Electroacupuncture alleviates spatial memory deficits in METH withdrawal mice by enhancing astrocyte‐mediated glutamate clearance in the dCA1

2021 ◽  
Author(s):  
Teng He ◽  
Nanqin Li ◽  
Pengbo Shi ◽  
Xing Xu ◽  
Jiaxun Nie ◽  
...  
Keyword(s):  
Spatial Memory ◽  
Memory Deficits

Detecting spatial memory deficits beyond blindness in tg2576 Alzheimer mice

2013 ◽  
Vol 34 (3) ◽  
pp. 716-730 ◽  
Author(s):  
Nour Yassine ◽  
Anelise Lazaris ◽  
Cornelia Dorner-Ciossek ◽  
Olivier Després ◽  
Laurence Meyer ◽  
...  
Keyword(s):  
Spatial Memory ◽  
Memory Deficits

MeHg Suppressed Neuronal Potency of Hippocampal NSCs Contributing to the Puberal Spatial Memory Deficits

2016 ◽  
Vol 172 (2) ◽  
pp. 424-436 ◽  
Author(s):  
Jianying Tian ◽  
Yougen Luo ◽  
Weiwei Chen ◽  
Shengsen Yang ◽  
Hao Wang ◽  
...  
Keyword(s):  
Spatial Memory ◽  
Memory Deficits

scholarly journals Inhibition of Src family kinases improves cognitive function after intraventricular hemorrhage or intraventricular thrombin

2016 ◽  
Vol 37 (7) ◽  
pp. 2359-2367 ◽  
Author(s):  
Da Zhi Liu ◽  
Ben Waldau ◽  
Bradley P Ander ◽  
Xinhua Zhan ◽  
Boryana Stamova ◽  
...  
Keyword(s):  
Spatial Memory ◽  
Hippocampal Neurons ◽  
Intraventricular Hemorrhage ◽  
Memory Loss ◽  
Neuronal Cell ◽  
Memory Deficits ◽  
Src Family Kinases ◽  
Intraventricular Injection ◽  
Src Family Kinase ◽  
Autologous Whole Blood

Intraventricular hemorrhage causes spatial memory loss, but the mechanism remains unknown. Our recent studies demonstrated that traumatic brain injury activates Src family kinases, which cause spatial memory loss. To test whether the spatial memory loss was due to blood in the ventricles, which activated Src family kinases, we infused autologous whole blood or thrombin into the lateral ventricles of adult rats to model non-traumatic intraventricular hemorrhage. Hippocampal neuron loss was examined 1 day to 5 weeks later. Spatial memory function was assessed 29 to 33 days later using the Morris water maze. Five weeks after the ventricular injections of blood or thrombin, there was death of most hippocampal neurons and significant memory deficits compared with sham operated controls. These data show that intraventricular thrombin is sufficient to kill hippocampal neurons and produce spatial memory loss. In addition, systemic administration of the non-specific Src family kinase inhibitor PP2 or intraventricular injection of siRNA-Fyn, a Src family kinase family member, prevented hippocampal neuronal loss and spatial memory deficits following intraventricular hemorrhage. The data support the conclusions that thrombin mediates the hippocampal neuronal cell death and spatial memory deficits produced by intraventricular blood and that these can be blocked by non-specific inhibition of Src family kinases or by inhibiting Fyn.

scholarly journals Dietary omega-3 deficiency exacerbates inflammation and reveals spatial memory deficits in mice exposed to lipopolysaccharide during gestation

2018 ◽  
Vol 73 ◽  
pp. 427-440 ◽  
Author(s):  
V.F. Labrousse ◽  
Q. Leyrolle ◽  
C. Amadieu ◽  
A. Aubert ◽  
A Sere ◽  
...  
Keyword(s):  
Spatial Memory ◽  
Memory Deficits ◽  
Omega 3

scholarly journals Male-Specific cAMP Signaling in the Hippocampus Controls Spatial Memory Deficits in a Mouse Model of Autism and Intellectual Disability

2019 ◽  
Vol 85 (9) ◽  
pp. 760-768 ◽  
Author(s):  
Marta Zamarbide ◽  
Adele Mossa ◽  
Pablo Muñoz-Llancao ◽  
Molly K. Wilkinson ◽  
Heather L. Pond ◽  
...  
Keyword(s):  
Intellectual Disability ◽  
Mouse Model ◽  
Spatial Memory ◽  
Memory Deficits ◽  
Camp Signaling ◽  
Male Specific

Crocin-protected malathion-induced spatial memory deficits by inhibiting TAU protein hyperphosphorylation and antiapoptotic effects

2019 ◽  
Vol 23 (3) ◽  
pp. 221-236 ◽  
Author(s):  
Leila Mohammadzadeh ◽  
Khalil Abnous ◽  
Bibi Marjan Razavi ◽  
Hossein Hosseinzadeh
Keyword(s):  
Spatial Memory ◽  
Tau Protein ◽  
Memory Deficits

Spatial memory deficits in maternal iron deficiency paradigms are associated with altered glucocorticoid levels

2013 ◽  
Vol 64 (1) ◽  
pp. 26-36 ◽  
Author(s):  
Sayali C. Ranade ◽  
Sarfaraz Nawaz ◽  
Arnab Chakrabarti ◽  
Pierre Gressens ◽  
Shyamala Mani
Keyword(s):  
Iron Deficiency ◽  
Spatial Memory ◽  
Memory Deficits ◽  
Maternal Iron

The role of nitric oxide in the PKA inhibitor induced spatial memory deficits in rat: Involvement of choline acetyltransferase

2013 ◽  
Vol 714 (1-3) ◽  
pp. 478-485 ◽  
Author(s):  
Sheyda Najafi ◽  
Borna Payandemehr ◽  
Kaveh Tabrizian ◽  
Marjan Shariatpanahi ◽  
Ehsan Nassireslami ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Spatial Memory ◽  
Choline Acetyltransferase ◽  
Memory Deficits
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