scholarly journals The Impact of Prenatal Alcohol Exposure on Hippocampal-Dependent Outcome Measures is Influenced by Prenatal and Early-Life Rearing Conditions

2015 ◽  
Vol 39 (4) ◽  
pp. 631-639 ◽  
Author(s):  
Kevin K. Caldwell ◽  
Samantha L. Goggin ◽  
Matthew T. Labrecque ◽  
Andrea M. Allan
Keyword(s):  
Outcome Measures ◽  
Early Life ◽  
Prenatal Alcohol Exposure ◽  
Alcohol Exposure ◽  
Rearing Conditions ◽  
Prenatal Alcohol ◽  
The Impact

Attention: Prenatal alcohol and continuities of vigilance and attentional problems from 4 through 14 years

1995 ◽  
Vol 7 (3) ◽  
pp. 419-446 ◽  
Author(s):  
Ann P. Streissguth ◽  
Fred L. Bookstein ◽  
Paul D. Sampson ◽  
Helen M. Barr
Keyword(s):  
Latent Variable ◽  
Prenatal Alcohol Exposure ◽  
Alcohol Exposure ◽  
Teacher Ratings ◽  
Self Report ◽  
False Alarms ◽  
Vigilance Performance ◽  
Grade Teacher ◽  
Prenatal Alcohol ◽  
The Impact

AbstractThis study examined the longitudinal components of vigilance performance and attentional behaviors across the ages of 4, 7, and 14 years of life as they relate to prenatal alcohol exposure assessed by maternal self-report in midpregnancy for a cohort of 512 children. The vigilance score most salient for prenatal alcohol across this 10-year developmental period was Standard Deviation of Reaction Time (SDRT). Also salient were False Alarms (FA) on the AX task, impulsive errors reflecting difficulty in withholding a response. All 19 of the children with poorest scores on a Vigilance Latent Variable (LV) at 14 years had scored low on a similarly-defined Vigilance LV at age 7 years. Cross-lagged correlations revealed that the 7-year Vigilance LV not only predicted second-grade teacher ratings of attention a year later (r = – .38), but also predicted fourth-fifth-grade teacher ratings of attention (r = – .36). These data reveal considerable consistency across time in the impact of prenatal alcohol on child/adolescent vigilance performance and attention between 4 and 14 years of age.

Synthesizing Animal and Human Studies of Prenatal Alcohol Exposure

2001 ◽  
Vol 7 (5) ◽  
pp. 648-649 ◽  
Author(s):  
Paul D. Connor
Keyword(s):  
Fetal Alcohol Syndrome ◽  
Prenatal Alcohol Exposure ◽  
Alcohol Exposure ◽  
Fetal Alcohol ◽  
Behavioral Disturbances ◽  
Quarter Century ◽  
Prenatal Alcohol ◽  
Primary Focus ◽  
Maternal Alcohol Abuse ◽  
The Impact

The primary focus of this volume is on the impact of alcohol on brain development. It is a perfect example of how research on both animals and humans can interact to produce very important findings. In the case of prenatal alcohol exposure, dialogue between animal and human researchers has proved to be very profitable for both lines of research. Initial observations by human researchers identified a syndrome of facial stigmata, physical malformations, and early behavioral disturbances that was related to maternal alcohol abuse during pregnancy. They gave this syndrome the name Fetal Alcohol Syndrome. However, human researchers were unable to state unequivocally that prenatal alcohol exposure was teratogenic to the fetus. Thus, they turned to animal researchers who were able to model Fetal Alcohol Syndrome in a variety of animals and to confirm the teratogenicity of alcohol on the developing fetus. The quarter century of studies of the damage caused by prenatal alcohol exposure is replete with such interactions between these two groups of researchers. Without the input and pioneering studies of animal researchers on the effects of prenatal alcohol exposure, human researchers would have much less understanding of the damage caused by alcohol exposure in utero or insights into possible treatment or remediation strategies for those damaged by alcohol exposure.

scholarly journals Cardiac Orienting Responses Differentiate the Impact of Prenatal Alcohol Exposure in Ukrainian Toddlers

