A randomized, double‐blind, placebo‐controlled study of the kappa opioid receptor antagonist, CERC‐501, in a human laboratory model of smoking behavior

Jermaine D. Jones; Shanna Babalonis; Ronald Marcus; Bradley Vince; Debra Kelsh; Michelle R. Lofwall; Heather Fraser; Blake Paterson; Suky Martinez; Diana M. Martinez; Edward V. Nunes; Sharon L. Walsh; Sandra D. Comer

doi:10.1111/adb.12799

A randomized, double‐blind, placebo‐controlled study of the kappa opioid receptor antagonist, CERC‐501, in a human laboratory model of smoking behavior

Addiction Biology ◽

10.1111/adb.12799 ◽

2019 ◽

Vol 25 (4) ◽

Cited By ~ 2

Author(s):

Jermaine D. Jones ◽

Shanna Babalonis ◽

Ronald Marcus ◽

Bradley Vince ◽

Debra Kelsh ◽

...

Keyword(s):

Receptor Antagonist ◽

Opioid Receptor ◽

Smoking Behavior ◽

Kappa Opioid Receptor ◽

Controlled Study ◽

Laboratory Model ◽

Kappa Opioid ◽

Double Blind ◽

Double Blind Placebo ◽

Human Laboratory

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A Double-Blind, Placebo-Controlled Study of the Tolerability and Efficacy of a New Kappa-Opioid Receptor Agonist (R-84760) in Patients with Pain after Dental Surgery

Clinical Drug Investigation ◽

10.2165/00044011-200020060-00003 ◽

2000 ◽

Vol 20 (6) ◽

pp. 409-414

Author(s):

R.A. Seymour ◽

L. Stassen ◽

U. Moore ◽

J.E. Hawkesford ◽

T. Oshima ◽

...

Keyword(s):

Opioid Receptor ◽

Receptor Agonist ◽

Kappa Opioid Receptor ◽

Controlled Study ◽

Kappa Opioid ◽

Double Blind ◽

Dental Surgery ◽

Double Blind Placebo ◽

Opioid Receptor Agonist

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Effect of Difelikefalin, a Selective Kappa Opioid Receptor Agonist, on Respiratory Depression: A Randomized, Double‐Blind, Placebo‐Controlled Trial

Clinical and Translational Science ◽

10.1111/cts.13042 ◽

2021 ◽

Author(s):

Eugene R. Viscusi ◽

Marc C. Torjman ◽

Catherine L. Munera ◽

Joseph W. Stauffer ◽

Beatrice S. Setnik ◽

...

Keyword(s):

Respiratory Depression ◽

Opioid Receptor ◽

Receptor Agonist ◽

Controlled Trial ◽

Kappa Opioid Receptor ◽

Kappa Opioid ◽

Double Blind ◽

Double Blind Placebo ◽

Opioid Receptor Agonist

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PM308. A phase 3, multicenter randomized double blind placebo controlled study of the opioid receptor antagonist –Odelepran the treatment of alcohol addiction.

The International Journal of Neuropsychopharmacology ◽

10.1093/ijnp/pyw041.308 ◽

2016 ◽

Vol 19 (Suppl_1) ◽

pp. 10-10 ◽

Cited By ~ 1

Keyword(s):

Receptor Antagonist ◽

Opioid Receptor ◽

Alcohol Addiction ◽

Controlled Study ◽

Phase 3 ◽

Double Blind ◽

Double Blind Placebo ◽

Opioid Receptor Antagonist

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Faculty Opinions recommendation of Chronic peripheral administration of kappa-opioid receptor antagonist advances puberty onset associated with acceleration of pulsatile luteinizing hormone secretion in female rats.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.718110987.793483835 ◽

2013 ◽

Author(s):

Pamela Mellon ◽

Alexander Kauffman

Keyword(s):

Luteinizing Hormone ◽

Receptor Antagonist ◽

Opioid Receptor ◽

Hormone Secretion ◽

Kappa Opioid Receptor ◽

Female Rats ◽

Luteinizing Hormone Secretion ◽

Kappa Opioid ◽

Opioid Receptor Antagonist ◽

Puberty Onset

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Itching-like behavior: A common effect of the kappa opioid receptor antagonist 5'-guanidinonaltrindole and the biased kappa opioid receptor agonist 6'-guanidinonaltrindole in mice

