)/nano-fluorhydroxyapatite and poly(lactic- co-glycolic acid) scaffolds demonstrated a monotonic trend with increasing degradation time, that is, the incorporation of nano-fluorhydroxyapatite into polymeric scaffold could lead to weight loss in comparison with that of pure poly(lactic- co-glycolic acid). The pH change for composite scaffolds showed that there was a slight decrease until 2 weeks after immersion in simulated body fluid, followed by a significant increase in the pH of simulated body fluid without a scaffold at the end of immersion time. The mechanical properties of composite scaffold were higher than that of poly(lactic- co-glycolic acid) scaffold at total time of incubation in simulated body fluid; however, it should be noted that the incorporation of nano-fluorhydroxyapatite into composite scaffold leads to decline in the relatively significant mechanical strength and modulus during hydrolytic degradation. In addition, MTT assay and alkaline phosphatase activity results defined that a general trend of increasing cell viability was seen for poly(lactic- co-glycolic acid)/nano-fluorhydroxyapatite scaffold sintered by time when compared to control group. Eventually, experimental results exhibited poly(lactic- co-glycolic acid)/nano-fluorhydroxyapatite microsphere-sintered scaffold is a promising scaffold for bone repair.

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