scholarly journals Independent and Interactive Effects of OPRM1 and DAT1 Polymorphisms on Alcohol Consumption and Subjective Responses in Social Drinkers

2017 ◽  
Vol 41 (6) ◽  
pp. 1093-1104 ◽  
Author(s):  
Elise M. Weerts ◽  
Gary S. Wand ◽  
Brion Maher ◽  
Xiaoqiang Xu ◽  
Mary Ann Stephens ◽  
...  
Keyword(s):  
Alcohol Consumption ◽  
Interactive Effects ◽  
Subjective Responses ◽  
Social Drinkers

Should fertile women quit drinking alcohol to produce better quality oocytes?

Zygote ◽  
2020 ◽  
pp. 1-3
Author(s):  
Burcu Ozbakir ◽  
Pinar Tulay
Keyword(s):  
Alcohol Consumption ◽  
Young Women ◽  
Antral Follicle ◽  
Antral Follicle Count ◽  
Control Group ◽  
Social Drinkers ◽  
Antral Follicles ◽  
Healthy Women ◽  
Significant Difference

Summary Alcohol consumption has long been shown to affect both fetal health and pregnancy. In this study, antral follicle count, maturation level of oocytes including morphological assessment and number of metaphase I (MI), metaphase II (MII) and germinal vesicle (GV) stage oocytes obtained from young women (age < 30 years old) with or without alcohol consumption were investigated. In total, 20 healthy women who were social drinkers and 36 healthy women who do not consume alcohol were involved in this study. Women in both study and control groups were undergoing controlled ovarian stimulation. The antral follicle count and the number and quality of the oocytes retrieved were evaluated and recorded. In total, 635 antral follicles, 1098 follicles and 1014 oocytes with 820 MII, 72 MI and 78 GV stage oocytes were collected from the social drinkers. In the control group, 628 antral follicles, 1136 follicles and 1085 oocytes with 838 MII, 93 MI and 102 GV stage oocytes were evaluated. The results of this study showed that the antral follicle count was very similar in both groups. The number of oocytes and MII stage oocytes was slightly higher in the control group, although it was not a significant difference. This study showed that although the consumption of alcohol may have adverse effects post-implantation, it may not have a solid effect during oogenesis in young women. The results of this study are especially important in clinical settings as some women who are social drinkers undergo in vitro fertilization treatments.

scholarly journals Interactive Effects of OPRM1 and DAT1 Genetic Variation on Subjective Responses to Alcohol

2014 ◽  
Vol 49 (3) ◽  
pp. 261-270 ◽  
Author(s):  
Lara A. Ray ◽  
Spencer Bujarski ◽  
Lindsay M. Squeglia ◽  
James R. Ashenhurst ◽  
Raymond F. Anton
Keyword(s):  
Genetic Variation ◽  
Interactive Effects ◽  
Subjective Responses

scholarly journals Association between the DRD2 gene Taq1A (C32806T) polymorphism and alcohol consumption in social drinkers

2005 ◽  
Vol 5 (2) ◽  
pp. 96-101 ◽  
Author(s):  
M R Munafò ◽  
E C Johnstone ◽  
K I Welsh ◽  
R T Walton
Keyword(s):  
Alcohol Consumption ◽  
Drd2 Gene ◽  
Social Drinkers

Differences in Smoking Topography and Subjective Responses to Smoking Among African American and White Menthol and Non-Menthol Smokers

2020 ◽  
Vol 22 (10) ◽  
pp. 1718-1725 ◽  
Author(s):  
Tommy Gunawan ◽  
Laura M Juliano
Keyword(s):  
African American ◽  
Health Disparities ◽  
Nicotine Dependence ◽  
Smoking Behavior ◽  
Sensory Stimulation ◽  
Smoke Exposure ◽  
Interactive Effects ◽  
Future Research ◽  
Subjective Responses ◽  
Smoking Topography

Abstract Introduction It has been suggested that menthol increases exposure to harmful elements of smoking and makes smoking more rewarding, easier to initiate, and harder to quit. Isolating the direct effects of menthol is challenging as African American (AA) race and menthol preference are highly overlapping. This study evaluated smoking behavior and subjective responses among a balanced sample of AA and white menthol and non-menthol smokers. In addition, smoking topography (ST) was compared to naturalistic smoking (NS) and interactions with menthol and race were explored. Aims and Methods Smokers (N = 100) smoked and rated their preferred brand of cigarettes via ST or NS during two laboratory visits (counterbalanced). Results Controlling for baseline differences among the groups (eg, nicotine dependence), menthol smokers took shorter and smaller puffs and AA smokers took longer puffs, but there were no differences in total puff volume, carbon monoxide, or other ST parameters. Menthol smokers reported greater urge reduction and lower sensory stimulation. The smoking method (ST vs. NS) had no effects on smoking behavior or exposure. Cigarettes smoked via ST were rated stronger. Differences in satisfaction based on the smoking method interacted with race and menthol status. Ratings of aversion differed by race and menthol status. Conclusions Menthol was not associated with increased smoke exposure or reward (except for urge reduction). ST caused minimal experimental reactivity relative to NS. Additional research that isolates the effects of menthol and examines potential interactive effects with race and other variables is needed to better understand its role in smoking-related health disparities. Implications Menthol and non-menthol smokers differed on some demographic variables and menthol preference was associated with greater nicotine dependence and greater urge reduction after smoking. Menthol was not associated with greater smoke exposure. Future research that investigates the unique risks associated with menthol and examines potential interactive effects with race and other related variables is warranted to better understand the role of menthol in smoking-related health disparities.

scholarly journals High‐risk social drinkers and heavy drinkers display similar rates of alcohol consumption

2019 ◽  
Vol 25 (2) ◽  
Author(s):  
Matthew E. Sloan ◽  
Joshua L. Gowin ◽  
Roshni Janakiraman ◽  
Corbin D. Ester ◽  
Joel Stoddard ◽  
...  
Keyword(s):  
High Risk ◽  
Alcohol Consumption ◽  
Social Drinkers ◽  
Heavy Drinkers

Association Between the Functional Polymorphism of Catechol-O-Methyltransferase Gene and Alcohol Consumption Among Social Drinkers

2000 ◽  
Vol 24 (2) ◽  
pp. 135-139 ◽  
Author(s):  
Jussi Kauhanen ◽  
Tero Hallikainen ◽  
Tomi-Pekka Tuomainen ◽  
Markku Koulu ◽  
Matti K. Karvonen ◽  
...  
Keyword(s):  
Alcohol Consumption ◽  
Functional Polymorphism ◽  
Social Drinkers ◽  
Methyltransferase Gene
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