scholarly journals An acetylcholine‐dopamine interaction in the nucleus accumbens and its involvement in ethanol's dopamine‐releasing effect

2020 ◽  
Author(s):  
Anna Loftén ◽  
Louise Adermark ◽  
Mia Ericson ◽  
Bo Söderpalm
Keyword(s):  
Nucleus Accumbens ◽  
Releasing Effect

scholarly journals Menthol facilitates dopamine-releasing effect of nicotine in rat nucleus accumbens

2018 ◽  
Vol 175 ◽  
pp. 47-52 ◽  
Author(s):  
Meiyu Zhang ◽  
Erin Harrison ◽  
Lisa Biswas ◽  
Thuy Tran ◽  
Xiu Liu
Keyword(s):  
Nucleus Accumbens ◽  
Rat Nucleus Accumbens ◽  
Releasing Effect

Musical Anhedonia

2020 ◽  
Vol 31 (2) ◽  
pp. 62-68
Author(s):  
Sara E. Holm ◽  
Alexander Schmidt ◽  
Christoph J. Ploner
Keyword(s):  
Quality Of Life ◽  
Nucleus Accumbens ◽  
Brain Damage ◽  
Parietal Cortex ◽  
Neurological Disorders ◽  
Brain Regions ◽  
Precise Information ◽  
Exact Localization ◽  
High Prevalence

Abstract. Some people, although they are perfectly healthy and happy, cannot enjoy music. These individuals have musical anhedonia, a condition which can be congenital or may occur after focal brain damage. To date, only a few cases of acquired musical anhedonia have been reported in the literature with lesions of the temporo-parietal cortex being particularly important. Even less literature exists on congenital musical anhedonia, in which impaired connectivity of temporal brain regions with the Nucleus accumbens is implicated. Nonetheless, there is no precise information on the prevalence, causes or exact localization of both congenital and acquired musical anhedonia. However, the frequent involvement of temporo-parietal brain regions in neurological disorders such as stroke suggest the possibility of a high prevalence of this disorder, which leads to a considerable reduction in the quality of life.

Chemogenetic inhibition of dopaminergic projections to the nucleus accumbens has sexually dimorphic effects in the rat gambling task.

2020 ◽  
Vol 134 (4) ◽  
pp. 309-322 ◽  
Author(s):  
Tristan J. Hynes ◽  
Jacqueline-Marie M. Ferland ◽  
Tanya L. Feng ◽  
Wendy K. Adams ◽  
Mason M. Silveira ◽  
...  
Keyword(s):  
Nucleus Accumbens ◽  
Sexually Dimorphic ◽  
Gambling Task

Tiefenhirnstiumulation des Nucleus Accumbens bei therapieresistenter Alkoholabhängigkeit – erste Erfahrungen

Suchttherapie ◽  
2009 ◽  
Vol 10 (S 01) ◽  
Author(s):  
UJ Müller ◽  
J Voges ◽  
J Heinze ◽  
M Heldmann ◽  
I Galazky ◽  
...  
Keyword(s):  
Nucleus Accumbens

Haemostatic Platelet Plug Formation in the Isolated Rabbit Mesenteric Preparation - An Analysis of Red Blood Cell Participation

1980 ◽  
Vol 44 (01) ◽  
pp. 006-008 ◽  
Author(s):  
D Bergqvist ◽  
K-E Arfors
Keyword(s):  
Whole Blood ◽  
Platelet Rich Plasma ◽  
Adenosine Diphosphate ◽  
In Vitro Test ◽  
Pharmacological Agents ◽  
Vitro Test ◽  
Releasing Effect ◽  
Plug Formation

SummaryIn a model using an isolated rabbit mesenteric preparation microvessels were transected and the time until haemostatic plugs formed was registered. Perfusion of platelet rich plasma gave no haemostasis whereas whole blood did. Addition of chlorpromazine or adenosine to the whole blood significantly prolonged the time for haemostasis, and addition of ADP to the platelet rich plasma significantly shortened it. It is concluded that red cells are necessary for a normal haemostasis in this model, probably by a combination of a haemodynamic and ADP releasing effect.The fundamental role of platelets in haemostatic plug formation is unquestionable but there are still problems concerning the stimulus for this process to start. Three platelet aggregating substances have been discussed – thrombin, adenosine diphosphate (ADP) and collagen. Evidence speaking in favour of thrombin is, however, very minimal, and the discussion has to be focused on collagen and ADP. In an in vitro system using polyethylene tubings we have shown that "haemostasis" can be obtained without the presence of collagen but against these results can be argued that it is only another in vitro test for platelet aggregation (1).To be able to induce haemostasis in this model, however, the presence of red blood cells is necessary. To further study this problem we have developed a model where haemostatic plug formation can be studied in the isolated rabbit mesentery and we have briefly reported on this (2).Thus, it is possible to perfuse the vessels with whole blood as well as with platelet rich plasma (PRP) and different pharmacological agents of importance.

Oxytocin attenuates nucleus accumbens-connectivity during alcohol cue presentation: Evidence from a recent randomized cross-over study

2020 ◽  
Author(s):  
P Bach ◽  
I Reinhard ◽  
S Bühler ◽  
S Vollstädt-Klein ◽  
F Kiefer ◽  
...  
Keyword(s):  
Nucleus Accumbens
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