Medicine in Drug Discovery ◽

10.1016/j.medidd.2021.100097 ◽

2021 ◽

pp. 100097

Author(s):

Alan Cowan ◽

Lee-Yuan Liu-Chen ◽

Saadet Inan

Keyword(s):

Receptor Antagonist ◽

Opioid Receptor ◽

Receptor Agonist ◽

Kappa Opioid Receptor ◽

Kappa Opioid ◽

Opioid Receptor Antagonist ◽

Common Effect ◽

Opioid Receptor Agonist

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Faculty Opinions recommendation of Relugolix, an oral gonadotropin-releasing hormone receptor antagonist, reduces endometriosis-associated pain in a dose-response manner: a randomized, double-blind, placebo-controlled study.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.738625631.793590472 ◽

2021 ◽

Author(s):

Kaei Nasu

Keyword(s):

Receptor Antagonist ◽

Dose Response ◽

Hormone Receptor ◽

Gonadotropin Releasing Hormone ◽

Controlled Study ◽

Double Blind ◽

Double Blind Placebo ◽

Releasing Hormone ◽

Gonadotropin Releasing Hormone Receptor

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Relugolix, an oral gonadotropin-releasing hormone receptor antagonist, reduces endometriosis-associated pain in a dose–response manner: a randomized, double-blind, placebo-controlled study

Fertility and Sterility ◽

10.1016/j.fertnstert.2020.07.055 ◽

2020 ◽

Author(s):

Yutaka Osuga ◽

Yoshifumi Seki ◽

Masataka Tanimoto ◽

Takeru Kusumoto ◽

Kentarou Kudou ◽

...

Keyword(s):

Receptor Antagonist ◽

Dose Response ◽

Hormone Receptor ◽

Gonadotropin Releasing Hormone ◽

Controlled Study ◽

Double Blind ◽

Double Blind Placebo ◽

Releasing Hormone ◽

Gonadotropin Releasing Hormone Receptor

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Attenuation of cannabinoid-induced inhibition of medullary dorsal horn neurons by a kappa-opioid receptor antagonist

Brain Research ◽

10.1016/j.brainres.2010.08.073 ◽

2010 ◽

Vol 1359 ◽

pp. 81-89 ◽

Cited By ~ 3

Author(s):

Akiko Okada-Ogawa ◽

Masayuki Kurose ◽

Ian D. Meng

Keyword(s):

Receptor Antagonist ◽

Dorsal Horn ◽

Opioid Receptor ◽

Kappa Opioid Receptor ◽

Kappa Opioid ◽

Dorsal Horn Neurons ◽

Opioid Receptor Antagonist ◽

Medullary Dorsal Horn

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Modeling analysis of the new kappa opioid receptor antagonist tracer [11C]LY2795050 in humans

NeuroImage ◽

10.1016/j.neuroimage.2010.04.221 ◽

2010 ◽

Vol 52 ◽

pp. S39

Author(s):

Giampaolo Tomasi ◽

Shu-Fei Lin ◽

Ming Zheng ◽

Beata Planeta-Wilson ◽

S. Henry ◽

...

Keyword(s):

Receptor Antagonist ◽

Opioid Receptor ◽

Kappa Opioid Receptor ◽

Kappa Opioid ◽

Opioid Receptor Antagonist ◽

Modeling Analysis

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Reinstatement of cocaine place-conditioning prevented by the peptide kappa-opioid receptor antagonist arodyn

European Journal of Pharmacology ◽

10.1016/j.ejphar.2007.05.007 ◽

2007 ◽

Vol 569 (1-2) ◽

pp. 84-89 ◽

Cited By ~ 90

Author(s):

A.N. Carey ◽

K. Borozny ◽

J.V. Aldrich ◽

J.P. McLaughlin

Keyword(s):

Receptor Antagonist ◽

Opioid Receptor ◽

Kappa Opioid Receptor ◽

Place Conditioning ◽

Kappa Opioid ◽

Opioid Receptor Antagonist

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