2016 ◽  
Vol 40 (11) ◽  
pp. 2377-2384 ◽  
Author(s):  
Julie A. Kable ◽  
Claire D. Coles ◽  
Kenneth L. Jones ◽  
Lyubov Yevtushok ◽  
Yaroslav Kulikovsky ◽  
...  
Keyword(s):  
Prenatal Alcohol Exposure ◽  
Alcohol Exposure ◽  
Prenatal Alcohol ◽  
The Impact

scholarly journals Effects of early-life adversity on immune function are mediated by prenatal environment: Role of prenatal alcohol exposure

2017 ◽  
Vol 66 ◽  
pp. 210-220 ◽  
Author(s):  
Charlis Raineki ◽  
Tamara S. Bodnar ◽  
Parker J. Holman ◽  
Samantha L. Baglot ◽  
Ni Lan ◽  
...  
Keyword(s):  
Immune Function ◽  
Early Life ◽  
Prenatal Alcohol Exposure ◽  
Alcohol Exposure ◽  
Early Life Adversity ◽  
Prenatal Environment ◽  
Prenatal Alcohol

scholarly journals Gestational age and socioeconomic status as mediators for the impact of prenatal alcohol exposure on development at 6 months

2018 ◽  
Vol 111 (12) ◽  
pp. 789-796 ◽  
Author(s):  
Claire D. Coles ◽  
Julie A. Kable ◽  
Irina V Granovska ◽  
Ala O. Pashtepa ◽  
Larisa D. Plotka ◽  
...  
Keyword(s):  
Socioeconomic Status ◽  
Gestational Age ◽  
Prenatal Alcohol Exposure ◽  
Alcohol Exposure ◽  
Prenatal Alcohol ◽  
The Impact

scholarly journals Effects of prenatal alcohol exposure on language, speech and communication outcomes: a review longitudinal studies

2018 ◽  
Vol 31 (2) ◽  
pp. 74-83 ◽  
Author(s):  
Gaironeesa Hendricks ◽  
Susan Malcolm-Smith ◽  
Colleen Adnams ◽  
Dan Joseph Stein ◽  
Kirsten Ann Mary Donald
Keyword(s):  
Longitudinal Studies ◽  
Citation Index ◽  
Prenatal Alcohol Exposure ◽  
Alcohol Exposure ◽  
Alcohol Group ◽  
Contextual Risk ◽  
Expressive Communication ◽  
Preschool Period ◽  
Prenatal Alcohol ◽  
The Impact

AbstractObjectiveThe aim of this paper was to provide a systematic review and update on the available longitudinal studies on the impact of prenatal alcohol exposure (PAE) on language, speech and communication development, as well as associated potential environmental confounders during the preschool period.MethodsA literature search was restricted to English, full‐text, peer‐reviewed, longitudinal studies in from 1970 until present: PUBMed, Scopus, Web of Science {C-e Collection, Biological Abstracts, KCI-Kean Journal Database, Russian Science Citation Index, SciELO Citation Index, Zoological Rec-d}, Academic Search Premier (Africa-Wide Information, CINAHL, MEDLINE, PsycINFO. Keywords included: prenatal alcohol exposure (PAE); speech or language or communication outcomes; neurocognitive or neurodevelopment or neurobehavioral or neurobehavioural; infant or baby or toddler or preschooler; longitudinal or follow-up. The inclusion criteria included (i) longitudinal cohorts with at least 2 time-points; (ii) association of light, moderate or heavy PAE on language, speech or communication delay, development or disorder; (iii) environmental confounders; (iv) infants up to preschool age.ResultsSix studies satisfied the threshold for inclusion. Three studies reported that PAE was significantly associated with receptive or expressive delay. These studies demonstrated lower scores on either receptive or expressive communication in the alcohol group in comparison to the non-alcohol group, even after controlling for environmental factors up to 36 months.ConclusionEvidence from the longitudinal studies reviewed suggest that PAE influenced delays in receptive and expressive communication up to 36 months. Contextual risk factors played a significant role in language development over time and especially as children approached school age.

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