Deep brain stimulation of the orbitofrontal cortex prevents the development and reinstatement of morphine place preference

2019 ◽  
Vol 25 (4) ◽  
Author(s):  
Golnaz Fakhrieh‐Asl ◽  
Seyed Shahabeddin Sadr ◽  
Seyed Morteza Karimian ◽  
Esmail Riahi
Keyword(s):  
Deep Brain Stimulation ◽  
Brain Stimulation ◽  
Orbitofrontal Cortex ◽  
Place Preference ◽  
Deep Brain ◽  
Stimulation Of

scholarly journals Deep Brain Stimulation of the ventral striatum impairs extinction of morphine place preference (LB76)

2014 ◽  
Vol 28 (S1) ◽  
Author(s):  
Janelle Miranda ◽  
Freddyson Martinez ◽  
José Rodríguez ◽  
Fabricio Do Monte ◽  
Oscar Muñiz ◽  
...  
Keyword(s):  
Deep Brain Stimulation ◽  
Brain Stimulation ◽  
Ventral Striatum ◽  
Place Preference ◽  
Deep Brain ◽  
Stimulation Of

Deep brain stimulation modulates hypothalamic-brainstem fibers in cluster headache: case report

2020 ◽  
Vol 132 (3) ◽  
pp. 717-720 ◽  
Author(s):  
Sérgio A. F. Dantas ◽  
Eduardo J. L. Alho ◽  
Juliano J. da Silva ◽  
Nilson N. Mendes Neto ◽  
Erich Talamoni Fonoff ◽  
...  
Keyword(s):  
Deep Brain Stimulation ◽  
Cluster Headache ◽  
Brain Stimulation ◽  
Clinical Effects ◽  
Chronic Stimulation ◽  
Mammillary Bodies ◽  
Fiber Tracts ◽  
White Matter Region ◽  
Deep Brain ◽  
Stimulation Of

Hypothalamic deep brain stimulation (DBS) has been used for more than a decade to treat cluster headache (CH) but its mechanisms remain poorly understood. The authors have successfully treated a patient with CH using hypothalamic DBS and found that the contact used for chronic stimulation was located in a white matter region posterior to the mammillary bodies. Fiber tracts crossing that region were the medial forebrain bundle and those interconnecting the hypothalamus and brainstem, including the dorsal longitudinal fasciculus. Because the stimulation of axons is an important mechanism of DBS, some of its clinical effects in CH may be related to the stimulation of fibers interconnecting the hypothalamus and brainstem.

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