scholarly journals Clozapine treatment and risk of severe COVID‐19 infection

2021 ◽  
Author(s):  
Anna Ohlis ◽  
Alma Sörberg Wallin ◽  
Anna Sarafis ◽  
Hugo Sjöqvist ◽  
James H MacCabe ◽  
...  
Keyword(s):  
Clozapine Treatment

Safety of a Clozapine Trial Following Quetiapine-Induced Leukopenia: A Case Report

2019 ◽  
Vol 14 (1) ◽  
pp. 80-83 ◽  
Author(s):  
Asma H. Almaghrebi
Keyword(s):  
Treatment Options ◽  
Young Female ◽  
Similar Reaction ◽  
Careful Monitoring ◽  
Treatment Resistant ◽  
Blood Cell Count ◽  
Antipsychotic Medications ◽  
Case Presentation ◽  
Clozapine Treatment ◽  
History Of

Background: The clozapine-derivative quetiapine has been shown in some cases to cause leukopenia and neutropenia. Case Presentation: We reported on a case of a young female diagnosed with treatment-resistant schizophrenia. After failed trials of three antipsychotic medications and despite a history of quetiapineinduced leukopenia, clozapine treatment was introduced due to the severity of the patient’s symptoms, the limited effective treatment options, and a lack of guidelines on this issue. Result: Over a ten-week period of clozapine treatment at 700 mg per day, the patient developed agranulocytosis. Her white blood cell count sharply dropped to 1.6 &#215; 10<sup>9</sup> L, and her neutrophils decreased to 0.1 &#215; 10<sup>9</sup> L. There had been no similar reaction to her previous medications (carbamazepine, risperidone, and haloperidol). Conclusion: The safety of clozapine in a patient who has previously experienced leukopenia and neutropenia with quetiapine requires further investigation. Increased attention should be paid to such cases. Careful monitoring and slow titration are advisable.

scholarly journals Transient drop in the neutrophil count during COVID-19 regardless of clozapine treatment in patients with mental illness

2021 ◽  
Author(s):  
Gabriel Vallecillo ◽  
Josep Marti-Bonany ◽  
Maria José Robles ◽  
Joan Ramón Fortuny ◽  
Fernando Lana ◽  
...  
Keyword(s):  
Mental Illness ◽  
Neutrophil Count ◽  
Clozapine Treatment

Increases in triglyceride levels are associated with clinical response to clozapine treatment

2013 ◽  
Vol 27 (4) ◽  
pp. 401-403 ◽  
Author(s):  
John Lally ◽  
Anne Gallagher ◽  
Emma Bainbridge ◽  
Gloria Avalos ◽  
Mohamed Ahmed ◽  
...  
Keyword(s):  
Clinical Response ◽  
Clozapine Treatment

History of substance abuse and response to clozapine treatment

1993 ◽  
Vol 9 (2-3) ◽  
pp. 258
Author(s):  
Peter Buckley ◽  
HerbertY. Meltzer
Keyword(s):  
Substance Abuse ◽  
Clozapine Treatment ◽  
History Of
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