scholarly journals Organ pathologies detected post‐mortem in patients receiving opioid agonist treatment for opioid use disorder: a nationwide 2‐year cross‐sectional study

Addiction ◽  
2021 ◽  
Author(s):  
Anne Berit Bech ◽  
Thomas Clausen ◽  
Helge Waal ◽  
Gerd Jorunn Møller Delaveris ◽  
Ivar Skeie
Keyword(s):  
Cross Sectional Study ◽  
Opioid Use Disorder ◽  
Post Mortem ◽  
Sectional Study ◽  
Opioid Use ◽  
Opioid Agonist ◽  
Cross Sectional ◽  
Opioid Agonist Treatment

Hypogonadism in opioid using males in an inner-city cohort: A cross-sectional study

2021 ◽  
Vol 17 (2) ◽  
pp. 135-144
Author(s):  
Leen Wehbeh, MD ◽  
Adrian S. Dobs, MD, MHS ◽  
Todd T. Brown, MD, PhD
Keyword(s):  
Drug Users ◽  
Free Testosterone ◽  
Cross Sectional Study ◽  
Opioid Use Disorder ◽  
Male Hypogonadism ◽  
Abdominal Adiposity ◽  
Sectional Study ◽  
Opioid Use ◽  
Cross Sectional ◽  
Heroin Use

Objectives: The link between male hypogonadism and opioids is well-established, but whether there is a difference in the frequency of hypogonadism between heroin and methadone for treatment of opioid use disorder (OUD) has not been determined.Design: Cross-sectional.Setting, patients, and participants: Male drug users and nonusers matched for socioeconomic status between 18 and 65 years, recruited in Baltimore as part of the study of HIV, injection drug use, nutrition, and endocrinology (SHINE). Methods: Hypogonadism was defined as low free testosterone 50 pg/mL. Participants were categorized into three groups based on opioid use: (1) NONE, (2) methadone use as treatment of OUD (METHADONE), and (3) Heroin use (HEROIN). This third group was further divided to mild (MH), and heavy (HH) heroin use. We used multiple logistic regression to examine the association between hypogonadism and different groups.Results: The cohort consisted of 189 men, 94 percent black, average age 43 years, with high HIV (56 percent) and HCV (38 percent) prevalence. 24 percent had hypogonadism. Compared to NONE, there were higher odds of hypogonadism in METHADONE (aOR 3.46; 95 percent CI [1.34,8.93]; p = 0.01) but not in HEROIN. After dividing HEROIN into MH and HH, there were higher odds of hypogonadism in HH compared to NONE (aOR 3.27; 95 percent CI [1.12,9.53]; p = 0.03) but not in MH.Conclusions: Methadone used for treatment of OUD was associated with male hypogonadism similar to heavy heroin use. Targeted hypogonadism screening and treatment may be warranted in this population to reduce its health consequences such as sexual dysfunction, osteoporosis, and abdominal adiposity.

scholarly journals Prevalence of Opioid Dependence and Opioid Agonist Treatment in the Berlin Custodial Setting: A Cross-Sectional Study

2020 ◽  
Vol 11 ◽  
Author(s):  
Kira von Bernuth ◽  
Peter Seidel ◽  
Julia Krebs ◽  
Marc Lehmann ◽  
Britta Neumann ◽  
...  
Keyword(s):  
Opioid Dependence ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Opioid Agonist ◽  
Cross Sectional ◽  
Opioid Agonist Treatment

Buprenorphine use and disparities in access among emergency department patients with opioid use disorder: A cross-sectional study

2021 ◽  
Vol 130 ◽  
pp. 108405
Author(s):  
Matthew Robbins ◽  
Rachel Haroz ◽  
Anthony Mazzarelli ◽  
David Clements ◽  
Christopher W. Jones ◽  
...  
Keyword(s):  
Emergency Department ◽  
Cross Sectional Study ◽  
Opioid Use Disorder ◽  
Sectional Study ◽  
Opioid Use ◽  
Cross Sectional ◽  
Emergency Department Patients

scholarly journals Suicidal motivations reported by opioid overdose survivors: A cross-sectional study of adults with opioid use disorder

2019 ◽  
Vol 205 ◽  
pp. 107612 ◽  
Author(s):  
Hilary S. Connery ◽  
Nadine Taghian ◽  
Jungjin Kim ◽  
Margaret Griffin ◽  
Ian R.H. Rockett ◽  
...  
Keyword(s):  
Cross Sectional Study ◽  
Opioid Use Disorder ◽  
Opioid Overdose ◽  
Sectional Study ◽  
Opioid Use ◽  
Cross Sectional

scholarly journals Trends in prescription opioid use and dose trajectories before opioid use disorder or overdose in US adults from 2006 to 2016: A cross-sectional study

PLoS Medicine ◽  
2019 ◽  
Vol 16 (11) ◽  
pp. e1002941 ◽  
Author(s):  
Yu-Jung Jenny Wei ◽  
Cheng Chen ◽  
Roger Fillingim ◽  
Siegfried O. Schmidt ◽  
Almut G. Winterstein
Keyword(s):  
Cross Sectional Study ◽  
Opioid Use Disorder ◽  
Prescription Opioid ◽  
Sectional Study ◽  
Opioid Use ◽  
Cross Sectional ◽  
Prescription Opioid Use

Understanding current practice of opioid use disorder management in emergency departments across Canada: A cross-sectional study

CJEM ◽  
2020 ◽  
Vol 22 (4) ◽  
pp. 494-498
Author(s):  
Patricia Hoyeck ◽  
David Wiercigroch ◽  
Cara Clarke ◽  
Rahim Moineddin ◽  
Hasan Sheikh ◽  
...  
Keyword(s):  
Emergency Departments ◽  
Management Practices ◽  
Cross Sectional Study ◽  
Opioid Use Disorder ◽  
Emergency Physicians ◽  
Sectional Study ◽  
Opioid Use ◽  
Current Management ◽  
Cross Sectional ◽  
Canadian Association

ABSTRACTObjectiveOpioid-related deaths are increasing at alarming rates in Canada, with a 34% increase from 2016 to 2017. Patients with opioid use disorder often visit emergency departments (ED), presenting an opportunity to engage patients in treatment. Buprenorphine-naloxone is first-line treatment for opioid use disorder, but current management in the ED is unknown. This study aimed to characterize opioid use disorder management in the ED.MethodsWe conducted a cross-sectional study of emergency physicians across Canada. A survey was circulated electronically to the Canadian Association of Emergency Physicians members. Participants were asked about their current management practices, satisfaction, and helpfulness of resources. SAS (version 9.4) was used for statistical analysis. We dichotomized Likert-scale responses to approximate relative risk ratios via a log binomial analysis.ResultsThe survey was completed by 179 participants for a response rate of 11.1%; 143 (79.9%) physicians treated patients with opioid use disorder more than once a week. Only 7% (n = 13) of respondents always/often gave buprenorphine in the ED. Referral to an addiction clinic where patients were seen quickly was deemed the most helpful (90.5%, n = 162). Physicians who reported satisfaction with opioid use disorder management were four times more likely to prescribe buprenorphine in the ED or as an outpatient script (RR = 4.41, CI = 2.33–8.33, p < 0.01; RR = 4.51, CI = 2.21–9.22, p < 0.01).ConclusionThis study found that buprenorphine is not frequently prescribed in the ED setting, which is incongruent with the 2018 guidelines. Care coordination and on-site support were helpful to ED physicians. Hospitals should use knowledge translation strategies to improve the care of patients with an opioid use disorder.

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